Search results
- 1.0541994 - BFÚ 2022 RIV GB eng J - Journal Article
Hýžd'alová, M. - Procházková, J. - Strapáčová, S. - Svrzkova, L. - Vacek, Ondřej - Fedr, Radek - Andrysik, Z. - Hrubá, E. - Líbalová, Helena - Kléma, J. - Topinka, Jan - Mašek, J. - Souček, Karel - Vondráček, Jan - Machala, M.
A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
Chemosphere. Roč. 263, JAN 2021 (2021), č. článku 128126. ISSN 0045-6535. E-ISSN 1879-1298
Institutional support: RVO:68081707 ; RVO:68378041
Keywords : aryl-hydrocarbon receptor * polycyclic aromatic-hydrocarbons * tgf-beta * a549 cells * cigarette-smoking
OECD category: Cell biology; Cell biology (UEM-P)
Impact factor: 8.943, year: 2021
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0045653520323213?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0319497 - 2.0517769 - MBÚ 2020 RIV US eng J - Journal Article
Michalcová, K. - Roychoudhury, S. - Halenar, M. - Tvrdá, E. - Kovačíková, E. - Vašíček, J. - Chrenek, P. - Baldovská, S. - Sanislo, L. - Křen, Vladimír - Kolesárová, A.
In vitro response of human ovarian cancer cells to dietary bioflavonoid isoquercitrin.
Journal of Environmental Science and Health Part B-Pesticides Food Contaminants and Agricultural Wastes. Roč. 54, č. 9 (2019), s. 752-757. ISSN 0360-1234. E-ISSN 1532-4109
R&D Projects: GA ČR(CZ) GA18-00150S
Institutional support: RVO:61388971
Keywords : Isoquercitrin * ovarian cancer * TGF-beta 1
OECD category: Biochemistry and molecular biology
Impact factor: 1.697, year: 2019
Method of publishing: Limited access
https://www.tandfonline.com/doi/full/10.1080/03601234.2019.1633214
Permanent Link: http://hdl.handle.net/11104/0303175 - 3.0502505 - BFÚ 2019 RIV CZ eng J - Journal Article
Hofer, Michal - Hoferová, Zuzana - Remšík, Jan - Nováková, M. - Procházková, J. - Fedr, Radek - Kohoutek, J. - Dušek, L. - Hampl, A. - Souček, Karel
Hematological Findings in Non-Treated and gamma-Irradiated Mice Deficient for MIC-1/GDF15.
Physiological Research. Roč. 67, č. 4 (2018), s. 623-636. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA15-11707S; GA ČR(CZ) GA16-12454S; GA MZd(CZ) NV15-28628A; GA MZd(CZ) NV15-33999A
Institutional support: RVO:68081707
Keywords : tgf-beta superfamily * differentiation factor 15 * factor-binding sites * transcription factors
OECD category: Physiology (including cytology)
Impact factor: 1.701, year: 2018
Permanent Link: http://hdl.handle.net/11104/0294426 - 4.0495178 - BFÚ 2019 RIV US eng J - Journal Article
Souček, Karel - Malenovská, A. - Kahounová, Zuzana - Remšík, Jan - Holubcová, Z. - Soukup, T. - Kurfurstová, A. - Bouchal, J. - Suchánková, Tereza - Slabáková, Eva - Hampl, A.
Presence of growth/differentiation factor-15 cytokine in human follicular fluid, granulosa cells, and oocytes.
Journal of Assisted Reproduction and Genetics. Roč. 35, č. 8 (2018), s. 1407-1417. ISSN 1058-0468. E-ISSN 1573-7330
R&D Projects: GA ČR(CZ) GA15-11707S; GA MZd(CZ) NV15-33999A; GA MŠMT 7AMB16AT022; GA MŠMT(CZ) EE2.3.30.0030
Institutional support: RVO:68081707
Keywords : tgf-beta superfamily * differentiation factor 15 * macrophage inhibitory cytokine * in-vitro fertilization * proteomic analysis * oxidative stress * cancer cells * growth * gdf15 * activation
OECD category: Genetics and heredity (medical genetics to be 3)
Impact factor: 2.820, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288186 - 5.0481982 - ÚMG 2018 RIV US eng J - Journal Article
Burrows, K. - Antignano, F. - Bramhall, M. - Chenery, A. - Scheer, S. - Kořínek, Vladimír - Underhill, T. M. - Zaph, C.
The transcriptional repressor HIC1 regulates intestinal immune homeostasis.
