Search results
- 1.0555574 - ÚOCHB 2023 RIV CZ cze J - Journal Article
Krečmerová, Marcela
Od 5-azapyrimidinové chemie k thiadiazolům.
[From 5-Azapyrimidine Chemistry to Thiadiazoles.]
Chemické listy. Roč. 116, č. 3 (2022), s. 152-162. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA MŠk(CZ) LM2018133
Institutional support: RVO:61388963
Keywords : 5-azacytidine * acyclic nucleoside phosphonate * thiadiazoles * antivirotika * thiadiazoly * katepsin K * kinasa glykogensyntasy 3β * cystein-dependentní enzymy
OECD category: Organic chemistry
Impact factor: 0.356, year: 2021
Method of publishing: Open access
https://doi.org/10.54779/chl20220152
Permanent Link: http://hdl.handle.net/11104/0330035
- 2.0543389 - ÚOCHB 2022 RIV GB eng J - Journal Article
Lášek, Tomáš - Dobiaš, Juraj - Buděšínský, Miloš - Kozák, Jaroslav - Lapuníková, Barbora - Rosenberg, Ivan - Birkuš, Gabriel - Páv, Ondřej
Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose D-nucleosides and tetradialdose D-nucleosides.
Tetrahedron. Roč. 89, Jun 4 (2021), č. článku 132159. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA MŠk(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : nucleoside phosphonate * triphosphate * prodrug * tetradialdose d-nucleoside * 2′-fluoronucleoside
OECD category: Organic chemistry
Impact factor: 2.388, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.tet.2021.132159
Permanent Link: http://hdl.handle.net/11104/0320603
- 3.0469886 - ÚOCHB 2017 RIV DE eng J - Journal Article
Pomeisl, Karel - Beier, Petr - Pohl, Radek - Krečmerová, Marcela
Novel and Efficient Synthesis of gem-Difluorinated Derivatives of Acyclic Nucleoside Phosphonates (ANPs).
ChemistrySelect. Roč. 1, č. 10 (2016), s. 2102-2106. ISSN 2365-6549. E-ISSN 2365-6549
R&D Projects: GA ČR(CZ) GA14-00522S
Institutional support: RVO:61388963
Keywords : difluoromethylation * difluoromethylphosphonate * acyclic nucleoside phosphonate * phosphonate ester * microwave reaction
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0267657
- 4.0455024 - ÚOCHB 2016 IL eng A - Abstract
Krečmerová, Marcela
Trends and challenges in chemistry of acyclic nucleoside phosphonates.
6th International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC'15) and 13th Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society. Rehovot: European Federation for Medicinal Chemistry, 2015. s. 164.
[International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC'15) /6./ and Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society /13./. 15.11.2015-18.11.2015, Rehovot]
R&D Projects: GA MPO(CZ) FR-TI4/625
Institutional support: RVO:61388963
Keywords : 5-azacytosine * PME-azaC * acyclic nucleoside phosphonate * antivirals * prodrug
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0255679
- 5.0443963 - ÚOCHB 2016 RIV CZ eng J - Journal Article
Potměšil, P. - Holý, Antonín - Zídek, Zdeněk
Influence of Acyclic Nucleoside Phosphonate Antivirals on Gene Expression of Chemokine Receptors CCR5 and CXCR4.
Folia Biologica. Roč. 61, č. 1 (2015), s. 1-7. ISSN 0015-5500. E-ISSN 0015-5500
R&D Projects: GA ČR GA305/03/1470; GA MŠk 1M0508
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : acyclic nucleoside phosphonate * HIV * CCR5 * CXCR4 * cytokine * RT-PCR
Subject RIV: CC - Organic Chemistry; FR - Pharmacology ; Medidal Chemistry (UEM-P)
Impact factor: 0.833, year: 2015
Permanent Link: http://hdl.handle.net/11104/0246598
- 6.0429009 - ÚOCHB 2015 CZ eng C - Conference Paper (international conference)
Kaiser, Martin Maxmilian - Novák, Pavel - Rosenbergová, Šárka - Poštová Slavětínská, Lenka - Rosenberg, Ivan - Janeba, Zlatko
Oligonucleotides modified with acyclic nucleoside phosphonate (HPEP) units.
Chemistry of Nucleic Acid Components. 16th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2014 - (Hocek, M.), s. 293-294. Collection Symposium Series, 14. ISBN 978-80-86241-50-0.
[Symposium on Chemistry of Nucleic Acid Components /16./. Český Krumlov (CZ), 08.06.2014-13.06.2014]
R&D Projects: GA TA ČR TA03010598
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonate * HPEP * oligonucleotides
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0234287
- 7.0428748 - ÚOCHB 2015 US eng A - Abstract
Krečmerová, Marcela - Chupíková, Alice - Otmar, Miroslav - Andrei, G. - Balzarini, J. - Snoeck, R.
News in the development of 5-azacytosine-based antivirals.
27th International Conference on Antiviral Research (ICAR). Raleigh: International Society for Antiviral Research (ISAR), 2014. s. 63.
[International Conference on Antiviral Research /27./. 12.05.2014-16.05.2014, Raleigh]
Grant - others: AV ČR(CZ) M200551201
Institutional support: RVO:61388963
Keywords : 5-azacytosine * acyclic nucleoside phosphonate * antivirals * prodrug
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0234072
- 8.0428744 - ÚOCHB 2015 RIV GB eng J - Journal Article
Krečmerová, Marcela - Pohl, Radek - Masojídková, Milena - Balzarini, J. - Snoeck, R. - Andrei, G.
N-4-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: Chemistry and antiviral activity.
Bioorganic & Medicinal Chemistry. Roč. 22, č. 10 (2014), s. 2896-2906. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MPO FR-TI4/625
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonate * antivirals * 5-azacytosine * prodrug
Subject RIV: CC - Organic Chemistry
Impact factor: 2.793, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234048
- 9.0427788 - ÚOCHB 2015 RIV US eng J - Journal Article
Diblíková, D. - Kopečná, M. - Školová, B. - Krečmerová, Marcela - Roh, J. - Hrabálek, A. - Vávrová, K.
Transdermal Delivery and Cutaneous Targeting of Antivirals using a Penetration Enhancer and Lysolipid Prodrugs.
Pharmaceutical Research. Roč. 31, č. 4 (2014), s. 1071-1081. ISSN 0724-8741. E-ISSN 1573-904X
Grant - others: GA ČR(CZ) GAP207/11/0365
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonate antivirals * lysolipid prodrug * penetration enhancer * skin absorption * transdermal drug delivery
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 3.420, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233366
- 10.0399428 - ÚOCHB 2014 CZ cze A - Abstract
Krečmerová, Marcela - Tichý, Tomáš - Pomeisl, Karel
Nové formy proléčiv biologicky aktivních nukleotidových analogů.
[New prodrug forms of biologically active nucleotide analogues.]
Liblice 2013. 48th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2013. s. 33-33.
[Liblice 2013. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /48./. 01.11.2013-03.11.2013, Špindlerův Mlýn]
R&D Projects: GA MPO FR-TI4/625
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonate * antivirals * cytostatics * prodrug
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0226713