Search results
- 1.0570872 - ÚFCH JH 2024 RIV GB eng J - Journal Article
Pokorná, Šárka - Khersonsky, O. - Lipsh-Sokolik, R. - Goldenzweig, A. - Nielsen, R. - Ashani, Y. - Peleg, Y. - Unger, T. - Albeck, S. - Dym, O. - Tirosh, A. - Tarayra, R. - Hocquemiller, M. - Laufer, R. - Ben-Dor, S. - Silman, I. - Sussman, J. L. - Fleishman, S. J. - Futerman, A. H.
Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
FEBS Journal. Roč. 290, č. 13 (2023), s. 3383-3399. ISSN 1742-464X. E-ISSN 1742-4658
Institutional support: RVO:61388955
Keywords : Gaucher disease * gene therapy * in silico mutation classification * pross * Rosetta * SNPs
OECD category: Physical chemistry
Impact factor: 5.4, year: 2022
Method of publishing: Open access
Permanent Link: https://hdl.handle.net/11104/0342198File Download Size Commentary Version Access 0570872.pdf 0 1.6 MB open access Publisher’s postprint open-access - 2.0547646 - ÚEB 2022 RIV NL eng J - Journal Article
Manuka, R. - Saddhe, Ankush Ashok - Srivastava, A. K. - Kumar, K. - Penna, S.
Overexpression of rice OsWNK9 promotes arsenite tolerance in transgenic Arabidopsis plants.
Journal of Biotechnology. Roč. 332, MAY 20 (2021), s. 114-125. ISSN 0168-1656. E-ISSN 1873-4863
Institutional support: RVO:61389030
Keywords : Antioxidant enzymes * Arsenite * In silico * Overexpression * Rice * WNK
OECD category: Biochemistry and molecular biology
Impact factor: 3.595, year: 2021
Method of publishing: Open access
http://doi.org/10.1016/j.jbiotec.2021.04.001
Permanent Link: http://hdl.handle.net/11104/0323839File Download Size Commentary Version Access 2021_Manuka_JOURNAL OF BIOTECHNOLOGY_114.pdf 1 7 MB Other open-access - 3.0545882 - ÚEB 2022 RIV CH eng J - Journal Article
Al-Majmaie, S. - Nahar, Lutfun - Mukhlesur Rahman, M. - Nath, S. - Saha, P. - Talukdar, A. D. - Sharples, G. P. - Sarker, S. D.
Anti-MRSA Constituents from Ruta chalepensis (Rutaceae) Grown in Iraq, and In Silico Studies on Two of Most Active Compounds, Chalepensin and 6-Hydroxy-rutin 3 ',7-Dimethyl ether.
Molecules. Roč. 26, č. 4 (2021), č. článku 1114. E-ISSN 1420-3049
Institutional support: RVO:61389030
Keywords : Anti-MRSA * Chalepensin * In silico * Ruta chalepensis * Rutaceae * Rutin
OECD category: Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions (pharmacogenomics, gene-based therapeutics)
Impact factor: 4.927, year: 2021
Method of publishing: Open access
http://doi.org/10.3390/molecules26041114
Permanent Link: http://hdl.handle.net/11104/0322508File Download Size Commentary Version Access 2021_Al-Majmaie_MOLECULES_1114.pdf 1 4.4 MB Other open-access - 4.0541833 - ÚEM 2022 RIV CH eng J - Journal Article
Konečný, J. - Misiachna, Anna - Hrabinová, M. - Pulkrábková, L. - Benková, M. - Prchal, L. - Kučera, T. - Kobrlová, T. - Finger, V. - Kolcheva, Marharyta - Kortus, Štěpán - Jun, D. - Valko, M. - Horák, Martin - Soukup, O. - Korábečný, J.
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Biomolecules. Roč. 11, č. 1 (2021), č. článku 3. E-ISSN 2218-273X
R&D Projects: GA MZd(CZ) NU20-08-00296
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:68378041
Keywords : acetylcholinesterase * Alzheimer´s disease * butyrylcholinesterase * fluorene * in vitro * in silico * multi-target directed ligands * N-methyl-d-aspartate receptor
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/1/3
Permanent Link: http://hdl.handle.net/11104/0319349 - 5.0541685 - FGÚ 2022 RIV CH eng J - Journal Article
Konečný, J. - Misiachna, Anna - Hrabinová, M. - Pulkrábková, L. - Benková, M. - Prchal, L. - Kučera, T. - Kobrlová, T. - Finger, V. - Kolcheva, Marharyta - Kortus, Štěpán - Jun, D. - Valko, M. - Horák, Martin - Soukup, O. - Korábečný, J.
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Biomolecules. Roč. 11, č. 1 (2021), č. článku 3. E-ISSN 2218-273X
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:67985823
Keywords : acetylcholinesterase * Alzheimer´s disease * butyrylcholinesterase * fluorene * in vitro * in silico * multi-target directed ligands * N-methyl-d-aspartate receptor
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/1/3
Permanent Link: http://hdl.handle.net/11104/0319216 - 6.0538019 - ÚFCH JH 2021 RIV US eng J - Journal Article
Mohan, B. - Modi, Krunal M. - Patel, Ch. - Kumar, S. - Sharma, H. K.
