Počet záznamů: 1

DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks

  1. 1.
    0328689 - UEB-Q 2010 RIV GB eng J - Článek v odborném periodiku
    Waterworth, W.M. - Kozák, Jaroslav - Provost, C.M. - Bray, C.M. - Angelis, Karel - West, C.E.
    DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks.
    BMC Plant Biology. Roč. 9, art.no.79 (2009), s. 1-12 ISSN 1471-2229
    Grant CEP: GA MŠk 1M0505; GA MŠk(CZ) LC06004
    Výzkumný záměr: CEZ:AV0Z50380511
    Klíčová slova: ARABIDOPSIS-THALIANA * T-DNA * COMET ASSAY
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 3.774, rok: 2009

    DNA ligase enzymes catalyse the joining of adjacent polynucleotides and as such play important roles in DNA replication and repair pathways. Eukaryotes possess multiple DNA ligases with distinct roles in DNA metabolism, with clear differences in the functions of DNA ligase orthologues between animals, yeast and plants. DNA ligase 1, present in all eukaryotes, plays critical roles in both DNA repair and replication and is indispensable for cell viability.
    Trvalý link: http://hdl.handle.net/11104/0174941