Search results
- 1.0585351 - FGÚ 2025 RIV NL eng J - Journal Article
Bencze, Michal - Boroš, Almoš - Behuliak, Michal - Vavřínová, Anna - Vaněčková, Ivana - Zicha, Josef
Changes in cardiovascular autonomic control induced by chronic inhibition of acetylcholinesterase during pyridostigmine or donepezil treatment of spontaneously hypertensive rats.
European Journal of Pharmacology. Roč. 971, 15 May (2024), č. článku 176526. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA ČR(CZ) GA21-03810S
Institutional support: RVO:67985823
Keywords : parasympathetic tone * sympathetic tone * sympathovagal control of heart rate * spontaneously hypertensive rats * Wistar-Kyoto rats * acetylcholinesterase inhibitors
OECD category: Physiology (including cytology)
Impact factor: 5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.ejphar.2024.176526
Permanent Link: https://hdl.handle.net/11104/0353070File Download Size Commentary Version Access 24_0040_0585351.pdf 0 7.3 MB Publisher’s postprint open-access - 2.0583634 - BFÚ 2024 RIV US eng J - Journal Article
Kostrhunová, Hana - McGhie, B. S. - Marková, Lenka - Nováková, Olga - Kašpárková, Jana - Aldrich-Wright, J.R. - Brabec, Viktor
Platinum(IV) Derivatives of [Pt(1iS/i,2iS/i-diaminocyclohexane)(5,6-dimethyl-1,10-phenanthroline)] with Diclofenac Ligands in the Axial Positions: A New Class of Potent Multi-action Agents Exhibiting Selectivity to Cancer Cells.
Journal of Medicinal Chemistry. Roč. 66, č. 12 (2023), s. 7894-7908. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : cyclooxygenase inhibitors * anticancer activity * in-vitro * death * complexes * mechanism * cisplatin * mitochondrial * cytotoxicity
OECD category: Inorganic and nuclear chemistry
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00269
Permanent Link: https://hdl.handle.net/11104/0351654 - 3.0583286 - ÚOCHB 2025 RIV NL eng J - Journal Article
Khaleel, E. F. - Sabt, A. - Korycka-Machala, M. - Badi, R. M. - Son, N. T. - Ha, N. X. - Hamissa, Mohamed Farouk - Elsawi, A. E. - Elkaeed, E. B. - Dziadek, B. - Eldehna, W. M. - Dziadek, J.
Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA).
Bioorganic Chemistry. Roč. 144, March (2024), č. článku 107138. ISSN 0045-2068. E-ISSN 1090-2120
Institutional support: RVO:61388963
Keywords : biological activities * mycobacterium tuberculosis * InhA inhibitors * molecular docking * molecular dynamics Simulation
Impact factor: 5.1, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bioorg.2024.107138
Permanent Link: https://hdl.handle.net/11104/0351289 - 4.0580493 - BC 2024 RIV CH eng J - Journal Article
Martins, Larissa Almeida - Buša, Michal - Chlastáková, A. - Kotál, Jan - Beránková, Z. - Stergiou, N. - Jmel, Mohamed Amine - Schmitt, E. - Chmelař, J. - Mareš, Michael - Kotsyfakis, Michalis
Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host.
Cellular and Molecular Life Sciences. Roč. 80, č. 11 (2023), č. článku 339. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA ČR(CZ) GA19-07247S; GA MŠMT(CZ) EF16_019/0000759; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LTAUSA19109
Institutional support: RVO:60077344 ; RVO:61388963
Keywords : ray crystal-structure * sialostatin-l * functional expression * cysteine cathepsins * mammalian legumain * ixodes-scapularis * inhibitors * stefin * generation * peptidase * Ixodes ricinus * Tick saliva * Cystatins * Protease inhibition * Protein structure * Host-parasite interactions
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 8, year: 2022
Method of publishing: Limited access
https://link.springer.com/article/10.1007/s00018-023-04993-4
Permanent Link: https://hdl.handle.net/11104/0349268 - 5.0579727 - BC 2024 RIV CH eng J - Journal Article
Mikhnovets, I.E. - Holoubek, Jiří - Panina, I.S. - Kotouček, J. - Gvozdev, D.A. - Chumakov, S.P. - Krasilnikov, M.S. - Zhitlov, M.Y. - Gulyak, E.L. - Chistov, A.A. - Nikitin, T.D. - Korshun, V.A. - Efremov, R. G. - Alferova, V.A. - Růžek, Daniel - Eyer, Luděk - Ustinov, A.V.
Alkyl Derivatives of Perylene Photosensitizing Antivirals: Towards Understanding the Influence of Lipophilicity.
