Search results

  1. 1.
    0559713 - ÚOCHB 2023 RIV US eng J - Journal Article
    Vymětal, Jiří - Mertová, Kateřina - Boušová, Kristýna - Šulc, Josef - Tripsianes, K. - Vondrášek, Jiří
    Fusion of two unrelated protein domains in a chimera protein and its 3D prediction: Justification of the x-ray reference structures as a prediction benchmark.
    Proteins-Structure, Function and Bioinformatics. Roč. 90, č. 12 (2022), s. 2067-2079. ISSN 0887-3585. E-ISSN 1097-0134
    R&D Projects: GA MŠMT(CZ) LM2018131; GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA19-03488S
    Research Infrastructure: e-INFRA CZ - 90140
    Institutional support: RVO:61388963
    Keywords : 3D structure prediction * fusion proteins * molecular simulations * X-ray crystallography
    OECD category: Biochemistry and molecular biology
    Impact factor: 2.9, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1002/prot.26398
    Permanent Link: https://hdl.handle.net/11104/0332921
     
     
  2. 2.
    0546460 - FGÚ 2022 RIV CH eng J - Journal Article
    Randáková, Alena - Nelic, Dominik - Hochmalová, Martina - Zimčík, Pavel - Mulenga, Mutale Jane - Boulos, J. - Jakubík, Jan
    Fusion with Promiscuous G alpha(16) Subunit Reveals Signaling Bias at Muscarinic Receptors.
    International Journal of Molecular Sciences. Roč. 22, č. 18 (2021), č. článku 10089. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GJ19-06106Y
    Institutional support: RVO:67985823
    Keywords : muscarinic receptors * signaling bias * fusion proteins * non-canonical signaling
    OECD category: Pharmacology and pharmacy
    Impact factor: 6.208, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/22/18/10089
    Permanent Link: http://hdl.handle.net/11104/0322964
     
     
  3. 3.
    0536182 - ÚFCH JH 2021 RIV US eng J - Journal Article
    Štefl, Martin - Herbst, K. - Ruebsam, M. - Benda, Aleš - Knop, M.
    Single-Color Fluorescence Lifetime Cross-Correlation Spectroscopy In Vivo.
    Biophysical Journal. Roč. 119, č. 7 (2020), s. 1359-1370. ISSN 0006-3495. E-ISSN 1542-0086
    R&D Projects: GA ČR(CZ) GJ19-08304Y
    Institutional support: RVO:61388955
    Keywords : protein-protein interactions * saccharomyces-cerevisiae * fusion proteins * yeast genes * green * molecules * proteasome * microscopy * chromophore * technology
    OECD category: Physical chemistry
    Impact factor: 4.033, year: 2020
    Method of publishing: Limited access
    Permanent Link: http://hdl.handle.net/11104/0313996
    FileDownloadSizeCommentaryVersionAccess
    0536182.pdf21.5 MBPublisher’s postprintrequire
     
     
  4. 4.
    0487349 - ÚMG 2018 RIV GB eng J - Journal Article
    Zimmermannova, O. - Doktorova, E. - Stuchlý, J. - Kanderová, V. - Kuzilkova, D. - Strnad, Hynek - Starková, J. - Alberich-Jorda, Meritxell - Falkenburg, J.H.F. - Trka, J. - Petrák, J. - Zuna, J. - Žaliová, M.
    An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia.
    Oncogene. Roč. 36, č. 43 (2017), s. 5985-5994. ISSN 0950-9232. E-ISSN 1476-5594
    R&D Projects: GA ČR(CZ) GBP302/12/G101; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:68378050
    Keywords : acute lymphoblastic-leukemia * chronic myeloid-leukemia * bcr-abl * tel-abl * cytogenetic characterization * imatinib-mesylate * fusion proteins * blast crisis * rearrangement * patient
    OECD category: Cell biology
    Impact factor: 6.854, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0282003
     
     
  5. 5.
    0471866 - ÚMG 2017 RIV US eng J - Journal Article
    Kanderová, V. - Kuzilkova, D. - Stuchlý, J. - Vašková, M. - Brdička, Tomáš - Fišer, K. - Hrušák, O. - Lund-Johansen, F. - Kalina, T.
    High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells.
    Molecular & Cellular Proteomics. Roč. 15, č. 4 (2016), s. 1246-1261. ISSN 1535-9476. E-ISSN 1535-9484
    R&D Projects: GA MŠMT 2B06064
    Institutional support: RVO:68378050
    Keywords : acute lymphoblastic-leukemia * acute promyelocytic leukemia * cytometric immunobead assay * caspase-dependent cleavage * acute myeloid-leukemia * gene-expression * fusion proteins * flow-cytometry * pcr data * b-cells
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 6.540, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0269224
     
