Search results
- 1.0570600 - ÚŽFG 2024 RIV GB eng J - Journal Article
Lněničková, K. - Vrba, J. - Kosina, P. - Papoušková, B. - Mekadim, Chahrazed - Mrázek, Jakub - Sova, M. - Sovová, E. - Valentová, Kateřina - Křen, Vladimír - Kouřilová, P. - Vrbková, J. - Ulrichová, J.
Metabolic profiling of silymarin constituents in urine and feces of healthy volunteers: A 90-day study.
Journal of Functional Foods. Roč. 100, Jan 23 (2023), č. článku 105391. ISSN 1756-4646. E-ISSN 2214-9414
R&D Projects: GA ČR(CZ) GA18-00132S; GA ČR GA21-00551S; GA MŠMT(CZ) LTC19039
Institutional support: RVO:67985904 ; RVO:61388971
Keywords : flavonolignans * silybin * taxifolin
OECD category: Microbiology; Pharmacology and pharmacy (MBU-M)
Impact factor: 5.6, year: 2022
Method of publishing: Limited access
https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=37782471041
Permanent Link: https://hdl.handle.net/11104/0341904 - 2.0557995 - MBÚ 2023 RIV CH eng J - Journal Article
Petrásková, Lucie - Káňová, Kristýna - Brodsky, Katerina - Hetman, Anastasia - Petránková, Barbora - Pelantová, Helena - Křen, Vladimír - Valentová, Kateřina
Sulfated Phenolic Substances: Preparation and Optimized HPLC Analysis.
International Journal of Molecular Sciences. Roč. 23, č. 10 (2022), č. článku 5743. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-00043S; GA MZd(CZ) NU21-02-00135
Institutional support: RVO:61388971
Keywords : enzymatic sulfation * quercetin * sulfotransferases * silybin * flavonolignans * metabolites * flavonoids * aryl sulfotransferase * Desulfitobacterium hafniense * HPLC analysis * sulfates * flavonoids * polyphenols * phenolic acid
OECD category: Analytical chemistry
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/10/5743
Permanent Link: http://hdl.handle.net/11104/0332217 - 3.0557462 - MBÚ 2023 RIV FR eng J - Journal Article
Holasová, K. - Křížkovská, B. - Hoang, L. - Dobiasová, S. - Lipov, J. - Macek, T. - Křen, Vladimír - Valentová, Kateřina - Ruml, T. - Viktorová, J.
Flavonolignans from silymarin modulate antibiotic resistance and virulence in Staphylococcus aureus.
Biomedicine & Pharmacotherapy. Roč. 149, May 2022 (2022), č. článku 112806. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA MŠMT(CZ) LTC20070; GA ČR GA21-00551S
Institutional support: RVO:61388971
Keywords : nora efflux pump * multidrug-resistance * ampicillin-sulbactam * biofilm formation * pcr assay * silibinin * expression * vitro * antibacterial * derivatives * Flavonolignans * Silybin * Silychristin * Multidrug resistance * Staphylococcus aureus * Efflux pump
OECD category: Pharmacology and pharmacy
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0753332222001949?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0331460 - 4.0557085 - MBÚ 2023 RIV CH eng J - Journal Article
Kosina, P. - Ryšavá, A. - Vostálová, J. - Papoušková, B. - Biedermann, David - Ulrichová, J. - Svobodová, A.
Stability and ultraviolet A photostability of silymarin polyphenols and its consequences for practical use in dermatology.
Journal of Photochemistry and Photobiology A-Chemistry. Roč. 429, 1 August (2022), č. článku 113897. ISSN 1010-6030. E-ISSN 1873-2666
Institutional support: RVO:61388971
Keywords : milk thistle * quercetin * oxidation * flavonoids * mechanisms * silybin * Silybum marianum * Flavonolignan * Flavonoid * Stability * Photostability * Photodecomposition products
OECD category: Dermatology and venereal diseases
Impact factor: 4.3, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S1010603022001265?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0331254 - 5.0550096 - MBÚ 2022 RIV CH eng J - Journal Article
Tvrdý, V. - Hrubša, M. - Jirkovský, E. - Biedermann, David - Kutý, M. - Valentová, Kateřina - Křen, Vladimír - Mladěnka, P.
Silymarin dehydroflavonolignans chelate zinc and partially inhibit alcohol dehydrogenase.
