Search results
- 1.0561212 - FZÚ 2023 RIV US eng J - Journal Article
Nepovímová, E. - Svobodová, L. - Doležal, R. - Rostohar, Danijela … Total 30 authors
Tacrine – benzothiazoles: novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems.
Bioorganic Chemistry. Roč. 107, Feb (2021), č. článku 104596. ISSN 0045-2068. E-ISSN 1090-2120
EU Projects: European Commission(XE) 654148 - LASERLAB-EUROPE
Institutional support: RVO:68378271
Keywords : Alzheimer's disease * tacrine * benzothiazole * acetylcholinesterase Inhibitors * amyloid beta * ABAD * MTDLs
OECD category: Optics (including laser optics and quantum optics)
Impact factor: 5.307, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.bioorg.2020.104596
Permanent Link: https://hdl.handle.net/11104/0333898 - 2.0551558 - ÚEM 2022 RIV FR eng J - Journal Article
Gorecki, L. - Misiachna, Anna - Damborský, J. - Doležal, R. - Korábečný, J. - Čejková, L. - Hakenová, K. - Chvojková, M. - Zdarová Karasová, J. - Prchal, L. - Novák, M. - Kolcheva, Marharyta - Kortus, Štěpán - Valeš, K. - Horák, Martin - Soukup, O.
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-D-Aspartate receptors.
European Journal of Medicinal Chemistry. Roč. 219, 5 july (2021), č. článku 113434. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA20-12047S; GA TA ČR(CZ) TO01000078
Institutional support: RVO:68378041
Keywords : QSAR * acetylcholinesterase * electrophysiology * glutamate receptor * ion channel * pharmacologyin vivo * tacrine
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113434
Permanent Link: http://hdl.handle.net/11104/0326821 - 3.0542659 - FGÚ 2022 RIV FR eng J - Journal Article
Gorecki, L. - Misiachna, Anna - Damborský, J. - Doležal, R. - Korábečný, J. - Čejková, L. - Hakenová, K. - Chvojková, M. - Zdarová Karasová, J. - Prchal, L. - Novák, M. - Kolcheva, Marharyta - Kortus, Štěpán - Valeš, K. - Horák, Martin - Soukup, O.
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
European Journal of Medicinal Chemistry. Roč. 219, 5 July (2021), č. článku 113434. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823
Keywords : QSAR * acetylcholinesterase * electrophysiology * glutamate receptor * ion channel * pharmacology * in vivo * tacrine
OECD category: Pharmacology and pharmacy
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113434
Permanent Link: http://hdl.handle.net/11104/0320032 - 4.0541456 - ÚOCHB 2022 RIV CH eng J - Journal Article
Konkoľová, Eva - Hudáčová, M. - Hamuľaková, S. - Jendželovský, R. - Vargová, J. - Ševc, J. - Fedoročko, P. - Kožurková, M.
Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.
Molecules. Roč. 26, č. 4 (2021), č. článku 1133. E-ISSN 1420-3049
Institutional support: RVO:61388963
Keywords : A549 * DNA * cytotoxicity * lung carcinoma cells * tacrine-coumarin derivatives * topoisomerases I, II
OECD category: Biochemistry and molecular biology
Impact factor: 4.927, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/molecules26041133
Permanent Link: http://hdl.handle.net/11104/0319006 - 5.0504524 - FGÚ 2020 RIV FR eng J - Journal Article
Chalupová, K. - Korábečný, J. - Bartolini, M. - Monti, B. - Lamba, D. - Caliandro, R. - Pesaresi, A. - Brazzolotto, X. - Gastellier, A.-J. - Nachon, F. - Pejchal, J. - Jarošová, M. - Hepnarová, V. - Jun, D. - Hrabinová, M. - Doležal, R. - Zdarová Karasová, J. - Mžik, M. - Krištofíková, Z. - Misík, J. - Mucková, L. - Jošt, P. - Soukup, O. - Benková, M. - Setnička, V. - Habartová, L. - Chvojková, Markéta - Kletečková, Lenka - Valeš, Karel - Mezeiová, E. - Uliassi, E. - Vališ, M. - Nepovímová, E. - Bolognesi, M. L. - Kuča, K.
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
European Journal of Medicinal Chemistry. Roč. 168, Apr 15 (2019), s. 491-514. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:67985823
Keywords : multi-target directed ligands * Alzheimer's disease * tacrine-tryptophan hybrids * acetylcholinesterase
OECD category: Neurosciences (including psychophysiology
Impact factor: 5.573, year: 2019
Method of publishing: Limited access
https://doi.org/10.1016/j.ejmech.2019.02.021
Permanent Link: http://hdl.handle.net/11104/0296178 - 6.0474134 - FGÚ 2018 RIV US eng J - Journal Article
Horák, Martin - Holubová, K. - Nepovímová, E. - Krůšek, Jan - Kaniaková, Martina - Korábečný, J. - Vyklický ml., Ladislav - Kuča, K. - Stuchlík, Aleš - Říčný, J. - Valeš, K. - Soukup, O.
The pharmacology of tacrine at N-methyl-D-aspartate receptors.
Progress in Neuro-Psychopharmacology & Biological Psychiatry. Roč. 75, Apr 3 (2017), s. 54-62. ISSN 0278-5846. E-ISSN 1878-4216
R&D Projects: GA ČR(CZ) GA16-08554S
Institutional support: RVO:67985823
Keywords : tacrine * NMDA receptors * long term potentiation * cognition * M1 activation * multi-target directed ligands
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.185, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271246