Search results

  1. 1.
    0585467 - MBÚ 2025 RIV NL eng J - Journal Article
    Lepesheva, Anna - Grobarčíková, Michaela - Osičková, Adriana - Jurnečka, David - Knoblochová, Šárka - Čížková, Monika - Osička, Radim - Šebo, Peter - Mašín, Jiří
    Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
    Biochimica Et Biophysica Acta-Biomembranes. Roč. 1866, č. 5 (2024), s. 184311. ISSN 0005-2736. E-ISSN 1879-2642
    R&D Projects: GA ČR(CZ) GA22-15825S; GA ČR(CZ) GA22-01558S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
    Research Infrastructure: EATRIS-CZ IV - 90253; CIISB III - 90242
    Institutional support: RVO:61388971
    Keywords : RTX toxin * Adenylate cyclase toxin * α-Hemolysin * Chimera * Fatty acylation * Cytotoxicity
    OECD category: Microbiology
    Impact factor: 3.4, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0005273624000427?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0353157
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    Modification of the RTX.pdf03 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0576018 - MBÚ 2024 RIV DK eng J - Journal Article
    Kuzma, J. - Zavala-Meneses, Sofía Guadalupe - Škultéty, L'udovít - Chmelař, D. - Ficik, J. - Palcova, L.
    Antibiotic resistance and biofilm-forming ability of a-toxin-positive Clostridium septicum isolates worsen patient prognosis.
    Acta Pathologica Microbiologica et Immunologica Scandinavica. Roč. 131, č. 8 (2023), s. 434-441. ISSN 0903-4641. E-ISSN 1600-0463
    Institutional support: RVO:61388971
    Keywords : Alpha toxin * antibiotic resistance * biofilm * Clostridium septicum * flagellin
    OECD category: Microbiology
    Impact factor: 2.8, year: 2022
    Method of publishing: Limited access
    https://onlinelibrary.wiley.com/doi/10.1111/apm.13338
    Permanent Link: https://hdl.handle.net/11104/0345769
     
     
  3. 3.
    0575651 - MBÚ 2024 RIV NL eng J - Journal Article
    Chen, G. - Wang, H. - Bumba, Ladislav - Mašín, Jiří - Šebo, Peter - Li, H.
    The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity.
    Journal of Biological Chemistry. Roč. 299, č. 9 (2023), č. článku 105150. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) LM2023053; GA MŠMT(CZ) EF18_046/0015974
    Research Infrastructure: CIISB III - 90242
    Institutional support: RVO:61388971
    Keywords : adenylate cyclase * bacterial toxin * optical tweezers * protein folding * single-molecule biophysics
    OECD category: Microbiology
    Impact factor: 4.8, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0021925823021786?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0345406
    FileDownloadSizeCommentaryVersionAccess
    The adenylate cyclase toxin RTX domain follows JBC_2023 II .pdf13.5 MBPublisher’s postprintopen-access
     
     
  4. 4.
    0573968 - MBÚ 2024 RIV NL eng J - Journal Article
    Osičková, Adriana - Knoblochová, Šárka - Bumba, Ladislav - Man, Petr - Kalaninová, Zuzana - Lepesheva, Anna - Jurnečka, David - Čížková, Monika - Biedermannová, Lada - Goldsmith, J. A. - Maynard, J. A. - McLellan, J. S. - Osička, Radim - Šebo, Peter - Mašín, Jiří
    A conserved tryptophan in the acylated segment of RTX toxins controls their βinf2/inf integrin–independent cell penetration.
    Journal of Biological Chemistry. Roč. 299, č. 8 (2023), č. článku 104978. ISSN 0021-9258. E-ISSN 1083-351X
    R&D Projects: GA ČR(CZ) GA22-01558S; GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EF18_046/0015974; GA ČR(CZ) GX19-27630X
    Research Infrastructure: e-INFRA CZ - 90140; EATRIS-CZ IV - 90253; CIISB III - 90242
    Institutional support: RVO:61388971 ; RVO:86652036
    Keywords : acylated segment * adenylate cyclase toxin * cytotoxicity * hydrogen/deuterium exchange * RTX toxin * thermal stability * tryptophan residue * α-hemolysin * β integrins 2
    OECD category: Microbiology
    Impact factor: 4.8, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0021925823020069?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0344352
     
     
  5. 5.
    0564645 - BC 2024 RIV NL eng J - Journal Article
    Svobodová, Zdeňka - Skoková Habuštová, Oxana - Sehadová, Hana
    No bioaccumulation of Cry protein in the aphidophagous predator Harmonia axyridis.
    Environmental Toxicology and Pharmacology. Roč. 97, JAN 01 (2023), č. článku 104015. ISSN 1382-6689. E-ISSN 1872-7077
    Institutional support: RVO:60077344
    Keywords : toxin uptake * toxin accumulation * Cry protein
    OECD category: Agronomy, plant breeding and plant protection
    Impact factor: 4.3, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S1382668922002083?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0349820
     
