Search results
- 1.0542896 - MBÚ 2022 RIV NL eng J - Journal Article
Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Dvořáková, Barbora - Šírová, Milada - Říhová, Blanka - Randárová, Eva - Kraus, Michal - Tomala, Jakub - Studenovský, Martin - Vondráčková, Michaela - Sedláček, Radislav - Makovický, Peter - Fučíková, J. - Vošahlíková, Š. - Spíšek, R. - Kostka, Libor - Etrych, Tomáš - Kovář, Marek
Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
Journal of Controlled Release. Roč. 332, APR 10 2021 (2021), s. 563-580. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) ED1.1.00/02.0109
Research Infrastructure: CCP - 90040
Institutional support: RVO:61388971 ; RVO:61389013 ; RVO:68378050
Keywords : Ritonavir derivate * Polymer carrier * pH-controlled release * Antitumor activity * Proteasome inhibition * STAT3 signaling inhibition
OECD category: Microbiology; Polymer science (UMCH-V)
Impact factor: 11.467, year: 2021 ; AIS: 1.655, rok: 2021
Method of publishing: Limited access
Result website:
https://www.sciencedirect.com/science/article/pii/S0168365921001267DOI: https://doi.org/10.1016/j.jconrel.2021.03.015
Permanent Link: http://hdl.handle.net/11104/0320232File Download Size Commentary Version Access Polymer-ritonavir derivate nanomedicine.pdf 1 11.3 MB Publisher’s postprint require - 2.0492820 - ÚMCH 2019 RIV US eng J - Journal Article
Chytil, Petr - Šírová, Milada - Kudláčová, Júlia - Říhová, Blanka - Ulbrich, Karel - Etrych, Tomáš
Bloodstream stability predetermines the antitumor efficacy of micellar polymer-doxorubicin drug conjugates with pH-triggered drug release.
Molecular Pharmaceutics. Roč. 15, č. 9 (2018), s. 3654-3663. ISSN 1543-8384. E-ISSN 1543-8392
R&D Projects: GA ČR(CZ) GA17-08084S; GA ČR(CZ) GA17-13283S; GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : degradation * HPMA copolymer * pH-controlled release
OECD category: Polymer science; Microbiology (MBU-M)
Impact factor: 4.396, year: 2018 ; AIS: 0.992, rok: 2018
DOI: https://doi.org/10.1021/acs.molpharmaceut.8b00156
Permanent Link: http://hdl.handle.net/11104/0286873 - 3.0490217 - ÚMCH 2019 ES eng A - Abstract
Kousalová, Jana - Studenovský, Martin - Sivák, Ladislav - Kovář, Marek - Etrych, Tomáš
Targeted inhibition of the metastatic process by biodegradable conjugates with MMP inhibitors.
Final Program. Valencia: Centro de Investigación Príncipe Felipe, 2018. s. 104.
[International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice /12./. 28.05.2018-30.05.2018, Valencia]
R&D Projects: GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : inhibitor matrix matelloproteinase * drug delivery systems * pH-controlled release
OECD category: Polymer science; Microbiology (MBU-M)
Permanent Link: http://hdl.handle.net/11104/0284684 - 4.0490215 - ÚMCH 2019 ES eng A - Abstract
Chytil, Petr - Nakamura, H. - Koziolová, Eva - Maeda, H. - Etrych, Tomáš
Tumor-targeted linear HPMA polymer conjugates with pirarubicin - influence of polymer dispersity on biodistribution and anticancer activity.
Final Program. Valencia: Centro de Investigación Príncipe Felipe, 2018. s. 70.
[International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice /12./. 28.05.2018-30.05.2018, Valencia]
R&D Projects: GA ČR(CZ) GA17-08084S
Institutional support: RVO:61389013
Keywords : drug delivery systems * pH-controlled release * HPMA copolymers
OECD category: Polymer science
Permanent Link: http://hdl.handle.net/11104/0284683 - 5.0480676 - ÚMCH 2018 CN eng A - Abstract
Chytil, Petr - Šírová, Milada - Laga, Richard - Braunová, Alena - Etrych, Tomáš
Tumor-targeted HPMA-based polymer micelles enabling pH-triggered drug release.
Conference Abstract Book. Dalian: BIT Group Global Ltd., 2017. s. 421.
