Search results

  1. 1.
    0555574 - ÚOCHB 2023 RIV CZ cze J - Journal Article
    Krečmerová, Marcela
    Od 5-azapyrimidinové chemie k thiadiazolům.
    [From 5-Azapyrimidine Chemistry to Thiadiazoles.]
    Chemické listy. Roč. 116, č. 3 (2022), s. 152-162. ISSN 0009-2770. E-ISSN 1213-7103
    R&D Projects: GA MŠk(CZ) LM2018133
    Institutional support: RVO:61388963
    Keywords : 5-azacytidine * acyclic nucleoside phosphonate * thiadiazoles
    OECD category: Organic chemistry
    Impact factor: 0.381, year: 2020
    Method of publishing: Open access
    https://doi.org/10.54779/chl20220152
    Permanent Link: http://hdl.handle.net/11104/0330035
     
     
  2. 2.
    0543389 - ÚOCHB 2022 RIV GB eng J - Journal Article
    Lášek, Tomáš - Dobiaš, Juraj - Buděšínský, Miloš - Kozák, Jaroslav - Lapuníková, Barbora - Rosenberg, Ivan - Birkuš, Gabriel - Páv, Ondřej
    Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose D-nucleosides and tetradialdose D-nucleosides.
    Tetrahedron. Roč. 89, Jun 4 (2021), č. článku 132159. ISSN 0040-4020. E-ISSN 1464-5416
    R&D Projects: GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : nucleoside phosphonate * triphosphate * prodrug * tetradialdose d-nucleoside * 2′-fluoronucleoside
    OECD category: Organic chemistry
    Impact factor: 2.457, year: 2020
    Method of publishing: Limited access
    https://doi.org/10.1016/j.tet.2021.132159
    Permanent Link: http://hdl.handle.net/11104/0320603
     
     
  3. 3.
    0469886 - ÚOCHB 2017 RIV DE eng J - Journal Article
    Pomeisl, Karel - Beier, Petr - Pohl, Radek - Krečmerová, Marcela
    Novel and Efficient Synthesis of gem-Difluorinated Derivatives of Acyclic Nucleoside Phosphonates (ANPs).
    ChemistrySelect. Roč. 1, č. 10 (2016), s. 2102-2106. ISSN 2365-6549. E-ISSN 2365-6549
    R&D Projects: GA ČR(CZ) GA14-00522S
    Institutional support: RVO:61388963
    Keywords : difluoromethylation * difluoromethylphosphonate * acyclic nucleoside phosphonate * phosphonate ester * microwave reaction
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0267657
     
     
  4. 4.
    0455024 - ÚOCHB 2016 IL eng A - Abstract
    Krečmerová, Marcela
    Trends and challenges in chemistry of acyclic nucleoside phosphonates.
    6th International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC'15) and 13th Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society. Rehovot: European Federation for Medicinal Chemistry, 2015. s. 164.
    [International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC'15) /6./ and Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society /13./. 15.11.2015-18.11.2015, Rehovot]
    R&D Projects: GA MPO(CZ) FR-TI4/625
    Institutional support: RVO:61388963
    Keywords : 5-azacytosine * PME-azaC * acyclic nucleoside phosphonate * antivirals * prodrug
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0255679
     
     
  5. 5.
    0443963 - ÚOCHB 2016 RIV CZ eng J - Journal Article
    Potměšil, P. - Holý, Antonín - Zídek, Zdeněk
    Influence of Acyclic Nucleoside Phosphonate Antivirals on Gene Expression of Chemokine Receptors CCR5 and CXCR4.
    Folia Biologica. Roč. 61, č. 1 (2015), s. 1-7. ISSN 0015-5500. E-ISSN 0015-5500
    R&D Projects: GA ČR GA305/03/1470; GA MŠk 1M0508
    Institutional support: RVO:61388963 ; RVO:68378041
    Keywords : acyclic nucleoside phosphonate * HIV * CCR5 * CXCR4 * cytokine * RT-PCR
    Subject RIV: CC - Organic Chemistry; FR - Pharmacology ; Medidal Chemistry (UEM-P)
    Impact factor: 0.833, year: 2015
    Permanent Link: http://hdl.handle.net/11104/0246598
     
