Search results
- 1.0565334 - ÚOCHB 2023 RIV NL eng J - Journal Article
Majerová, Taťána - Konvalinka, Jan
Viral proteases as therapeutic targets.
Molecular Aspects of Medicine. Roč. 88, December (2022), č. článku 101159. ISSN 0098-2997. E-ISSN 1872-9452
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : hepatitis C virus * human immunodeficiency virus * orally bioavailable inhibitor
OECD category: Virology
Impact factor: 10.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.mam.2022.101159
Permanent Link: https://hdl.handle.net/11104/0336883File Download Size Commentary Version Access 10.1016j.mam.2022.101159.pdf 4 8.1 MB Publisher’s postprint open-access - 2.0547169 - ÚOCHB 2022 RIV CH eng J - Journal Article
Majerová, Taťána - Novotný, Pavel
Precursors of Viral Proteases as Distinct Drug Targets.
Viruses. Roč. 13, č. 10 (2021), č. článku 1981. E-ISSN 1999-4915
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : protease * autoprocessing * precursor * activation * Human Immunodeficiency Virus (HIV) * Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) * herpesviruses * adenoviruses * flaviviruses
OECD category: Biochemistry and molecular biology
Impact factor: 5.818, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/v13101981
Permanent Link: http://hdl.handle.net/11104/0323489 - 3.0518189 - ÚOCHB 2020 RIV GB eng J - Journal Article
Čechová, Lucie - Dejmek, Milan - Baszczyňski, Ondřej - Šaman, David - Gao, L. - Hu, E. - Stepan, G. - Jansa, P. - Janeba, Zlatko - Šimon, Petr
Synthesis and anti-human immunodeficiency virus activity of substituted (o,o-difluorophenyl)-linked-pyrimidines as potent non‐nucleoside reverse transcriptase inhibitors.
Antiviral Chemistry and Chemotherapy. Roč. 27, Feb 6 (2019), s. 1-18. ISSN 0956-3202
Institutional support: RVO:61388963
Keywords : diarylpyrimidine * human immunodeficiency virus * non-nucleoside reverse transcriptase inhibitor * etravirine * rilpivirine
OECD category: Organic chemistry
Method of publishing: Open access
https://journals.sagepub.com/doi/full/10.1177/2040206619826265
Permanent Link: http://hdl.handle.net/11104/0303424 - 4.0492282 - ÚOCHB 2019 RIV GB eng J - Journal Article
Humpolíčková, Jana - Weber, Jan - Starková, Jana - Mašínová, Eva - Günterová, Jana - Flaisigová, Iva - Konvalinka, Jan - Majerová, Taťána
Inhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation.
Scientific Reports. Roč. 8, Jul 11 (2018), č. článku 10438. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : human immunodeficiency virus * type 1 GagPol precursor * conformational ensembles
OECD category: Biochemistry and molecular biology
Impact factor: 4.011, year: 2018
https://www.nature.com/articles/s41598-018-28638-w
Permanent Link: http://hdl.handle.net/11104/0285806File Download Size Commentary Version Access 0492282.pdf 5 1.8 MB Publisher’s postprint open-access - 5.0490465 - ÚOCHB 2019 RIV US eng J - Journal Article
Dostálková, A. - Kaufman, F. - Křížová, I. - Kultová, A. - Strohalmová, K. - Hadravová, Romana - Ruml, T. - Rumlová, M.
Mutations in the Basic Region of the Mason-Pfizer Monkey Virus Nucleocapsid Protein Affect Reverse Transcription, Genomic RNA Packaging, and the Virus Assembly Site.
Journal of Virology. Roč. 92, č. 10 (2018), č. článku e00106-18. ISSN 0022-538X. E-ISSN 1098-5514
Institutional support: RVO:61388963
Keywords : M-PMV * RNA packaging * assembly * basic residues * human immunodeficiency virus * infectivity
OECD category: Virology
Impact factor: 4.324, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284700 - 6.0487081 - ÚMG 2018 RIV GB eng J - Journal Article
Šenigl, Filip - Miklík, Dalibor - Auxt, Miroslav - Hejnar, Jiří
Accumulation of long-term transcriptionally active integrated retroviral vectors in active promoters and enhancers.
Nucleic Acids Research. Roč. 45, č. 22 (2017), s. 12752-12765. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA14-34873S; GA MŠMT LO1419
Institutional support: RVO:68378050
Keywords : human-immunodeficiency-virus * dna methylation * site selection * human genome * avian-sarcoma * morphological reversion * hiv-1 integration * mlv integration * gene-expression * leukosis virus
OECD category: Virology
Impact factor: 11.561, year: 2017
Permanent Link: http://hdl.handle.net/11104/0281763File Download Size Commentary Version Access Nucleic_Acids_Research_F_Senigl_2017.pdf 2 1.2 MB Publisher’s postprint require - 7.0486050 - BFÚ 2018 RIV US eng J - Journal Article
Figiel, M. - Krepl, Miroslav - Park, S. - Poznanski, J. - Skowronek, K. - Golab, A. - Ha, T. - Šponer, Jiří - Nowotny, M.
Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase.
Journal of Biological Chemistry. Roč. 293, č. 1 (2018), s. 191-202. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GBP305/12/G034
Institutional support: RVO:68081707
Keywords : human-immunodeficiency-virus * strand dna-synthesis * retroviral rnases-h * rna/dna hybrid
OECD category: Biochemistry and molecular biology
Impact factor: 4.106, year: 2018
Permanent Link: http://hdl.handle.net/11104/0280938 - 8.0476541 - BFÚ 2018 RIV GB eng J - Journal Article
Figiel, M. - Krepl, Miroslav - Poznanski, J. - Gotab, A. - Šponer, Jiří - Nowotny, M.
Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase.
Nucleic Acids Research. Roč. 45, č. 6 (2017), s. 3341-3352. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR GAP208/12/1878
Grant - others:GA MŠk(CZ) LO1305
Institutional support: RVO:68081707
Keywords : human-immunodeficiency-virus * rna/dna hybrid * force-field
OECD category: Biochemistry and molecular biology
Impact factor: 11.561, year: 2017
Permanent Link: http://hdl.handle.net/11104/0273021 - 9.0464300 - ÚOCHB 2017 RIV FR eng J - Journal Article
Šimon, Petr - Baszczyňski, Ondřej - Šaman, David - Stepan, G. - Hu, E. - Lansdon, E. B. - Jansa, P. - Janeba, Zlatko
Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl) methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1.
European Journal of Medicinal Chemistry. Roč. 122, Oct 21 (2016), s. 185-195. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:61388963
Keywords : diarylpyrimidine (DAPY) * etravirine * human immunodeficiency virus (HIV) * non-nucleoside reverse transcriptase inhibitors * NNRTIs * rilpivirine
Subject RIV: CC - Organic Chemistry
Impact factor: 4.519, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263235 - 10.0463946 - ÚOCHB 2017 RIV GB eng J - Journal Article
Čermáková, Kateřina - Weydert, C. - Christ, F. - De Rijck, J. - Debyser, Z.
Lessons Learned: HIV Points tie Way Towards Precision Treatment of Mixed-Lineage Leukemia.
Trends in Pharmacological Sciences. Roč. 37, č. 8 (2016), s. 660-671. ISSN 0165-6147. E-ISSN 1873-3735
R&D Projects: GA ČR(CZ) GA16-06357S; GA MŠMT(CZ) LK11205
Institutional support: RVO:61388963
Keywords : human immunodeficiency virus * transcriptional coactivator p75 * acute lymphoblastic leukemia
Subject RIV: CE - Biochemistry
Impact factor: 12.797, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263023