[BIT´s Annual World Congress of Nano Science and Technology-2017 /7./ - Nano S&T-2017. 24.10.2017-26.10.2017, Fukuoka]
R&D Projects: GA MŠMT(CZ) LO1507; GA ČR(CZ) GA17-08084S
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : drug delivery systems * pH-controlled release * HPMA copolymers
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0276506 - 6.0476593 - ÚMCH 2018 RIV GB eng J - Journal Article
Chen, Y. - Tezcan, O. - Li, D. - Beztsinna, N. - Lou, B. - Etrych, Tomáš - Ulbrich, Karel - Metselaar, J. M. - Lammers, T. - Hennink, W. E.
Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin.
Nanoscale. Roč. 9, č. 29 (2017), s. 10404-10419. ISSN 2040-3364. E-ISSN 2040-3372
R&D Projects: GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013
Keywords : drug delivery * doxorubicin * pH controlled release
OECD category: Polymer science
Impact factor: 7.233, year: 2017 ; AIS: 1.704, rok: 2017
DOI: https://doi.org/10.1039/C7NR03592F
Permanent Link: http://hdl.handle.net/11104/0273255 - 7.0466968 - ÚMCH 2017 HU eng A - Abstract
Chytil, Petr - Etrych, Tomáš
Tumor-targeted polymer drug carriers for controlled delivery and drug release.
Brochure of ABIOG Partners - 3rd Meeting of ABIOG project managements committee & Workshop. Budapest: Department of Physical Chemistry and Materials Science, Budapest University of Technology and Economics, 2016. s. 15.
[Meeting of ABIOG Project Managements Committee /3./ & Workshop. 08.12.2016-09.12.2016, Budapest]
Grant - others:International Visegrad Fund under Small Grant Programme(XE) 21620101
Institutional support: RVO:61389013
Keywords : drug delivery systems * pH-controlled release * HPMA copolymers
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0265203 - 8.0462377 - ÚMCH 2017 SK eng A - Abstract
Chytil, Petr - Koziolová, Eva - Starovoytova, Larisa - Nakamura, H. - Maeda, H. - Etrych, Tomáš
Tumor-targeted HPMA copolymer - pirarubicin conjugates - advanced synthesis by RAFT polymerization.
22nd Bratislava International Conference on Macromolecules - BIMac 2016, programme book and book of abstracts. Bratislava: Polymer Institute of the Slovak Academy of Sciences, 2016 - (Podhradská, S.; Mosnáček, J.). s. 62. ISBN 978-80-89841-01-1.
[Bratislava International Conference on Macromolecules /22./ - BIMac 2016. 06.09.2016-09.09.2016, Bratislava]
R&D Projects: GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013
Keywords : drug delivery systems * pH-controlled release * HPMA copolymers
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0262147 - 9.0460191 - ÚMCH 2017 SK cze A - Abstract
Chytil, Petr - Lomkova, Ekaterina A. - Janoušková, Olga - Filippov, Sergey K. - Ulbrich, Karel - Etrych, Tomáš
Micelární polymerní konjugáty betulinové kyseliny určené pro cílenou léčbu nádorových onemocnění.
Program a Zborník príspevkov. Bratislava: Ústav polymérov SAV, 2016. s. 24-25. ISBN 978-80-89841-00-4.
[Slovensko-Česká konferencia Polyméry 2016 /9./. 08.06.2016-10.06.2016, Stará Lesná]
R&D Projects: GA ČR(CZ) GA15-02986S; GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013
Keywords : drug delivery systems * pH-controlled release * HPMA copolymers
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0260327 - 10.0458848 - ÚMCH 2017 NL eng A - Abstract
Lomkova, Ekaterina A. - Chytil, Petr - Janoušková, Olga - Filippov, Sergey K. - Ulbrich, Karel - Etrych, Tomáš
Biodegradable micellar HPMA-based polymer-drug conjugates with betulinic acid.
Abstract Book. Enschede: University of Twente, 2016 - (Paulusse, J.). s. 96-97. ISBN 978-90-365-4075-9.
[European Symposium on Controlled Drug Delivery /14./. 13.04.2016-15.04.2016, Egmond aan Zee]
R&D Projects: GA ČR(CZ) GA15-02986S; GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013
Keywords : drug delivery systems * pH-controlled release * HPMA copolymers
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0259114