Nutrients. Roč. 13, č. 12 (2021), č. článku 4238. E-ISSN 2072-6643
R&D Projects: GA ČR(CZ) GA18-00121S
Institutional support: RVO:61388971
Keywords : Alcohol dehydrogenase * Chelation * Dehydrosilybin * Docking * Flavonolignans * Glutamate dehydrogenase * Silybin * Zinc
OECD category: Biochemistry and molecular biology
Impact factor: 6.706, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2072-6643/13/12/4238
Permanent Link: http://hdl.handle.net/11104/0325947 - 6.0547159 - MBÚ 2022 RIV CH eng J - Journal Article
Křen, Vladimír
Chirality Matters: Biological Activity of Optically Pure Silybin and Its Congeners.
International Journal of Molecular Sciences. Roč. 22, č. 15 (2021), č. článku 7885. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-01799S
Institutional support: RVO:61388971
Keywords : silymarin * silybin * Silybum marianum * milk thistle * diastereomer * chirality * isosilybin * silychristin * silydianin * silibinin * flavonolignan * flavonoid * dehydroflavonolignan
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/15/7885
Permanent Link: http://hdl.handle.net/11104/0323482 - 7.0547158 - MBÚ 2022 RIV CH eng J - Journal Article
Vrba, J. - Papoušková, B. - Lněničková, K. - Kosina, P. - Křen, Vladimír - Ulrichová, J.
Metabolism of 2,3-Dehydrosilybin A and 2,3-Dehydrosilybin B: A Study with Human Hepatocytes and Recombinant UDP-Glucuronosyltransferases and Sulfotransferases.
Antioxidants. Roč. 10, č. 6 (2021), č. článku 954. E-ISSN 2076-3921
R&D Projects: GA ČR GA21-00551S
Institutional support: RVO:61388971
Keywords : dehydrosilybin * silybin * metabolism * glucuronidation * sulfation * UDP-glucuronosyltransferase * sulfotransferase
OECD category: Biochemistry and molecular biology
Impact factor: 7.675, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3921/10/6/954
Permanent Link: http://hdl.handle.net/11104/0323480 - 8.0547149 - MBÚ 2022 RIV CH eng J - Journal Article
Biedermann, David - Hurtová, Martina - Benada, Oldřich - Valentová, Kateřina - Biedermannová, Lada - Křen, Vladimír
Continuous diastereomeric kinetic resolution—silybins a and b.
Catalysts. Roč. 11, č. 9 (2021), č. článku 1106. E-ISSN 2073-4344
R&D Projects: GA MŠMT(CZ) LTC18071; GA ČR GA21-00551S
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : Silybin * Silybum marianum * Silymarin * milk thistle * lipase * Novozym 435 * diastereomers * resolution * flow reaction
OECD category: Organic chemistry; Physical chemistry (BTO-N)
Impact factor: 4.501, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2073-4344/11/9/1106
Permanent Link: http://hdl.handle.net/11104/0323472 - 9.0543521 - MBÚ 2022 RIV US eng J - Journal Article
Tvrdý, V. - Pourová, J. - Jirkovský, E. - Křen, Vladimír - Valentová, Kateřina - Mladěnka, P.
Systematic review of pharmacokinetics and potential pharmacokinetic interactions of flavonolignans from silymarin.
Medicinal Research Reviews. Roč. 41, č. 4 (2021), s. 2195-2246. ISSN 0198-6325. E-ISSN 1098-1128
R&D Projects: GA ČR(CZ) GA18-00121S
Institutional support: RVO:61388971
Keywords : absorption * excretion * interactions * metabolism * silybin
OECD category: Pharmacology and pharmacy
Impact factor: 12.388, year: 2021
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/abs/10.1002/med.21791
Permanent Link: http://hdl.handle.net/11104/0320713 - 10.0537121 - MBÚ 2021 RIV US eng J - Journal Article
Hurtová, Martina - Biedermann, David - Kuzma, Marek - Křen, Vladimír
Mild and Selective Method of Bromination of Flavonoids.
Journal of Natural Products. Roč. 83, č. 11 (2020), s. 3324-3331. ISSN 0163-3864. E-ISSN 1520-6025
R&D Projects: GA ČR(CZ) GA18-00150S; GA MŠMT(CZ) LTC20070
Institutional support: RVO:61388971
Keywords : Silybin * Flavonolignans * Silicristin
OECD category: Organic chemistry
Impact factor: 4.050, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.jnatprod.0c00655
Permanent Link: http://hdl.handle.net/11104/0314868