Search results
- 1.0558662 - MBÚ 2023 RIV GB eng J - Journal Article
Křen, Vladimír - Valentová, Kateřina
Silybin and its congeners: from traditional medicine to molecular effects.
Natural Product Reports. Roč. 39, č. 6 (2022), s. 1264-1281. ISSN 0265-0568. E-ISSN 1460-4752
R&D Projects: GA ČR GA21-00551S; GA MŠMT(CZ) LTC20070
EU Projects: European Commission(CZ) CA17104 - STRATAGEM
Institutional support: RVO:61388971
Keywords : milk thistle * silymarin flavonolignans * in-vitro * silibinin * silychristin * isosilybin * 2,3-dehydrosilybin * diastereoisomers * identification * derivatives
OECD category: Medicinal chemistry
Impact factor: 11.9, year: 2022
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2022/NP/D2NP00013J
Permanent Link: https://hdl.handle.net/11104/0332537 - 2.0557462 - MBÚ 2023 RIV FR eng J - Journal Article
Holasová, K. - Křížkovská, B. - Hoang, L. - Dobiasová, S. - Lipov, J. - Macek, T. - Křen, Vladimír - Valentová, Kateřina - Ruml, T. - Viktorová, J.
Flavonolignans from silymarin modulate antibiotic resistance and virulence in Staphylococcus aureus.
Biomedicine & Pharmacotherapy. Roč. 149, May 2022 (2022), č. článku 112806. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA MŠMT(CZ) LTC20070; GA ČR GA21-00551S
Institutional support: RVO:61388971
Keywords : nora efflux pump * multidrug-resistance * ampicillin-sulbactam * biofilm formation * pcr assay * silibinin * expression * vitro * antibacterial * derivatives * Flavonolignans * Silybin * Silychristin * Multidrug resistance * Staphylococcus aureus * Efflux pump
OECD category: Pharmacology and pharmacy
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0753332222001949?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0331460 - 3.0547159 - MBÚ 2022 RIV CH eng J - Journal Article
Křen, Vladimír
Chirality Matters: Biological Activity of Optically Pure Silybin and Its Congeners.
International Journal of Molecular Sciences. Roč. 22, č. 15 (2021), č. článku 7885. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-01799S
Institutional support: RVO:61388971
Keywords : silymarin * silybin * Silybum marianum * milk thistle * diastereomer * chirality * isosilybin * silychristin * silydianin * silibinin * flavonolignan * flavonoid * dehydroflavonolignan
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/15/7885
Permanent Link: http://hdl.handle.net/11104/0323482 - 4.0503924 - MBÚ 2020 RIV GB eng J - Journal Article
Šuk, J. - Jašprová, J. - Biedermann, David - Petrásková, Lucie - Valentová, Kateřina - Křen, Vladimír - Muchová, L. - Vítek, L.
Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice.
Oxidative Medicine and Cellular Longevity. Roč. 2019, č. 1 (2019), č. článku 6026902. ISSN 1942-0900. E-ISSN 1942-0994
R&D Projects: GA MZd(CZ) NV16-27317A
Institutional support: RVO:61388971
Keywords : serum bilirubin * intravenous silibinin * gilbert-syndrome
OECD category: Medicinal chemistry
Impact factor: 5.076, year: 2019
Method of publishing: Open access
https://www.hindawi.com/journals/omcl/2019/6026902/
Permanent Link: http://hdl.handle.net/11104/0295692 - 5.0455575 - MBÚ 2016 RIV GB eng J - Journal Article
Marhol, Petr - Bednář, P. - Kolářová, P. - Večeřa, R. - Ulrichová, J. - Tesařová, E. - Vavříková, Eva - Kuzma, Marek - Křen, Vladimír
Pharmacokinetics of pure silybin diastereoisomers and identification of their metabolites in rat plasma.