     
  6. 6.
    0563496 - MBÚ 2023 RIV US eng J - Journal Article
    Holubová, Jana - Staněk, Ondřej - Juhasz, Attila - Soumana, I. H. - Makovický, Peter - Šebo, Peter
    The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.
    PLoS Pathogens. Roč. 18, č. 4 (2022), č. článku e1010402. ISSN 1553-7366. E-ISSN 1553-7374
    R&D Projects: GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) LM2018126; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
    Research Infrastructure: EATRIS-CZ III - 90133; CCP II - 90126
    Institutional support: RVO:61388971 ; RVO:68378050
    Keywords : adenylate-cyclase toxin * serum antibody-responses * neutrophil recruitment * confers resistance * baboon model * whole-cell * antigen * vaccine * colonization * protection
    OECD category: Microbiology; Microbiology (UMG-J)
    Impact factor: 6.7, year: 2022
    Method of publishing: Open access
    https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010402
    Permanent Link: https://hdl.handle.net/11104/0335454
     
     
  7. 7.
    0562934 - ÚMG 2023 RIV US eng J - Journal Article
    Klímová, M. - Holubová, J. - Streparola, Gaia - Tomala, J. - Brazdilova, L. - Staněk, O. - Bumba, L. - Šebo, P.
    Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes.
    PLoS Pathogens. Roč. 18, č. 6 (2022), č. článku e1010577. ISSN 1553-7366. E-ISSN 1553-7374
    R&D Projects: GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045; GA MŠMT(CZ) LM2018126; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:68378050
    Keywords : Adenylate-cyclase toxin * respiratory-tract colonization * Bordetella-pertissis * neutrophil recruitment * antigen presentation * ADP-ribosylation * immune-response * RTX proteins * in vitro * infection
    OECD category: Virology
    Impact factor: 6.7, year: 2022
    Method of publishing: Open access
    https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010577
    Permanent Link: https://hdl.handle.net/11104/0336324
     
     
  8. 8.
    0562903 - MBÚ 2023 RIV CH eng J - Journal Article
    Golshani, Maryam - Rahman, Waheed Ur - Osičková, Adriana - Holubová, Jana - Lora, J. - Balashova, N. - Šebo, Peter - Osička, Radim
    Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the β2 Integrin CD11b/CD18.
    International Journal of Molecular Sciences. Roč. 23, č. 20 (2022), č. článku 12598. E-ISSN 1422-0067
    R&D Projects: GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) LX22NPO5103
    Institutional support: RVO:61388971
    Keywords : adenylate cyclase toxin * Bordetella pertussis * CD11b/CD18 * filamentous hemagglutinin * heparin * integrin
    OECD category: Microbiology
    Impact factor: 5.6, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/23/20/12598
    Permanent Link: https://hdl.handle.net/11104/0335072
    FileDownloadSizeCommentaryVersionAccess
    Filamentous Hemagglutinin.pdf04.2 MBPublisher’s postprintopen-access
     
     
  9. 9.
    0562673 - MBÚ 2023 RIV US eng J - Journal Article
    Klímová, Nela - Holubová, Jana - Streparola, Gaia - Tomala, Jakub - Brázdilová, Ludmila - Staněk, Ondřej - Bumba, Ladislav - Šebo, Peter
    Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes.
    PLoS Pathogens. Roč. 18, č. 6 (2022), č. článku e1010577. ISSN 1553-7366. E-ISSN 1553-7374
    R&D Projects: GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA22-23578S; GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) ED1.1.00/02.0109
    Research Infrastructure: Czech-BioImaging II - 90129; EATRIS-CZ III - 90133
    Institutional support: RVO:61388971 ; RVO:86652036
    Keywords : adenylate-cyclase toxin * respiratory-tract colonization * bordetella-pertussis * neutrophil * recruitment * antigen presentation * adp-ribosylation * immune-response * rtx proteins * in-vitro * infection
    OECD category: Microbiology
    Impact factor: 6.7, year: 2022
    Method of publishing: Open access
    https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010577
    Permanent Link: https://hdl.handle.net/11104/0334929
     
     
  10. 10.
    0559717 - ÚMG 2023 RIV CH eng J - Journal Article
    Malandra, A. - Rahman, W.U. - Klímová, N. - Streparola, Gaia - Holubová, J. - Osičková, A. - Bariselli, Simone - Šebo, P. - Osička, R.
    Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein.
    International Journal of Molecular Sciences. Roč. 22, č. 16 (2021), č. článku 9064. E-ISSN 1422-0067
    R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT EF18_046/0015861
    Institutional support: RVO:68378050
    Keywords : adenylate cyclase toxin * Bordetella * cAMP * creb * epithelium * mucin * pertussis toxin
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.208, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/22/16/9064
    Permanent Link: https://hdl.handle.net/11104/0332926
     
     

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