Synthesis and computational mechanistic studies of copper selective molecular receptor.
Vietnam Journal of Chemistry. Roč. 58, č. 2 (2020), s. 221-230. ISSN 0866-7144. E-ISSN 2572-8288
R&D Projects: GA ČR GA17-18108S
Grant - others:GA MŠk(CZ) LM2015042
Institutional support: RVO:61388955
Keywords : fluorescent sensor * in-silico * complexes * recognition * chemosensor * Cu2+ Receptor * sensor * electronic transitions * Molecular Docking * Density Functional Theory
OECD category: Physical chemistry
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0315850File Download Size Commentary Version Access 0538019.pdf 5 1.4 MB Publisher’s postprint open-access - 7.0537480 - BC 2021 RIV US eng J - Journal Article
Hartigan, Ashlie - Kosakyan, Anush - Pecková, Hana - Eszterbauer, E. - Holzer, Astrid S.
Transcriptome ofSphaerospora molnari(Cnidaria, Myxosporea) blood stages provides proteolytic arsenal as potential therapeutic targets against sphaerosporosis in common carp.
BMC Genomics. Roč. 21, č. 1 (2020), č. článku 404. ISSN 1471-2164. E-ISSN 1471-2164
R&D Projects: GA ČR(CZ) GX19-28399X
EU Projects: European Commission(XE) 634429 - ParaFishControl
Institutional support: RVO:60077344
Keywords : signal peptide peptidase * matrix metalloproteinases * cysteine protease * malaria parasite * gene-expression * drug target * cathepsin-l * sp-nov * identification * myxozoa * Myxozoa * In silico screening * Proteases * Aquaculture * Parasite * Drug targets
OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Impact factor: 3.969, year: 2020
Method of publishing: Open access
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-020-6705-y
Permanent Link: http://hdl.handle.net/11104/0315288 - 8.0532722 - ÚEB 2021 RIV IN eng J - Journal Article
Savić, M. P. - Kuzminac, I. Z. - Škorić, D. - Jakimov, D. S. - Rárová, Lucie - Sakač, M. N. - Djurendić, E. A.
New oxygen-containing androstane derivatives: Synthesis and biological potential.
Journal of chemical sciences. Roč. 132, č. 1 (2020), č. článku 98. ISSN 0974-3626. E-ISSN 0973-7103
Institutional support: RVO:61389030
Keywords : cytotoxicity * D-homo androstane lactones * in silico ADME studies * NMR analysis
OECD category: Biochemistry and molecular biology
Impact factor: 1.573, year: 2020
Method of publishing: Open access
http://doi.org/10.1007/s12039-020-01803-3
Permanent Link: http://hdl.handle.net/11104/0311134File Download Size Commentary Version Access 2020_Savic_JOURNAL OF CHEMICAL SCIENCES_98.pdf 1 748.3 KB Other open-access - 9.0531546 - ÚOCHB 2021 RIV DE eng J - Journal Article
Pecina, Adam - Eyrilmez, Saltuk M. - Köprülüoglu, Cemal - Miriyala, Vijay Madhav - Lepšík, Martin - Fanfrlík, Jindřich - Řezáč, Jan - Hobza, Pavel
SQM/COSMO Scoring Function: Reliable Quantum-Mechanical Tool for Sampling and Ranking in Structure-Based Drug Design.
ChemPlusChem. Roč. 85, č. 11 (2020), s. 2362-2371. ISSN 2192-6506. E-ISSN 2192-6506
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : in silico drug design * protein-ligand binding * quantum mechanics * semiempirical methods * virtual screening
OECD category: Physical chemistry
Impact factor: 2.863, year: 2020
Method of publishing: Limited access
https://doi.org/10.1002/cplu.202000120
Permanent Link: http://hdl.handle.net/11104/0310179 - 10.0531060 - ÚEB 2021 RIV US eng J - Journal Article
Savić, M. P. - Škorić, D. - Kuzminac, I. Z. - Jakimov, D. S. - Kojić, V. V. - Rárová, Lucie - Strnad, Miroslav - Djurendić, E. A.
New A-homo lactam D-homo lactone androstane derivative: Synthesis and evaluation of cytotoxic and anti-inflammatory activities in vitro.
Steroids. Roč. 157, MAY (2020), č. článku 108596. ISSN 0039-128X. E-ISSN 1878-5867
R&D Projects: GA ČR(CZ) GA19-01383S
Institutional support: RVO:61389030
Keywords : ADME analysis in silico * Anti-angiogenic activity * Anti-inflammatory activity * Apoptotic morphology * Cytotoxic activity * Structural analysis
OECD category: Organic chemistry
Impact factor: 2.668, year: 2020
Method of publishing: Open access
http://doi.org/10.1016/j.steroids.2020.108596
Permanent Link: http://hdl.handle.net/11104/0309810File Download Size Commentary Version Access 2020_Savic_STEROIDS_108596.pdf 1 1.1 MB Other open-access