Search results
- 1.0576534 - ÚOCHB 2024 RIV US eng J - Journal Article
Kouba, P. - Kohout, P. - Haddadi, F. - Bushuiev, A. - Samusevich, Raman - Sedlář, J. - Damborský, J. - Pluskal, Tomáš - Sivič, J. - Mazurenko, S.
Machine Learning-Guided Protein Engineering.
ACS Catalysis. Roč. 13, č. 21 (2023), s. 13863-13895. ISSN 2155-5435. E-ISSN 2155-5435
R&D Projects: GA ČR(CZ) GM21-11563M; GA MŠMT(CZ) LM2023055; GA MŠMT LX22NPO5102
EU Projects: European Commission(XE) 891397 - KavaTarget
Research Infrastructure: RECETOX RI II - 90269
Institutional support: RVO:61388963
Keywords : activity * artificial intelligence * biocatalysis * deep learning * protein design
OECD category: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Impact factor: 12.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acscatal.3c02743
Permanent Link: https://hdl.handle.net/11104/0346095File Download Size Commentary Version Access 10.1021acscatal.3c02743.pdf 1 3.1 MB Publisher’s postprint open-access - 2.0539596 - ÚMG 2021 RIV SE eng J - Journal Article
Marek, M. - Chaloupková, R. - Prudnikova, T. - Sato, Y. - Řezáčová, Pavlína - Nagata, Y. - Smatanová, I.K. - Damborský, J.
Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family.
Computational and Structural Biotechnology Journal. Roč. 18, June (2020), s. 1352-1362. ISSN 2001-0370. E-ISSN 2001-0370
Institutional support: RVO:68378050
Keywords : Haloalkane dehalogenase (HLD) * Biocatalysis * Loop-helix transplantation * X-ray crystallography * Enantioselectivity * Access tunnel * Enzyme engineering * Protein design
OECD category: Biochemistry and molecular biology
Impact factor: 7.271, year: 2020
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2001037020302828?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0317304 - 3.0498264 - ÚOCHB 2019 RIV US eng J - Journal Article
Chrudinová, Martina - Žáková, Lenka - Marek, Aleš - Socha, Ondřej - Buděšínský, Miloš - Hubálek, Martin - Pícha, Jan - Macháčková, Kateřina - Jiráček, Jiří - Selicharová, Irena
A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding.
Journal of Biological Chemistry. Roč. 293, č. 43 (2018), s. 16818-16829. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : insulin * insulin-like growth factor (IGF) * structure-function * insulin receptor * protein design * kinetics * binding * Site 1
OECD category: Biochemistry and molecular biology
Impact factor: 4.106, year: 2018
http://www.jbc.org/content/293/43/16818.full
Permanent Link: http://hdl.handle.net/11104/0291126File Download Size Commentary Version Access 0498264.pdf 2 2.3 MB Publisher’s postprint open-access - 4.0472381 - ÚOCHB 2017 RIV US eng J - Journal Article
Březovský, J. - Babková, P. - Degtjarik, O. - Fořtová, A. - Gora, A. - Iermak, I. - Řezáčová, Pavlína - Dvořák, P. - Kutá Smatanová, I. - Prokop, Z. - Chaloupková, R. - Damborský, J.
Engineering a de Novo Transport Tunnel.
ACS Catalysis. Roč. 6, č. 11 (2016), s. 7597-7610. ISSN 2155-5435. E-ISSN 2155-5435
Institutional support: RVO:61388963
Keywords : transport tunnel * protein engineering * protein design * activity * specificity
Subject RIV: CE - Biochemistry
Impact factor: 10.614, year: 2016
Permanent Link: http://hdl.handle.net/11104/0269704 - 5.0472361 - MBÚ 2017 RIV US eng J - Journal Article
Březovský, J. - Babková, P. - Degtjarik, Oksana - Fořtová, A. - Gora, A. - Iermak, Iuliia - Řezáčová, Pavlína - Dvořák, P. - Kutá Smatanová, Ivana - Prokop, Z. - Chaloupková, R. - Damborský, J.