Mucosal Immunology. Roč. 10, č. 6 (2017), s. 1518-1528. ISSN 1933-0219. E-ISSN 1935-3456
Institutional support: RVO:68378050
Keywords : cd4(+) t-cells * anti-interleukin-17 monoclonal-antibody * cd103(+) dendritic cells * acid receptor-alpha * retinoic acid * t(h)17 cells * target genes * double-blind * tgf-beta * differentiation
OECD category: Biochemistry and molecular biology
Impact factor: 7.360, year: 2017
Permanent Link: http://hdl.handle.net/11104/0277402 - 6.0476344 - ÚEB 2018 RIV FR eng J - Journal Article
Řezníčková, Eva - Tenora, L. - Pospíšilová, Pavlína - Galeta, J. - Jorda, Radek - Berka, K. - Majer, Pavel - Potáček, M. - Kryštof, Vladimír
ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles.
European Journal of Medicinal Chemistry. Roč. 127, FEB 15 (2017), s. 632-642. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR(CZ) GA15-15264S; GA MŠMT(CZ) LM2015047
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : i-receptor kinase * beta signaling pathway * small-molecule inhibitor * tgf-beta * domain inhibitors * growth * fibrosis * cancer * potent * series * Transforming growth factor beta receptor I * Protein kinase * Inhibitor * Substituted pyrrolo[1,2-b]pyrazoles
OECD category: Pharmacology and pharmacy; Pharmacology and pharmacy (UOCHB-X)
Impact factor: 4.816, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272863File Download Size Commentary Version Access 2017_Reznickova_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_632.pdf 4 1.3 MB Other open-access - 7.0472044 - ÚMG 2017 RIV US eng J - Journal Article
Janečková, Lucie - Kolář, Michal - Švec, Jiří - Láníková, Lucie - Pospíchalová, Vendula - Baloghová, Nikol - Vojtěchová, Martina - Šloncová, Eva - Strnad, Hynek - Kořínek, Vladimír
HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.
Translational Oncology. Roč. 9, č. 2 (2016), s. 99-107. ISSN 1944-7124. E-ISSN 1936-5233
R&D Projects: GA ČR GAP305/12/2347; GA MŠMT LO1419; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : direct target gene * cancer 1 hic1 * colorectal-cancer * breast-cancer * lung-cancer * tgf-beta * methylation * hypermethylation * subtypes * cells
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.025, year: 2016
Permanent Link: http://hdl.handle.net/11104/0269388 - 8.0468499 - ÚEB 2017 RIV US eng J - Journal Article
Tenora, L. - Galeta, J. - Řezníčková, Eva - Kryštof, Vladimír - Potáček, M.
Application of Pd-Catalyzed Cross-Coupling Reactions in the Synthesis of 5,5-Dimethy1-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles that Inhibit ALK5 Kinase.
Journal of Organic Chemistry. Roč. 81, č. 23 (2016), s. 11841-11856. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA15-15264S
Institutional support: RVO:61389030
Keywords : c-h functionalization * pyridine n-oxides * receptor-type-i * direct arylation * tgf-beta * galunisertib ly2157299 * domain inhibitors * bond activation * growth * withasomnine
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 4.849, year: 2016
Permanent Link: http://hdl.handle.net/11104/0266335File Download Size Commentary Version Access 2016_Tenora_JOURNAL OF ORGANIC CHEMISTRY_11841.pdf 0 2.4 MB Other open-access - 9.0441230 - ÚMG 2015 RIV US eng J - Journal Article
Hubáčková, Soňa - Krejčíková, Kateřina - Bártek, Jiří - Hodný, Zdeněk
IL1-and TGF beta-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine 'Bystander senescence'.
Aging. Roč. 4, č. 12 (2012), 932-951. ISSN 1945-4589
R&D Projects: GA ČR GA204/08/1418; GA ČR GAP301/10/1525
Institutional support: RVO:68378050
Keywords : senescence-associated secretome * DNA damage response * cytokines * JAK/STAT3 * TGF beta * NF kappa B * IL6 * IL beta * Nox4 * autocrine and paracrine signaling * tumor
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.696, year: 2012
Permanent Link: http://hdl.handle.net/11104/0244280File Download Size Commentary Version Access 0441230.pdf 5 3 MB Publisher’s postprint require - 10.0435856 - ÚMG 2015 RIV DE eng J - Journal Article
Kosla, Jan - Dvořáková, Marta - Dvořák, Michal - Čermák, Vladimír
Effective myofibroblast dedifferentiation by concomitant inhibition of TGF-beta signaling and perturbation of MAPK signaling.
European Journal of Cell Biology. Roč. 92, č. 12 (2013), s. 363-373. ISSN 0171-9335. E-ISSN 1618-1298
R&D Projects: GA AV ČR KAN200520801
Institutional support: RVO:68378050
Keywords : PDGFB * Ha-Ras(G12V) * EGR4 * TGF-beta * Myofibroblast * FOXG1 * Microarrays
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.699, year: 2013
Permanent Link: http://hdl.handle.net/11104/0241975File Download Size Commentary Version Access 0435856.pdf 5 4.5 MB Publisher’s postprint require