Search results
- 1.0585591 - MBÚ 2025 RIV GB eng J - Journal Article
Dostál, Z. - Zholobenko, A. V. - Přichystalová, H. - Gottschalk, B. - Valentová, Kateřina - Malli, R. - Modrianský, M.
Quercetin protects cardiomyoblasts against hypertonic cytotoxicity by abolishing intracellular CaSUP2+/SUP elevations and mitochondrial depolarisation.
Biochemical Pharmacology. Roč. 222, April 2024 (2024), č. článku 116094. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA23-04654S
Institutional support: RVO:61388971
Keywords : calcium * 2,3-dehydrosilybin * polyphenols * flavonoids * silymarin * apoptosis * injury * Hypertonic stress * Quercetin * 2,3-dehydrosilybin * H9c2 cells * Calcium
OECD category: Pharmacology and pharmacy
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0006295224000777?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0353287 - 2.0578183 - MBÚ 2024 RIV cze P - Patent Document
Viktorová, J. - Křen, Vladimír - Holasová, K. - Macek, T. - Valentová, Kateřina - Biedermann, David - Dobiasová, S.
Farmaceutický přípravek pro léčbu lékově rezistentních bakteriálních infekcí.
[A pharmaceutical preparation for the treatment of drug-resistant bacterial infections.]
2023. Owner: Vysoká škola chemicko-technologická v Praze, Mikrobiologický ústav AV ČR, v. v. i. Date of the patent acceptance: 27.09.2023. Patent Number: 309821. Territorial Protection: národní patent v členském státě EU .
R&D Projects: GA MŠMT(CZ) LUC23061; GA ČR GA21-00551S; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388971
Keywords : 2,3-dehydrosilybin * silymarin * drug-resistant * infection * antibiotic
OECD category: Pharmacology and pharmacy
https://isdv.upv.cz/doc/FullFiles/Patents/FullDocuments/309/309821.pdf
Permanent Link: https://hdl.handle.net/11104/0347227File Download Size Commentary Version Access Patent 309821 2023.pdf 4 590.4 KB Other open-access - 3.0575447 - ÚIACH 2024 RIV DE eng J - Journal Article
Pluháčková, H. - Kudláčková, Barbora - Svojanovská, Lenka - Roth, Michal - Bradáčová, M. - Bjelková, M.
Effect of Field Trial on Silymarin Complex Composition and Antioxidant Assessment of Milk Thistle (Silybum marianum L. Gaertner).
Plant Foods for Human Nutrition. Roč. 78, č. 4 (2023), s. 691-697. ISSN 0921-9668. E-ISSN 1573-9104
Institutional support: RVO:68081715
Keywords : Silybum marianum L. * silymarin complex * row width
OECD category: Analytical chemistry
Impact factor: 4, year: 2022
Method of publishing: Limited access
Permanent Link: https://hdl.handle.net/11104/0345232File Download Size Commentary Version Access 0575447.pdf 1 750.9 KB Publisher’s postprint require - 4.0561705 - ÚIACH 2023 RIV CZ eng C - Conference Paper (international conference)
Fojtíková, L. - Bradáčová, M. - Kudláčková, Barbora - Bjelková, M. - Pluháčková, H.
The effect of milk thistle cultivation technology [Silybum marianum (L.) Gaertner] on the yield and contained compounds.
MendelNet 2021: Proceedings of 28th International PhD Students Conference. Brno: Mendel University in Brno, 2021 - (Cerkal, R.; Březinová Belcredi, N.; Prokešová, L.), s. 25-30. ISBN 978-80-7509-821-4.
[MendelNet 2021, Brno, 2021/11/10-2021/11/10, Mendelova univerzita. Brno (CZ), 10.11.2021-10.11.2021]
Institutional support: RVO:68081715
Keywords : milk thistle * cultivation technology * silymarin complex
OECD category: Analytical chemistry
https://mnet.mendelu.cz/mendelnet2021/mnet_2021_full.pdf
Permanent Link: https://hdl.handle.net/11104/0334221File Download Size Commentary Version Access 0561705.pdf 3 220.8 KB Author’s postprint open-access - 5.0558662 - MBÚ 2023 RIV GB eng J - Journal Article
Křen, Vladimír - Valentová, Kateřina
Silybin and its congeners: from traditional medicine to molecular effects.
