Search results
- 1.0563157 - ÚOCHB 2023 RIV US eng J - Journal Article
Vavřina, Zdeněk - Perlíková, Pavla - Milisavljevič, Nemanja - Chevrier, Florian - Smola, Miroslav - Smith, Joshua - Dejmek, Milan - Havlíček, Vojtěch - Buděšínský, Miloš - Liboska, Radek - Vaneková, Lenka - Brynda, Jiří - Bouřa, Evžen - Řezáčová, Pavlína - Hocek, Michal - Birkuš, Gabriel
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
Journal of Medicinal Chemistry. Roč. 65, č. 20 (2022), s. 14082-14103. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : GMP-AMP synthase * interferon genes * adapter protein
OECD category: Biochemistry and molecular biology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.2c01305
Permanent Link: https://hdl.handle.net/11104/0335201File Download Size Commentary Version Access 10.1021acs.jmedchem.2c01305.pdf 5 6.9 MB Publisher’s postprint open-access - 2.0556414 - BTÚ 2022 RIV US eng J - Journal Article
Aliakbar Tehrani, Zahra - Rulíšek, Lubomír - Černý, Jiří
Molecular dynamics simulations provide structural insight into binding of cyclic dinucleotides to human STING protein.
Journal of Biomolecular Structure & Dynamics. JUN 2021, JUN 2021 (2021), č. článku 2021-07-12. ISSN 0739-1102
R&D Projects: GA MŠMT(CZ) EF16_013/0001777; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2018131; GA MŠMT(CZ) EF16_013/0001776; GA ČR(CZ) GA20-08772S
Research Infrastructure: CESNET II - 90042
Institutional support: RVO:86652036 ; RVO:61388963
Keywords : NETWORK ANALYSIS * INTERFERON GENES * LIGAND * RECOGNITION
OECD category: Biochemistry and molecular biology
Impact factor: 5.235, year: 2021
Method of publishing: Limited access
https://www.tandfonline.com/doi/full/10.1080/07391102.2021.1942213
Permanent Link: http://hdl.handle.net/11104/0330635 - 3.0554896 - BTÚ 2022 RIV US eng J - Journal Article
Vavrina, Z. - Gutten, O. - Smola, M. - Zavrel, M. - Tehrani, Zahra Aliakbar - Charvat, V. - Kožíšek, M. - Bouřa, E. - Birkus, G. - Rulíšek, L.
Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory.
Biochemistry. Roč. 60, č. 8 (2021), s. 607-620. ISSN 0006-2960
Institutional support: RVO:86652036
Keywords : cyclic di-gmp * interferon genes * dna sensor * dinucleotide
OECD category: Biochemistry and molecular biology
Impact factor: 3.321, year: 2021
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.biochem.0c00949
Permanent Link: http://hdl.handle.net/11104/0329535 - 4.0543611 - ÚOCHB 2022 RIV US eng J - Journal Article
Pimková Polidarová, Markéta - Břehová, Petra - Kaiser, Martin Maxmilian - Smola, Miroslav - Dračínský, Martin - Smith, Joshua - Marek, Aleš - Dejmek, Milan - Šála, Michal - Gutten, Ondrej - Rulíšek, Lubomír - Novotná, Barbora - Brázdová, Andrea - Janeba, Zlatko - Nencka, Radim - Bouřa, Evžen - Páv, Ondřej - Birkuš, Gabriel
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP).
Journal of Medicinal Chemistry. Roč. 64, č. 11 (2021), s. 7596-7616. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
Institutional support: RVO:61388963
Keywords : DNA sensor * interferon genes * cyclic GMP-AMP
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c00301
Permanent Link: http://hdl.handle.net/11104/0320799