Počet záznamů: 1

Arginine vasopressin and its analogues--the influence of position 2 modification with 3,3-diphenylalanine enantiomers. Highly potent V2 agonists

  1. 1.
    0327397 - UOCHB-X 2010 RIV FR eng J - Článek v odborném periodiku
    Kwiatkowska, A. - Sobolewski, D. - Prahl, A. - Borovičková, Lenka - Slaninová, Jiřina - Lammek, B.
    Arginine vasopressin and its analogues--the influence of position 2 modification with 3,3-diphenylalanine enantiomers. Highly potent V2 agonists.
    European Journal of Medicinal Chemistry. Roč. 44, č. 7 (2009), s. 2862-2867 ISSN 0223-5234
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: arginine vasopressin analogues * AVP * 3,3-diphenylalanine enantiomers * V2 agonists * antidiuretic activity
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 3.269, rok: 2009

    Introduction of 3,3-diphenyl-L-alanine or its D-enantiomer into position 2 of arginine vasopressin results in preservation or increase and prolongation of antidiuretic activity, transformation of uterotonic property in antagonistic one and cancelation the effect on blood pressure.
    Trvalý link: http://hdl.handle.net/11104/0174225