     
  6. 6.
    0467009 - ÚOCHB 2017 RIV US eng J - Journal Article
    Palani, Kirubakaran - Pfeiferová, Lucie - Boušová, Kristýna - Bednárová, Lucie - Obšilová, V. - Vondrášek, Jiří
    Artificial proteins as allosteric modulators of PDZ3 and SH3 in two-domain constructs: A computational characterization of novel chimeric proteins.
    Proteins-Structure, Function and Bioinformatics. Roč. 84, č. 10 (2016), s. 1358-1374. ISSN 0887-3585. E-ISSN 1097-0134
    Institutional support: RVO:61388963
    Keywords : protein design * fusion proteins * PDZ3 * SH3 * Trp-cage * two domain proteins
    Subject RIV: CE - Biochemistry
    Impact factor: 2.289, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0265168
     
     
  7. 7.
    0463459 - FGÚ 2017 RIV US eng J - Journal Article
    Palani, K. - Pfeiferová, L. - Boušová, Kristýna - Bednárová, L. - Obšilová, Veronika - Vondrášek, J.
    Artificial proteins as allosteric modulators of PDZ3 and SH3 in two-domain constructs: A computational characterization of novel chimeric proteins.
    Proteins-Structure, Function and Bioinformatics. Roč. 84, č. 10 (2016), s. 1358-1374. ISSN 0887-3585. E-ISSN 1097-0134
    Institutional support: RVO:67985823
    Keywords : protein design * fusion proteins * PDZ3 * SH3 * Trp-cage * two domain proteins * molecular dynamics simulation * circular dichroism
    Subject RIV: BO - Biophysics
    Impact factor: 2.289, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0262657
     
     
  8. 8.
    0460390 - ÚOCHB 2017 US eng A - Abstract
    Palani, Kirubakaran - Pfeiferová, Lucie - Vondrášek, Jiří
    Mapping Allostery in the Two Domain Constructs of PDZ3 and SH3 with Artificial Domains.
    Biophysical Journal. Cell Press. Roč. 110, Suppl 1 (2016), 52A. ISSN 0006-3495. E-ISSN 1542-0086.
    [Annual Meeting of the Biophysical Society /60./. 27.02.2016-02.03.2016, Los Angeles]
    Institutional support: RVO:61388963
    Keywords : fusion proteins * molecular dynamics simulations
    Subject RIV: BO - Biophysics
    Permanent Link: http://hdl.handle.net/11104/0260492
     
     
  9. 9.
    0459987 - ÚOCHB 2017 CZ eng A - Abstract
    Palani, Kirubakaran - Pfeiferová, Lucie - Vondrášek, Jiří
    Mapping allostery in the two domain constructs of PDZ3 and SH3 with artificial domains.
    Prague Protein Spring Meeting 2016: Proteins and their Design. Praha: Ústav organické chemie a biochemie AV ČR, 2016. s. 77. ISBN 978-80-86241-55-5.
    [Prague Protein Spring Meeting 2016: Proteins and their Design /4./. 05.05.2016-08.05.2016, Praha]
    Institutional support: RVO:61388963
    Keywords : fusion proteins * molecular dynamics simulations
    Subject RIV: CF - Physical ; Theoretical Chemistry
    Permanent Link: http://hdl.handle.net/11104/0260133
     
     
  10. 10.
    0348877 - ÚVGZ 2011 RIV TR eng J - Journal Article
    Šafařík, Ivo - Šafaříková, Miroslava
    Magnetic affinity separation of recombinant fusion proteins.
    Hacettepe Journal of Biology and Chemistry. Roč. 38, č. 1 (2010), s. 1-7. ISSN 1303-5002
    R&D Projects: GA MŠMT(CZ) OC 157; GA MPO(CZ) 2A-1TP1/094
    Institutional research plan: CEZ:AV0Z60870520
    Keywords : recombinant fusion proteins * affinity tags * magnetic separation
    Subject RIV: CE - Biochemistry
    Permanent Link: http://hdl.handle.net/11104/0189282
     
     

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