Search results
- 1.0580493 - BC 2024 RIV CH eng J - Journal Article
Martins, Larissa Almeida - Buša, Michal - Chlastáková, A. - Kotál, Jan - Beránková, Z. - Stergiou, N. - Jmel, Mohamed Amine - Schmitt, E. - Chmelař, J. - Mareš, Michael - Kotsyfakis, Michalis
Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host.
Cellular and Molecular Life Sciences. Roč. 80, č. 11 (2023), č. článku 339. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA ČR(CZ) GA19-07247S; GA MŠMT(CZ) EF16_019/0000759; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LTAUSA19109
Institutional support: RVO:60077344 ; RVO:61388963
Keywords : ray crystal-structure * sialostatin-l * functional expression * cysteine cathepsins * mammalian legumain * ixodes-scapularis * inhibitors * stefin * generation * peptidase * Ixodes ricinus * Tick saliva * Cystatins * Protease inhibition * Protein structure * Host-parasite interactions
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 8, year: 2022
Method of publishing: Limited access
https://link.springer.com/article/10.1007/s00018-023-04993-4
Permanent Link: https://hdl.handle.net/11104/0349268 - 2.0537297 - BC 2021 RIV GB eng J - Journal Article
Corrigan, T.S. - Diaz, L.M.L. - Border, S.E. - Ratigan, S.C. - Kasper, K.Q. - Sojka, Daniel - Fajtova, P. - Caffrey, C.R. - Salvesen, G. S. - McElroy, C.A. - Hadad, C.M. - Ekici, O.D.
Design, synthesis, andin vitroevaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 35, č. 1 (2020), s. 1387-1402. ISSN 1475-6366. E-ISSN 1475-6374
R&D Projects: GA MŠMT(CZ) EF16_019/0000759
Institutional support: RVO:60077344
Keywords : asparaginyl endopeptidase * schistosoma-mansoni * michael acceptors * caspase family * key mediators * legumain * expression * potent * generation * epoxides * Proteasome inhibitor * caspase and legumain inhibitors * aza-peptide carbonyls * anticancer * antiparasitic
OECD category: Microbiology
Impact factor: 5.051, year: 2020
Method of publishing: Open access
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2020.1781107?needAcces
Permanent Link: http://hdl.handle.net/11104/0315029 - 3.0498704 - BC 2019 RIV AU eng J - Journal Article
Hartmann, David - Šíma, Radek - Konvičková, Jitka - Perner, Jan - Kopáček, Petr - Sojka, Daniel
Multiple legumain isoenzymes in ticks.
International Journal for Parasitology. Roč. 48, č. 2 (2018), s. 167-178. ISSN 0020-7519. E-ISSN 1879-0135
R&D Projects: GA ČR GA14-33693S; GA ČR GA13-11043S
Institutional support: RVO:60077344
Keywords : Asparaginyl endopeptidase * Hemoglobin * Legumain * Ticks * Vector
OECD category: Biochemical research methods
Impact factor: 3.478, year: 2018
Permanent Link: http://hdl.handle.net/11104/0290986 - 4.0335281 - BC 2010 RIV US eng J - Journal Article
Ovat, A. - Muindi, F. - Fagan, C. - Brouner, M. - Hansell, E. - Dvořák, J. - Sojka, Daniel - Kopáček, Petr - McKerrow, J. H. - Caffrey, C. R. - Powers, J. C.
Aza-Peptidyl Michael Acceptor and Epoxide Inhibitors—Potent and Selective Inhibitors of Schistosoma mansoni and Ixodes ricinus Legumains (Asparaginyl Endopeptidases).
Journal of Medicinal Chemistry. Roč. 52, č. 22 (2009), s. 7192-7210. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GA206/06/0865; GA MŠMT(CZ) LC06009
Institutional research plan: CEZ:AV0Z60220518
Keywords : legumain * IrAE * aza-peptide Michael acceptors
Subject RIV: EC - Immunology
Impact factor: 4.802, year: 2009
Permanent Link: http://hdl.handle.net/11104/0179788 - 5.0318080 - BC 2009 RIV US eng J - Journal Article
Götz, M. G. - James, K. E. - Hansell, E. - Dvořák, J. - Seshaadri, A. - Sojka, Daniel - Kopáček, Petr - McKerrow, J. H. - Caffrey, C. R. - Powers, J. C.
Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens.
[Aza-peptidy Michael Acceptors. Nová třída účinných a selektivních inhibitorů asparaginylových peptidáz (legumainů) z evolučně vzdálených patogenů.]
Journal of Medicinal Chemistry. Roč. 51, č. 9 (2008), s. 2816-2832. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LC06009; GA ČR GA206/06/0865
Grant - others:The National Institute of Allergy and Infectious Diseases(US) AI053247; National Institute of General Medical Sciences(US) GM54404; National Institute of General Medical Sciences(US) GM61964
Institutional research plan: CEZ:AV0Z60220518
Keywords : legumain * IrAE * aza-peptide Michael acceptors
Subject RIV: ED - Physiology
Impact factor: 4.898, year: 2008
Permanent Link: http://hdl.handle.net/11104/0167567