Search results
- 1.0566162 - FGÚ 2023 RIV GB eng J - Journal Article
Jakubík, Jan - Randáková, Alena
Insights into the operational model of agonism of receptor dimers.
Expert Opinion on Drug Discovery. Roč. 17, č. 11 (2022), s. 1181-1191. ISSN 1746-0441. E-ISSN 1746-045X
R&D Projects: GA ČR(CZ) GJ19-06106Y
Institutional support: RVO:67985823
Keywords : operational model of agonism * operational efficacy * allosteric modulation * receptor dimers * GPCRs * receptor channels
OECD category: Pharmacology and pharmacy
Impact factor: 6.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1080/17460441.2023.2147502
Permanent Link: https://hdl.handle.net/11104/0337590 - 2.0504453 - FGÚ 2020 RIV GB eng J - Journal Article
Jakubík, Jan - Randáková, Alena - Rudajev, Vladimír - Zimčík, Pavel - El-Fakahany, E. E. - Doležal, Vladimír
Applications and limitations of fitting of the operational model to determine relative efficacies of agonists.
Scientific Reports. Roč. 9, Mar 15 (2019), č. článku 4637. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA17-16182S
Institutional support: RVO:67985823
Keywords : operational model of agonism * affinity * efficacy
OECD category: Physiology (including cytology)
Impact factor: 3.998, year: 2019
Method of publishing: Open access
https://doi.org/10.1038/s41598-019-40993-w
Permanent Link: http://hdl.handle.net/11104/0296081