Search results
- 1.0554292 - ÚMG 2022 RIV DE eng J - Journal Article
Adamowicz, M. - Hailstone, R. - Demin, A.A. - Komulainen, E. - Hanzlíková, Hana - Brazina, J. - Gautam, A. - Wells, S. - Caldecott, Keith
XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair.
Nature Cell Biology. Roč. 23, č. 12 (2021), s. 1287-1298. ISSN 1465-7392. E-ISSN 1476-4679
Institutional support: RVO:68378050
Keywords : rna-polymerase-ii * single-strand breaks * histone h2b ubiquitylation * poly(adp-ribose) polymerase * adp-ribosylation * dependent monoubiquitylation * chromatin-structure * cellular-response * terminal domain * human homolog
OECD category: Cell biology
Impact factor: 28.213, year: 2021
Method of publishing: Open access
https://www.nature.com/articles/s41556-021-00792-w
Permanent Link: http://hdl.handle.net/11104/0328927 - 2.0544973 - ÚMG 2022 RIV US eng J - Journal Article
Komulainen, E. - Badman, J. - Rey, S. - Rulten, S. - Ju, L. - Fennell, K. - Kalasová, Ilona - Ilievová, Kristýna - McKinnon, P.J. - Hanzlíková, Hana - Staras, K. - Caldecott, Keith
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures.
Embo Reports. Roč. 22, č. 5 (2021), č. článku e51851. ISSN 1469-221X. E-ISSN 1469-3178
Institutional support: RVO:68378050
Keywords : DNA strand break * neurodegeneration * poly(ADP‐ * ribose) polymerase * seizures * xrcc1
OECD category: Biochemistry and molecular biology
Impact factor: 9.421, year: 2021
Method of publishing: Open access
https://www.embopress.org/doi/full/10.15252/embr.202051851
Permanent Link: http://hdl.handle.net/11104/0321763 - 3.0544972 - ÚMG 2022 RIV US eng J - Journal Article
Demin, A.A. - Hirota, K. - Tsuda, M. - Adamowicz, M. - Hailstone, R. - Brazina, J. - Gittens, W. - Kalasová, Ilona - Shao, Z. - Zha, S. - Sasanuma, H. - Hanzlíková, Hana - Takeda, S. - Caldecott, Keith
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
Molecular Cell. Roč. 81, č. 14 (2021), s. 3018-3030. ISSN 1097-2765. E-ISSN 1097-4164
Institutional support: RVO:68378050
Keywords : strand-break repair * polymerase-beta * poly(adp-ribose) polymerase * polynucleotide kinase * ligase iii * molecular-cloning * adp-ribosylation * protein xrcc1 * brct domain * damage
OECD category: Biochemistry and molecular biology
Impact factor: 19.328, year: 2021
Method of publishing: Open access
https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00366-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS109727652100366X%3Fshowall%3Dtrue
Permanent Link: http://hdl.handle.net/11104/0321762 - 4.0531327 - ÚMG 2021 RIV GB eng J - Journal Article
Hanzlíková, Hana - Prokhorova, E. - Krejčíková, Kateřina - Cihlářová, Zuzana - Kalasová, Ilona - Kubovčiak, Jan - Šáchová, Jana - Hailstone, R. - Brazina, J. - Ghosh, S. - Cirak, S. - Gleeson, J. G. - Ahel, I. - Caldecott, Keith
Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair.
Nature Communications. Roč. 11, č. 1 (2020), č. článku 3391. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) LM2015062; GA MŠMT(CZ) EF16_013/0001775; GA MŠMT LO1419; GA TA ČR TE02000058
Institutional support: RVO:68378050
Keywords : poly(adp-ribose) glycohydrolase * xrcc1 * binding * identification * ribosylation * degradation * specificity * serine * ataxia * roles
OECD category: Cell biology
Impact factor: 14.919, year: 2020
Method of publishing: Open access
https://www.nature.com/articles/s41467-020-17069-9
Permanent Link: http://hdl.handle.net/11104/0310004 - 5.0508183 - ÚMG 2020 RIV GB eng J - Journal Article
Hanzlíková, Hana - Caldecott, Keith
Perspectives on PARPs in S Phase.
