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- 1.0579447 - ÚOCHB 2025 RIV GB eng J - Journal Article
Misehe, Mbilo - Šála, Michal - Matoušová, Marika - Hercík, Kamil - Kocek, Hugo - Chalupská, Dominika - Chaloupecká, Ema - Hájek, Miroslav - Bouřa, Evžen - Mertlíková-Kaiserová, Helena - Nencka, Radim
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors.
Bioorganic & Medicinal Chemistry. Roč. 97, January (2024), č. článku 129567. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : kinase inhibitor * thieno [2,3d] pyrimidine derivative * receptor-interacting protein kinase 2 * RIPK2 * NOD
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.bmcl.2023.129567
Permanent Link: https://hdl.handle.net/11104/0348249File Download Size Commentary Version Access 10.1016j.bmcl.2023.129567.pdf 0 1.6 MB Publisher’s postprint open-access - 2.0491055 - BFÚ 2019 RIV IE eng J - Journal Article
Procházková, J. - Střapacova, S. - Svrzkova, L. - Andrysík, Z. - Hýžd'alová, M. - Hrubá, E. - Pěnčíková, K. - Líbalová, Helena - Topinka, Jan - Kléma, J. - Espinosa, J. M. - Vondráček, Jan - Machala, M.
Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.
Toxicology Letters. Roč. 292, AUG 2018 (2018), s. 162-174. ISSN 0378-4274. E-ISSN 1879-3169
Institutional support: RVO:68081707 ; RVO:68378041
Keywords : aryl-hydrocarbon-receptor * polycyclic aromatic-hydrocarbons * interacting protein kinase-2 * cancer-cells * branching morphogenesis
OECD category: Genetics and heredity (medical genetics to be 3); Genetics and heredity (medical genetics to be 3) (UEM-P)
Impact factor: 3.499, year: 2018
Permanent Link: http://hdl.handle.net/11104/0285143 - 3.0467239 - ÚEB 2017 RIV US eng J - Journal Article
Bazgier, Václav - Berka, K. - Otyepka, M. - Banáš, P.
Exponential Repulsion Improves Structural Predictability of Molecular Docking.
Journal of Computational Chemistry. Roč. 37, č. 28 (2016), s. 2485-2494. ISSN 0192-8651. E-ISSN 1096-987X
Institutional support: RVO:61389030
Keywords : cyclin-dependent kinases * structure-based design * scoring functions * cdk2 inhibitors * force-field * ligand interactions * drug discovery * purine * potent * protein-kinase-2 * molecular docking * dock 6.6 * drug design * cyclin-dependent kinase 2 * directory of decoys
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 3.229, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265352File Download Size Commentary Version Access 2016_Bazgier_JOURNAL OF COMPUTATIONAL CHEMISTRY_2485.pdf 0 445.8 KB Other open-access