Natural Product Reports. Roč. 39, č. 6 (2022), s. 1264-1281. ISSN 0265-0568. E-ISSN 1460-4752
R&D Projects: GA ČR GA21-00551S; GA MŠMT(CZ) LTC20070
EU Projects: European Commission(CZ) CA17104 - STRATAGEM
Institutional support: RVO:61388971
Keywords : milk thistle * silymarin flavonolignans * in-vitro * silibinin * silychristin * isosilybin * 2,3-dehydrosilybin * diastereoisomers * identification * derivatives
OECD category: Medicinal chemistry
Impact factor: 11.9, year: 2022
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2022/NP/D2NP00013J
Permanent Link: https://hdl.handle.net/11104/0332537 - 6.0554370 - ÚMG 2022 RIV CH eng J - Journal Article
Bechyňská, K. - Kosek, V. - Fenclová, M. - Muchová, L. - Smid, V. - Suk, J. - Chalupský, Karel - Sticová, E. - Hůrková, K. - Hajslova, J. - Vítek, L. - Stranská, M.
The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease.
Biomolecules. Roč. 11, č. 11 (2021), č. článku 1723. E-ISSN 2218-273X
R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : mycotoxins * silymarin * lipidome * metabolome * mice liver * mass spectrometry
OECD category: Biochemistry and molecular biology
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/11/1723
Permanent Link: http://hdl.handle.net/11104/0328990 - 7.0547159 - MBÚ 2022 RIV CH eng J - Journal Article
Křen, Vladimír
Chirality Matters: Biological Activity of Optically Pure Silybin and Its Congeners.
International Journal of Molecular Sciences. Roč. 22, č. 15 (2021), č. článku 7885. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-01799S
Institutional support: RVO:61388971
Keywords : silymarin * silybin * Silybum marianum * milk thistle * diastereomer * chirality * isosilybin * silychristin * silydianin * silibinin * flavonolignan * flavonoid * dehydroflavonolignan
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/15/7885
Permanent Link: http://hdl.handle.net/11104/0323482 - 8.0547149 - MBÚ 2022 RIV CH eng J - Journal Article
Biedermann, David - Hurtová, Martina - Benada, Oldřich - Valentová, Kateřina - Biedermannová, Lada - Křen, Vladimír
Continuous diastereomeric kinetic resolution—silybins a and b.
Catalysts. Roč. 11, č. 9 (2021), č. článku 1106. E-ISSN 2073-4344
R&D Projects: GA MŠMT(CZ) LTC18071; GA ČR GA21-00551S
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : Silybin * Silybum marianum * Silymarin * milk thistle * lipase * Novozym 435 * diastereomers * resolution * flow reaction
OECD category: Organic chemistry; Physical chemistry (BTO-N)
Impact factor: 4.501, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2073-4344/11/9/1106
Permanent Link: http://hdl.handle.net/11104/0323472 - 9.0543851 - MBÚ 2022 RIV GB eng J - Journal Article
Biedermann, David - Hurtová, Martina - Biedermannová, Lada - Valentová, Kateřina - Křen, Vladimír
Flavonolignans from silymarin do not intercalate into DNA: Rebuttal of data published in the paper J. Mol. Recognit. e2812 (2019).
Journal of Molecular Recognition. Roč. 34, č. 7 (2021), č. článku 2888. ISSN 0952-3499. E-ISSN 1099-1352
R&D Projects: GA MŠMT(CZ) LTC18071
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : Flavonolignans * silymarin
OECD category: Medicinal chemistry; Biophysics (BTO-N)
Impact factor: 2.891, year: 2021
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/abs/10.1002/jmr.2888
Permanent Link: http://hdl.handle.net/11104/0320966 - 10.0543091 - MBÚ 2022 RIV CH eng J - Journal Article
Lomozová, Z. - Tvrdý, V. - Hrubša, M. - Catapano, M.C. - Macáková, K. - Biedermann, David - Kučera, R. - Křen, Vladimír - Mladěnka, P. - Valentová, Kateřina
Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo.
Antioxidants. Roč. 10, č. 5 (2021), č. článku 679. E-ISSN 2076-3921
R&D Projects: GA ČR(CZ) GA18-00121S
Institutional support: RVO:61388971
Keywords : flavonolignans * silymarin * milk thistle * dehydroflavonolignans * dehydrosilybin * dehydrosilychristin * hydroxyl radical * iron * copper * prooxidation
OECD category: Microbiology
Impact factor: 7.675, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3921/10/5/679
Permanent Link: http://hdl.handle.net/11104/0320379