Search results
- 1.0443559 - FGÚ 2016 RIV US eng J - Journal Article
Gryčová, Lenka - Holendová, Blanka - Lánský, Zdeněk - Bumba, Ladislav - Jirků, Michaela - Boušová, Kristýna - Teisinger, Jan
Ca2+ Binding Protein S100A1 Competes with Calmodulin and PIP2 for Binding Site on the C-Terminus of the TPRV1 Receptor.
ACS Chemical Neuroscience. Roč. 6, č. 3 (2015), s. 386-392. ISSN 1948-7193. E-ISSN 1948-7193
R&D Projects: GA ČR(CZ) GAP301/10/1159; GA ČR(CZ) GAP207/11/0717; GA ČR(CZ) GA15-11851S; GA ČR(CZ) GBP304/12/G069; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036 ; RVO:67985823 ; RVO:61388971
Keywords : TRPV1 * vanilloid receptor * calmodulin * S100A1 * calcium binding protein * surface plasmon resonance * fluorescence anisotropy
Subject RIV: CE - Biochemistry
Impact factor: 4.348, year: 2015
Permanent Link: http://hdl.handle.net/11104/0246246 - 2.0428039 - FGÚ 2015 RIV CZ eng J - Journal Article
Boukalová, Štěpána - Touška, Filip - Maršáková, Lenka - Hynková, Anna - Surá, Lucie - Chvojka, Štěpán - Dittert, Ivan - Vlachová, Viktorie
Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful?
Physiological Research. Roč. 63, Suppl.1 (2014), S205-S213. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA305/09/0081; GA ČR(CZ) GBP304/12/G069
Grant - others:Univerzita Karlova(CZ) 500512; Univerzita Karlova(CZ) 888513
Institutional support: RVO:67985823
Keywords : transient receptor potential * ion channel * mutagenesis * vanilloid receptor * gating
Subject RIV: ED - Physiology
Impact factor: 1.293, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233479 - 3.0394052 - FGÚ 2014 RIV NL eng J - Journal Article
Boukalová, Štěpána - Teisinger, Jan - Vlachová, Viktorie
Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel.
Biochimica Et Biophysica Acta-Molecular Cell Research. Roč. 1833, č. 3 (2013), s. 520-528. ISSN 0167-4889. E-ISSN 1879-2596
R&D Projects: GA ČR(CZ) GA305/09/0081; GA ČR(CZ) GAP301/10/1159; GA ČR(CZ) GBP304/12/G069
Institutional support: RVO:67985823
Keywords : vanilloid receptor subtype 1 * transient receptor potential * gating * tryptophan-scanning * mutagenesis
Subject RIV: ED - Physiology
Impact factor: 5.297, year: 2013
Permanent Link: http://hdl.handle.net/11104/0222377 - 4.0382324 - FGÚ 2013 RIV CZ cze M - Monography Chapter
Vlachová, Viktorie - Vyklický st., Ladislav
Buněčné a molekulární mechanizmy nocicepce.
[Cellular and molecular mechanism of nociception.]
Bolest. Monografie algeziologie. 2. přeprac., dopl. Praha: Tigis, 2012 - (Rokyta, R.; Kršiak, M.; Kozák, J.), s. 48-65. ISBN 978-80-87323-02-1
R&D Projects: GA ČR(CZ) GA305/09/0081
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : nociception * patch clamp * vanilloid receptor
Subject RIV: ED - Physiology
Permanent Link: http://hdl.handle.net/11104/0212576 - 5.0376809 - FGÚ 2013 RIV CZ cze J - Journal Article
Maršáková, Lenka - Vlachová, Viktorie
Kafr:účinná látka s neznámým mechanizmem působení.
[Camphor:an effective compound with an unknown mechanism of action.]
Bolest. Roč. 15, č. 1 (2012), s. 16-22. ISSN 1212-0634
R&D Projects: GA ČR(CZ) GA305/09/0081
Grant - others:Univerzita Karlova(CZ) 25409
Institutional research plan: CEZ:AV0Z50110509
Keywords : vanilloid receptor * camphor * transient receptor potential
Subject RIV: ED - Physiology
Permanent Link: http://hdl.handle.net/11104/0209119 - 6.0376808 - FGÚ 2013 RIV US eng J - Journal Article
Maršáková, Lenka - Touška, Filip - Krůšek, Jan - Vlachová, Viktorie
Pore Helix Domain Is Critical to Camphor Sensitivity of Transient Receptor Potential Vanilloid 1 Channel.