     
  6. 6.
    0429009 - ÚOCHB 2015 CZ eng C - Conference Paper (international conference)
    Kaiser, Martin Maxmilian - Novák, Pavel - Rosenbergová, Šárka - Poštová Slavětínská, Lenka - Rosenberg, Ivan - Janeba, Zlatko
    Oligonucleotides modified with acyclic nucleoside phosphonate (HPEP) units.
    Chemistry of Nucleic Acid Components. 16th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2014 - (Hocek, M.), s. 293-294. Collection Symposium Series, 14. ISBN 978-80-86241-50-0.
    [Symposium on Chemistry of Nucleic Acid Components /16./. Český Krumlov (CZ), 08.06.2014-13.06.2014]
    R&D Projects: GA TA ČR TA03010598
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonate * HPEP * oligonucleotides
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0234287
     
     
  7. 7.
    0428748 - ÚOCHB 2015 US eng A - Abstract
    Krečmerová, Marcela - Chupíková, Alice - Otmar, Miroslav - Andrei, G. - Balzarini, J. - Snoeck, R.
    News in the development of 5-azacytosine-based antivirals.
    27th International Conference on Antiviral Research (ICAR). Raleigh: International Society for Antiviral Research (ISAR), 2014. s. 63.
    [International Conference on Antiviral Research /27./. 12.05.2014-16.05.2014, Raleigh]
    Grant - others: AV ČR(CZ) M200551201
    Institutional support: RVO:61388963
    Keywords : 5-azacytosine * acyclic nucleoside phosphonate * antivirals * prodrug
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0234072
     
     
  8. 8.
    0428744 - ÚOCHB 2015 RIV GB eng J - Journal Article
    Krečmerová, Marcela - Pohl, Radek - Masojídková, Milena - Balzarini, J. - Snoeck, R. - Andrei, G.
    N-4-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: Chemistry and antiviral activity.
    Bioorganic & Medicinal Chemistry. Roč. 22, č. 10 (2014), s. 2896-2906. ISSN 0968-0896. E-ISSN 1464-3391
    R&D Projects: GA MPO FR-TI4/625
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonate * antivirals * 5-azacytosine * prodrug
    Subject RIV: CC - Organic Chemistry
    Impact factor: 2.793, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0234048
     
     
  9. 9.
    0427788 - ÚOCHB 2015 RIV US eng J - Journal Article
    Diblíková, D. - Kopečná, M. - Školová, B. - Krečmerová, Marcela - Roh, J. - Hrabálek, A. - Vávrová, K.
    Transdermal Delivery and Cutaneous Targeting of Antivirals using a Penetration Enhancer and Lysolipid Prodrugs.
    Pharmaceutical Research. Roč. 31, č. 4 (2014), s. 1071-1081. ISSN 0724-8741. E-ISSN 1573-904X
    Grant - others: GA ČR(CZ) GAP207/11/0365
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonate antivirals * lysolipid prodrug * penetration enhancer * skin absorption * transdermal drug delivery
    Subject RIV: FR - Pharmacology ; Medidal Chemistry
    Impact factor: 3.420, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0233366
     
     
  10. 10.
    0399428 - ÚOCHB 2014 CZ cze A - Abstract
    Krečmerová, Marcela - Tichý, Tomáš - Pomeisl, Karel
    Nové formy proléčiv biologicky aktivních nukleotidových analogů.
    [New prodrug forms of biologically active nucleotide analogues.]
    Liblice 2013. 48th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2013. s. 33-33.
    [Liblice 2013. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /48./. 01.11.2013-03.11.2013, Špindlerův Mlýn]
    R&D Projects: GA MPO FR-TI4/625
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonate * antivirals * cytostatics * prodrug
    Subject RIV: CC - Organic Chemistry
    Permanent Link: http://hdl.handle.net/11104/0226713