Trends in Genetics. Roč. 35, č. 6 (2019), s. 412-422. ISSN 0168-9525. E-ISSN 1362-4555
Institutional support: RVO:68378050
Keywords : double-strand breaks * replication fork progression * dna-polymerase-alpha * homologous-recombination * poly(adp-ribose) polymerase * adp-ribosylation * damage response * stalled forks * repair * topoisomerase
OECD category: Cell biology
Impact factor: 11.333, year: 2019
Method of publishing: Limited access
https://www.cell.com/trends/genetics/fulltext/S0168-9525(19)30054-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS016895251930054X%3Fshowall%3Dtrue
Permanent Link: http://hdl.handle.net/11104/0305944File Download Size Commentary Version Access Trends_in_Genetics_H_Hanzlikova_2019.pdf 4 957.8 KB Author’s postprint require - 6.0495899 - ÚMG 2019 RIV US eng J - Journal Article
Hanzlíková, Hana - Kalasová, Ilona - Demin, A.A. - Pennicott, L.E. - Cihlářová, Zuzana - Caldecott, Keith
The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication.
Molecular Cell. Roč. 71, č. 2 (2018), s. 319-331. ISSN 1097-2765. E-ISSN 1097-4164
R&D Projects: GA MŠMT(CZ) LM2015062; GA MŠMT LO1419
Institutional support: RVO:68378050
Keywords : base-excision-repair * double-strand breaks * hydroxyurea-induced accumulation * immunodeficient patient 46br * poly-adp-ribose * mouse l-cells * ligase-iii * damaged dna * sv40 dna * in-vitro
OECD category: Biochemistry and molecular biology
Impact factor: 14.548, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288783File Download Size Commentary Version Access Molecular_Cell_H_Hanzlikova_2018.pdf 3 4.8 MB Author’s postprint require - 7.0437659 - ÚOCHB 2015 CZ eng A - Abstract
Downey, Alan Michael - Hocek, Michal
Protecting group-free strategies for the synthesis of nucleosides.
Liblice 2014. 49th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2014. s. 56.
[Liblice 2014. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /49./. 07.11.2014-09.11.2014, Lázně Bělohrad]
R&D Projects: GA ČR GAP207/11/0344
Institutional support: RVO:61388963
Keywords : nucleosides * per-O-acetylated ribose
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0241392 - 8.0369504 - BTÚ 2012 RIV GB eng J - Journal Article
Tomasetti, M. - Amati, M. - Nocchi, L. - Saccucci, F. - Strafella, E. - Tarquini, L.M. - Carbonari, D. - Alleva, R. - Borghi, B. - Neužil, Jiří - Bracci, M. - Santarelli, L.
Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis.
MUTAGENESIS. Roč. 26, č. 5 (2011), s. 585-591. ISSN 0267-8357
Institutional research plan: CEZ:AV0Z50520701
Keywords : Asbestos exposure * poly(ADP-ribose) polymerase-1 * malignant mesothelioma
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0203552 - 9.0361637 - BTÚ 2012 RIV US eng J - Journal Article
Nocchi, L. - Tomasetti, M. - Amati, M. - Neužil, Jiří - Santarelli, L. - Saccucci, F.
Thrombomodulin Is Silenced in Malignant Mesothelioma by a Poly(ADP-ribose) Polymerase-1-mediated Epigenetic Mechanism.
Journal of Biological Chemistry. Roč. 286, č. 22 (2011), s. 19478-19488. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA204/08/0811
Institutional research plan: CEZ:AV0Z50520701
Keywords : Thrombomodulin gene promoter * malignant mesothelioma * poly(ADP-ribose) polymerase-1
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.773, year: 2011
Permanent Link: http://hdl.handle.net/11104/0198906 - 10.0324598 - BFÚ 2009 RIV US eng J - Journal Article
Šponer, Jiří - Zgarbová, M. - Jurečka, Petr - Riley, K.E. - Šponer, Judit E. - Hobza, Pavel
Reference quantum chemical calculations on RNA base pairs directly involving the 2'-OH group of ribose.
[Referenční kvantově chemické výpočty párů bází RNA přímo využívajících 2'-OH skupinu ribózy.]
Journal of Chemical Theory and Computation. Roč. 5, č. 4 (2009), s. 1166-1179. ISSN 1549-9618. E-ISSN 1549-9626
R&D Projects: GA AV ČR(CZ) IAA400040802; GA AV ČR(CZ) IAA400550701; GA MŠMT(CZ) LC06030; GA MŠMT(CZ) LC512
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z40550506
Keywords : RNA * ribose * quantum calculations
Subject RIV: BO - Biophysics
Impact factor: 4.804, year: 2009
Permanent Link: http://hdl.handle.net/11104/0172250