Anesthesiology. Roč. 116, č. 4 (2012), s. 903-917. ISSN 0003-3022. E-ISSN 1528-1175
R&D Projects: GA ČR(CZ) GA305/09/0081; GA ČR(CZ) GA202/09/0806; GA ČR(CZ) GD305/08/H037; GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554; GA ČR(CZ) GBP304/12/G069
Grant - others:Univerzita Karlova(CZ) 25409
Institutional research plan: CEZ:AV0Z50110509
Keywords : vanilloid receptor * camphor * transient receptor potential
Subject RIV: ED - Physiology
Impact factor: 5.163, year: 2012
Permanent Link: http://hdl.handle.net/11104/0209118 - 7.0358917 - FGÚ 2012 RIV NL eng J - Journal Article
Touška, Filip - Maršáková, Lenka - Teisinger, Jan - Vlachová, Viktorie
A “Cute” Desensitization of TRPV1.
Current Pharmaceutical Biotechnology. Roč. 12, č. 1 (2011), s. 122-129. ISSN 1389-2010. E-ISSN 1873-4316
R&D Projects: GA ČR GA305/09/0081; GA ČR(CZ) GAP301/10/1159; GA AV ČR(CZ) IAA600110701; GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554
Grant - others:Univerzita Karlova(CZ) 43-259 052
Institutional research plan: CEZ:AV0Z50110509
Keywords : capsaicin * analgesia * vanilloid receptor
Subject RIV: FH - Neurology
Impact factor: 2.805, year: 2011
Permanent Link: http://hdl.handle.net/11104/0196825 - 8.0354172 - FGÚ 2011 RIV US eng J - Journal Article
Boukalová, Štěpána - Maršáková, Lenka - Teisinger, Jan - Vlachová, Viktorie
Conserved Residues within the Putative S4–S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels.
Journal of Biological Chemistry. Roč. 285, č. 53 (2010), s. 41455-41462. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GA305/09/0081; GA ČR GAP301/10/1159; GA AV ČR(CZ) IAA600110701; GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554
Grant - others:Univerzita Karlova(CZ) 26110
Institutional research plan: CEZ:AV0Z50110509
Keywords : vanilloid receptor * voltage sensor * transient receptor potential
Subject RIV: FH - Neurology
Impact factor: 5.328, year: 2010
Permanent Link: http://hdl.handle.net/11104/0193233 - 9.0329481 - FGÚ 2010 RIV NL eng J - Journal Article
Benedikt, Jan - Samad, Abdul - Ettrich, Rüdiger - Teisinger, Jan - Vlachová, Viktorie
Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.
[Esenciální úloha domnělé oblasti S6 vnitřního póru v procesech aktivace lidského TRPA1 kanálu.]
Biochimica Et Biophysica Acta-Molecular Cell Research. Roč. 1793, č. 7 (2009), s. 1279-1288. ISSN 0167-4889. E-ISSN 1879-2596
R&D Projects: GA ČR(CZ) GA305/06/0319; GA ČR GA305/09/0081; GA ČR(CZ) GA303/07/0915; GA AV ČR(CZ) IAA600110701; GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554
Grant - others:EC(XE) LSHM-CT-2007-037765; GA MŠk(CZ) LC06010
Program: LC
Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z60870520
Keywords : TRPA1 * channel * vanilloid receptor
Subject RIV: ED - Physiology
Impact factor: 4.374, year: 2009
Permanent Link: http://hdl.handle.net/11104/0175505 - 10.0324444 - FGÚ 2009 RIV CZ cze L - Prototype, f. module
Vlachová, Viktorie - Teisinger, Jan
Rekombinantní protein potkaního vaniloidního receptoru podtypu 1 (TRPV1) s funkčně ověřenou dvojitou mutací TRPV1-S502A/T704I odstraňující kapsaicinovou citlivost při zachování citlivosti na kyseliny a teplotní podněty.
[Recombinant rat vanilloid receptor subtype 1 (TRPV1) with functionally approved double mutation TRPV1-S502A/T704I, which eliminates capsaicin sensitivity but retains its sensitivity to low pH and temperature.]
Internal code: TRPV1-S502A/T704I ; 2007
Technical parameters: Rekombinantní bílkovina odvozená od potkaního vanilodního receptoru podtypu 1 TRPV1-S502A/T704I
Economic parameters: Odhad: 250 tis. Kč
R&D Projects: GA ČR(CZ) GA305/06/0319; GA ČR(CZ) GA303/07/0915; GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50110509
Keywords : recombinant protein * vanilloid receptor subtype 1 * TRP receptors
Subject RIV: ED - Physiology
Permanent Link: http://hdl.handle.net/11104/0172143