Engineering a de Novo Transport Tunnel.
ACS Catalysis. Roč. 6, č. 11 (2016), s. 7597-7610. ISSN 2155-5435. E-ISSN 2155-5435
Institutional support: RVO:61388971 ; RVO:68378050
Keywords : transport tunnel * protein engineering * protein design
Subject RIV: EE - Microbiology, Virology
Impact factor: 10.614, year: 2016
Permanent Link: http://hdl.handle.net/11104/0269689 - 6.0467009 - ÚOCHB 2017 RIV US eng J - Journal Article
Palani, Kirubakaran - Pfeiferová, Lucie - Boušová, Kristýna - Bednárová, Lucie - Obšilová, V. - Vondrášek, Jiří
Artificial proteins as allosteric modulators of PDZ3 and SH3 in two-domain constructs: A computational characterization of novel chimeric proteins.
Proteins-Structure, Function and Bioinformatics. Roč. 84, č. 10 (2016), s. 1358-1374. ISSN 0887-3585. E-ISSN 1097-0134
Institutional support: RVO:61388963
Keywords : protein design * fusion proteins * PDZ3 * SH3 * Trp-cage * two domain proteins
Subject RIV: CE - Biochemistry
Impact factor: 2.289, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265168 - 7.0463459 - FGÚ 2017 RIV US eng J - Journal Article
Palani, K. - Pfeiferová, L. - Boušová, Kristýna - Bednárová, L. - Obšilová, Veronika - Vondrášek, J.
Artificial proteins as allosteric modulators of PDZ3 and SH3 in two-domain constructs: A computational characterization of novel chimeric proteins.
Proteins-Structure, Function and Bioinformatics. Roč. 84, č. 10 (2016), s. 1358-1374. ISSN 0887-3585. E-ISSN 1097-0134
Institutional support: RVO:67985823
Keywords : protein design * fusion proteins * PDZ3 * SH3 * Trp-cage * two domain proteins * molecular dynamics simulation * circular dichroism
Subject RIV: BO - Biophysics
Impact factor: 2.289, year: 2016
Permanent Link: http://hdl.handle.net/11104/0262657 - 8.0459903 - ÚOCHB 2017 CZ eng A - Abstract
Bouřa, Evžen
Protein design for macromolecular crystallography.
Prague Protein Spring Meeting 2016: Proteins and their Design. Praha: Ústav organické chemie a biochemie AV ČR, 2016. s. 26. ISBN 978-80-86241-55-5.
[Prague Protein Spring Meeting 2016: Proteins and their Design /4./. 05.05.2016-08.05.2016, Praha]
Institutional support: RVO:61388963
Keywords : protein design * macromolecular crystallography
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0260058 - 9.0458657 - ÚOCHB 2017 RIV GB eng J - Journal Article
Viková, Jitka - Collinsová, Michaela - Kletvíková, Emília - Buděšínský, Miloš - Kaplan, V. - Žáková, Lenka - Veverka, Václav - Hexnerová, Rozálie - Tarazona Avinó, R. J. - Straková, Jana - Selicharová, Irena - Vaněk, Václav - Wright, D. W. - Watson, C. J. - Turkenburg, J. P. - Brzozowski, A. M. - Jiráček, Jiří
Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Scientific Reports. Roč. 6, Jan 21 (2016), č. článku 19431. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LK11205; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : insulin * insulin receptor * diabetes * protein design * protein synthesis
Subject RIV: CE - Biochemistry
Impact factor: 4.259, year: 2016
http://www.nature.com/articles/srep19431
Permanent Link: http://hdl.handle.net/11104/0258905File Download Size Commentary Version Access 0458657.pdf 5 2.4 MB Publisher’s postprint open-access