International Journal of Molecular Sciences. Roč. 24, č. 22 (2023), č. článku 16483. ISSN 1661-6596
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:60077344
Keywords : amphipathic fusion inhibitors * singlet oxygen generation * charmm force-field * photodynamic therapy * virus * gui * reproduction * dyes * antivirals * perylene * photosensitizers * singlet oxygen * lipophilicity
OECD category: Virology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/24/22/16483
Permanent Link: https://hdl.handle.net/11104/0348530File Download Size Commentary Version Access Mikhnovets_2023_IntJMolSci.pdf 1 5.8 MB Publisher’s postprint open-access - 6.0579099 - ÚMG 2024 RIV US eng J - Journal Article
Kutil, Z. - Mikešová, J. - Zessin, M. - Meleshin, M. - Nováková, Z. - Alquicer, Glenda - Kozikowski, A. - Sippl, W. - Bařinka, C. - Schutkowski, M.
Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors.
ACS Omega. Roč. 4, č. 22 (2019), s. 19895-19904. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : histone deacetylase inhibitors * sir2 family * posttranslational modifications * fluorescent-probe * peptide arrays * in-vitro * substrate-specificity * metabolic-regulation * fluorogenic probe * activity profiles
OECD category: Biochemistry and molecular biology
Impact factor: 2.870, year: 2019
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acsomega.9b02808
Permanent Link: https://hdl.handle.net/11104/0347965 - 7.0578957 - ÚOCHB 2024 RIV CZ eng A - Abstract
Král, Michal - Kotačka, Tomáš - Radilová, Kateřina - Gregor, Jiří - Machara, Aleš - Reiberger, Róbert - Kožíšek, Milan
Identification and characterization of polymerase inhibitors of L-protein of Rift Valley fever virus.
Czech Chemical Society Symposium Series. Roč. 21, č. 5 (2023), s. 183. ISSN 2336-7202.
[Annual meeting of the National Institute of Virology and Bacteriology (NIVB) /2./. 02.10.2023-05.10.2023, Kutná Hora]
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : Rift Valley fever virus * L-protein * polymerase inhibitors
OECD category: Virology
http://www.ccsss.cz/index.php/ccsss/issue/view/41/75
Permanent Link: https://hdl.handle.net/11104/0347857File Download Size Commentary Version Access NIVB Meeting 2023_L05.pdf 1 356.7 KB Publisher’s postprint open-access - 8.0578953 - ÚOCHB 2024 RIV CZ eng A - Abstract
Dejmek, Milan - Štefek, Milan - Otava, Tomáš - Misehe, Mbilo - Krafčíková, Petra - Klíma, Martin - Šála, Michal - Břehová, Petra - Bouřa, Evžen - Nencka, Radim
Novel antiviral strategies targeting methyltransferases, RIPK2, and STING pathway.
Czech Chemical Society Symposium Series. Roč. 21, č. 5 (2023), s. 182. ISSN 2336-7202.
[Annual meeting of the National Institute of Virology and Bacteriology (NIVB) /2./. 02.10.2023-05.10.2023, Kutná Hora]
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : methylstransferases * RIPK2 inhibitors * STING
OECD category: Virology
http://www.ccsss.cz/index.php/ccsss/issue/view/41/75
Permanent Link: https://hdl.handle.net/11104/0347856File Download Size Commentary Version Access NIVB Meeting 2023_L04.pdf 2 396 KB Publisher’s postprint open-access - 9.0576137 - ÚOCHB 2024 RIV US eng J - Journal Article
Inniss, N. L. - Kozic, Ján - Li, F. - Rosas-Lemus, M. - Minasov, G. - Rybáček, Jiří - Zhu, Y. - Pohl, Radek - Shuvalova, L. - Rulíšek, Lubomír - Brunzelle, J. S. - Bednárová, Lucie - Štefek, Milan - Kormaník, Ján Michael - Andris, Erik - Šebestík, Jaroslav - Li, A. S. M. - Brown, P. J. - Schmitz, U. - Saikatendu, K. - Chang, E. - Nencka, Radim - Vedadi, M. - Satchell, K. J. F.
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors.
ACS Infectious Diseases. Roč. 9, č. 10 (2023), s. 1918-1931. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : coronavirus * NSP16 methyltransferase * covalent inhibitors * structural biology * antiviral
OECD category: Virology
Impact factor: 5.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.3c00203
Permanent Link: https://hdl.handle.net/11104/0345731 - 10.0575380 - ÚOCHB 2024 RIV NL eng J - Journal Article
Spengler, J. R. - Carter, K. - Delang, L. - Durantel, D. - Gowen, B. B. - Herrero, L. J. - Hurst, B. - Janeba, Zlatko - Jordan, R. - Luo, D. - Meier, C. - Moffat, J. - Rocha-Pereira, J. - Seley-Radtke, K. L. - Welch, S. R. - Schang, L. M.
Meeting report: 36th International Conference on Antiviral Research in Lyon, France March 13-17, 2023.
Antiviral Research. Roč. 217, September (2023), č. článku 105678. ISSN 0166-3542. E-ISSN 1872-9096
Institutional support: RVO:61388963
Keywords : viruses * antivirals * inhibitors
OECD category: Virology
Impact factor: 7.6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.antiviral.2023.105678
Permanent Link: https://hdl.handle.net/11104/0345183