Journal of Functional Foods. Roč. 14, APR 2015 (2015), s. 570-580. ISSN 1756-4646. E-ISSN 2214-9414
R&D Projects: GA ČR(CZ) GAP301/11/0767; GA MŠMT LH13097
Institutional support: RVO:61388971
Keywords : Silybin * Silibinin * Silybin glucuronide
Subject RIV: CE - Biochemistry
Impact factor: 3.973, year: 2015
Permanent Link: http://hdl.handle.net/11104/0256209 - 6.0435567 - MBÚ 2015 RIV NL eng J - Journal Article
Charrier, C. - Azerad, R. - Marhol, Petr - Purchartová, K. - Kuzma, Marek - Křen, Vladimír
Preparation of silybin phase II metabolites: Streptomyces catalyzed glucuronidation.
Journal of Molecular Catalysis B-Enzymatic. Roč. 102, APR 2014 (2014), s. 167-173. ISSN 1381-1177
R&D Projects: GA MŠMT(CZ) LD13041; GA ČR(CZ) GAP301/11/0662
Institutional support: RVO:61388971
Keywords : Silybin diastereomers * Silibinin * Silymarin
Subject RIV: CE - Biochemistry
Impact factor: 2.128, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239466 - 7.0432999 - MBÚ 2015 RIV DE eng J - Journal Article
Novotná, Michaela - Gažák, Radek - Biedermann, David - Di Meo, F. - Marhol, Petr - Kuzma, Marek - Bednárová, Lucie - Fuksová, Kateřina - Trouillas, P. - Křen, Vladimír
cis-trans Isomerization of silybins A and B.
Beilstein Journal of Organic Chemistry. -, č. 10 (2014), s. 1047-1063. ISSN 1860-5397. E-ISSN 1860-5397
R&D Projects: GA ČR GAP207/10/0288; GA MŠMT LH13097; GA MŠMT(CZ) LD13041
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : isomerization * silibinin * silybin
Subject RIV: CC - Organic Chemistry
Impact factor: 2.757, year: 2014
Permanent Link: http://hdl.handle.net/11104/0237298 - 8.0428380 - MBÚ 2015 RIV CH eng J - Journal Article
Vavříková, Eva - Vacek, J. - Valentová, Kateřina - Marhol, Petr - Ulrichová, J. - Kuzma, Marek - Křen, Vladimír
Chemo-enzymatic synthesis of silybin and 2,3-dehydrosilybin dimers.
Molecules. Roč. 19, č. 4 (2014), s. 4115-4134. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) LD13041
Institutional support: RVO:61388971
Keywords : flavonolignan * silybin * silibinin
Subject RIV: CE - Biochemistry
Impact factor: 2.416, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233765 - 9.0428336 - MBÚ 2015 RIV NL eng J - Journal Article
Theodosiou, E. - Purchartová, Kateřina - Stamatis, H. - Kolisis, F. - Křen, Vladimír
Bioavailability of silymarin flavonolignans: drug formulations and biotransformation.
Phytochemistry Reviews. Roč. 13, č. 1 (2014), s. 1-18. ISSN 1568-7767. E-ISSN 1572-980X
R&D Projects: GA ČR(CZ) GAP301/11/0662; GA MŠMT(CZ) LD11051; GA MŠMT(CZ) ME10027
Institutional support: RVO:61388971
Keywords : Silymarin * Silybin * Silibinin
Subject RIV: CE - Biochemistry
Impact factor: 2.407, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233696 - 10.0395307 - MBÚ 2014 RIV NL eng J - Journal Article
Marhol, Petr - Hartog, F. A. - van der Horst, A. M. - Wever, R. - Purchartová, Kateřina - Fuksová, Kateřina - Kuzma, Marek - Cvačka, Josef - Křen, Vladimír
Preparation of silybin and isosilybin sulfates by sulfotransferase from Desulfitobacterium hafniense.
Journal of Molecular Catalysis B-Enzymatic. Roč. 89, MAY (2013), s. 24-27. ISSN 1381-1177
R&D Projects: GA ČR(CZ) GAP301/11/0662; GA MŠMT(CZ) LD11051; GA MŠMT(CZ) ME10027
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : Silybin * Silibinin * Isosilybin
Subject RIV: CE - Biochemistry
Impact factor: 2.745, year: 2013
Permanent Link: http://hdl.handle.net/11104/0223378