Search results
- 1.0510161 - BFÚ 2020 US eng J - Journal Article
Malina, Jaroslav - Čechová, Klára - Farrell, N.P. - Brabec, Viktor
Substitution-Inert Polynuclear Platinum Complexes with Dangling Amines: Condensation/Aggregation of Nucleic Acids and Inhibition of DNA-Related Enzymatic Activities.
Inorganic Chemistry. Roč. 58, č. 10 (2019), s. 6804-6810. ISSN 0020-1669. E-ISSN 1520-510X
Keywords : transcriptional activity * topoisomerase-i * phosphate clamp * molecules * enhancement
Impact factor: 4.825, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.inorgchem.9b00254
Permanent Link: http://hdl.handle.net/11104/0300706 - 2.0447649 - BFÚ 2016 RIV DE eng J - Journal Article
Malina, Jaroslav - Hannon, M.J. - Brabec, Viktor
Iron(II) Supramolecular Helicates Condense Plasmid DNA and Inhibit Vital DNA-Related Enzymatic Activities.
Chemistry - A European Journal. Roč. 21, č. 31 (2015), s. 11189-11195. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA13-08273S
Institutional support: RVO:68081707
Keywords : TOPOISOMERASE-I * METALLOSUPRAMOLECULAR CYLINDERS * TRANSCRIPTIONAL ACTIVITY
Subject RIV: BO - Biophysics
Impact factor: 5.771, year: 2015
Permanent Link: http://hdl.handle.net/11104/0249456 - 3.0427970 - BFÚ 2015 RIV GB eng J - Journal Article
Plšíková, J. - Štěpánková, Jana - Kašpárková, Jana - Brabec, Viktor - Bačkor, M. - Kozurková, M.
Lichen secondary metabolites as DNA-interacting agents.
Toxicology in Vitro. Roč. 28, č. 2 (2014), s. 182-186. ISSN 0887-2333. E-ISSN 1879-3177
Institutional support: RVO:68081707
Keywords : Lichens * DNA-binding * Topoisomerase I, II
Subject RIV: BO - Biophysics
Impact factor: 2.903, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233410 - 4.0332052 - BFÚ 2010 RIV GB eng J - Journal Article
Malina, Jaroslav - Vrána, Oldřich - Brabec, Viktor
Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional Pt-II complexes.
[Mechanistická studie modulace štěpící aktivity topoisomerázy I vlivem mono- a bifunkčních aduktů platnatých komplexů na DNA.]
Nucleic Acids Research. Roč. 37, č. 16 (2009), s. 5432-5442. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) LC06030; GA MŠMT(CZ) ME08017; GA MŠMT(CZ) OC08003; GA AV ČR(CZ) 1QS500040581; GA AV ČR(CZ) KAN200200651; GA AV ČR(CZ) IAA400040803
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : cisplatin * camptothecin * topoisomerase I
Subject RIV: BO - Biophysics
Impact factor: 7.479, year: 2009
Permanent Link: http://hdl.handle.net/11104/0177406 - 5.0311314 - BFÚ 2009 PL eng A - Abstract
Malina, Jaroslav - Brabec, Viktor
Effect of DNA modification by platinum complexes on topoisomerase I cleavage activity.
[Vliv modifikace DNA platinovými komplexy na štěpící aktivitu topoisomerázy.]
Abstract Book. Wroclaw, 2008. s. 239. ISBN 978-83-60043-10-3.
[9th European Biological Inorganic Chemistry Conference. 02.09.2008-06.09.2008, Wroclaw]
R&D Projects: GA AV ČR(CZ) KJB400040601
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040507
Keywords : topoisomerase I activity * platinum complexes * DNA
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0162957 - 6.0126586 - BFU-R 20013146 CZ cze K - Conference Paper (Czech conference)
Prokop, Radim - Vrána, Oldřich - Brabec, Viktor
Protinádorově účinné platinové komplexy jako inhibitory DNA topoizomerázy I.
[The antitumor platinum complexes as inhibitors of DNA topoisomerase I.]
SBORNÍK ABSTRAKT. Olomouc: Univerzita Palackého, 2001, s. 11.
[Biologické dny /16./. Aktuální téma z buněčné a molekulární biologie. Olomouc (CZ), 05.09.2001-07.09.2001]
R&D Projects: GA AV ČR IAA7004805; GA MZd NL6069
Institutional research plan: CEZ:AV0Z5004920
Keywords : antitumor platinum * DNA topoisomerase I
Subject RIV: BO - Biophysics
Permanent Link: http://hdl.handle.net/11104/0024814