Search results
- 1.0547169 - ÚOCHB 2022 RIV CH eng J - Journal Article
Majerová, Taťána - Novotný, Pavel
Precursors of Viral Proteases as Distinct Drug Targets.
Viruses. Roč. 13, č. 10 (2021), č. článku 1981. E-ISSN 1999-4915
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : protease * autoprocessing * precursor * activation * Human Immunodeficiency Virus (HIV) * Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) * herpesviruses * adenoviruses * flaviviruses
OECD category: Biochemistry and molecular biology
Impact factor: 5.818, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/v13101981
Permanent Link: http://hdl.handle.net/11104/0323489 - 2.0544834 - ÚMG 2022 RIV US eng J - Journal Article
Kryštůfek, R. - Šácha, P. - Starková, J. - Brynda, Jiří - Hradilek, M. - Tloušťová, E. - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, P. - Hájek, M. - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, J.
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:68378050
Keywords : immunodeficiency-virus hiv * in-vitro * virulence factors * type-1 protease * inhibitors * pepsin * specificity * meningitis * expression * strategies
OECD category: Biochemistry and molecular biology
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0321646 - 3.0543118 - ÚOCHB 2022 RIV US eng J - Journal Article
Kryštůfek, Robin - Šácha, Pavel - Starková, Jana - Brynda, Jiří - Hradilek, Martin - Tloušťová, Eva - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, Pavel - Hájek, Miroslav - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, Jan
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : immunodeficiency virus HIV * in-vitro * virulence factors
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0320402 - 4.0464300 - ÚOCHB 2017 RIV FR eng J - Journal Article
Šimon, Petr - Baszczyňski, Ondřej - Šaman, David - Stepan, G. - Hu, E. - Lansdon, E. B. - Jansa, P. - Janeba, Zlatko
Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl) methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1.
European Journal of Medicinal Chemistry. Roč. 122, Oct 21 (2016), s. 185-195. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:61388963
Keywords : diarylpyrimidine (DAPY) * etravirine * human immunodeficiency virus (HIV) * non-nucleoside reverse transcriptase inhibitors * NNRTIs * rilpivirine
Subject RIV: CC - Organic Chemistry
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263235