Search results

  1. 1.
    0567637 - ÚMCH 2024 RIV NL eng J - Journal Article
    Tezcan, O. - Elshafei, A. S. - Benderski, K. - Rama, E. - Wagner, M. - Moeckel, D. - Pola, Robert - Pechar, Michal - Etrych, Tomáš - von Stillfried, S. - Kiessling, F. - Weiskirchen, R. - Meurer, S. - Lammers, T.
    Effect of cellular and microenvironmental multidrug resistance on tumor-targeted drug delivery in triple-negative breast cancer.
    Journal of Controlled Release. Roč. 354, February (2023), s. 784-793. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA MŠMT(CZ) LTAUSA18083; GA ČR(CZ) GA22-12483S
    Institutional support: RVO:61389013
    Keywords : nanomedicine * drug targeting * EPR effect
    OECD category: Polymer science
    Impact factor: 10.8, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0168365922008707?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0339703
     
     
  2. 2.
    0550965 - FGÚ 2022 RIV IN eng M - Monography Chapter
    Hagenbuchner, J. - Obšilová, Veronika - Obexer, P. - Obšil, Tomáš - Ausserlechner, M. J.
    Discovery of Small Compounds that Target FOXO Transcription Factors and Modulate their Transcriptional Activity and Physiological Function.
    New Innovations in Chemistry and Biochemistry. Vol. 4. Hoogly: B P International, 2021 - (Romero Martínez, A.), s. 41-54. ISBN 978-93-5547-113-0
    Institutional support: RVO:67985823
    Keywords : drug-targeting * FOX proteins * FOXO transcription factors * small compounds
    OECD category: Biochemistry and molecular biology
    https://doi.org/10.9734/bpi/nicb/v4/14349D
    Permanent Link: http://hdl.handle.net/11104/0326251
     
     
  3. 3.
    0518629 - FGÚ 2020 RIV GB eng J - Journal Article
    Hagenbuchner, J. - Obšilová, Veronika - Kaserer, T. - Kaiser, N. - Rass, B. - Pšenáková, Katarína - Dočekal, V. - Alblová, Miroslava - Kohoutová, Klára - Schuster, D. - Aneichyk, T. - Veselý, J. - Obexer, P. - Obšil, Tomáš - Ausserlechner, M. J.
    Modulating FOXO3 transcriptional activity by small, DBD-binding molecules.
    eLife. Roč. 8, Dec 4 (2019), č. článku e48876. ISSN 2050-084X. E-ISSN 2050-084X
    R&D Projects: GA ČR(CZ) GF17-33854L
    Institutional support: RVO:67985823
    Keywords : small compounds * drug-targeting * FOXO transcription factors * FOX proteins
    OECD category: Biochemistry and molecular biology
    Impact factor: 7.080, year: 2019
    Method of publishing: Open access
    https://elifesciences.org/articles/48876
    Permanent Link: http://hdl.handle.net/11104/0303731
     
     
  4. 4.
    0506084 - ÚMCH 2020 CZ eng A - Abstract
    Pechar, Michal - Pola, Robert - Filippov, Sergey K. - Etrych, Tomáš - Král, Vlastimil - Sieglová, Irena - Fábry, Milan
    Polymer cancerostatics targeted to GD2-positive tumors via recombinant antibody fragments.
    Book of Abstracts and Programme. Prague: Institute of Macromolecular Chemistry, Czech Academy of Sciences, 2019. s. 110. ISBN 978-80-85009-93-4.
    [Polymers in Medicine 2019 - Prague Meeting on Macromolecules /83./. 23.06.2019-27.06.2019, Prague]
    R&D Projects: GA MŠMT(CZ) LO1507
    Institutional support: RVO:61389013 ; RVO:68378050
    Keywords : polymer therapeutics * drug targeting * recombinant proteins
    OECD category: Polymer science; Biochemical research methods (UMG-J)
    Permanent Link: http://hdl.handle.net/11104/0297496
     
     
  5. 5.
    0505611 - ÚMCH 2020 GR eng A - Abstract
    Pechar, Michal - Král, Vlastimil - Pola, Robert - Filippov, Sergey K. - Sieglová, Irena - Fábry, Milan - Etrych, Tomáš
    Targeting of polymer cancerostatics to GD2-positive tumor cells using recombinant antibody fragments.
    Abstract Book. Heraklion: European Polymer Federation, 2019. s. 208.
    [European Polymer Congress 2019 - EPF 2019. 09.06.2019-14.06.2019, Heraklion]
    R&D Projects: GA MŠMT(CZ) LO1507
    Institutional support: RVO:61389013 ; RVO:68378050
    Keywords : polymer therapeutics * drug targeting * recombinant proteins
    OECD category: Polymer science; Biochemical research methods (UMG-J)
    Permanent Link: http://hdl.handle.net/11104/0297434
     
     
  6. 6.
    0499714 - ÚMCH 2020 RIV US eng J - Journal Article
    Pola, Robert - Král, Vlastimil - Filippov, Sergey K. - Kaberov, Leonid I. - Etrych, Tomáš - Sieglová, Irena - Sedláček, Juraj - Fábry, Milan - Pechar, Michal
    Polymer cancerostatics targeted by recombinant antibody fragments to GD2-positive tumor cells.
    Biomacromolecules. Roč. 20, č. 1 (2019), s. 412-421. ISSN 1525-7797. E-ISSN 1526-4602
    R&D Projects: GA ČR(CZ) GA16-17207S; GA MZd(CZ) NV16-28594A; GA MPO FV10312
    Institutional support: RVO:61389013 ; RVO:68378050
    Keywords : polymer cancerostatics * drug targeting * scFv
    OECD category: Polymer science; Biochemical research methods (UMG-J)
    Impact factor: 6.092, year: 2019
    Method of publishing: Limited access
    https://pubs.acs.org/doi/10.1021/acs.biomac.8b01616
    Permanent Link: http://hdl.handle.net/11104/0292360
     
     
  7. 7.
    0493172 - ÚMCH 2019 SE eng A - Abstract
    Pechar, Michal - Pola, Robert - Janoušková, Olga - Král, Vlastimil - Sieglová, Irena - Fábry, Milan
    Non-covalent methods of attachment of recombinant proteins to polymer therapeutics.
    Proceedings & Abstracts Book. Stockholm: International Association of Advanced Materials, 2018. s. 11. ISBN 978-91-88252-13-5.
    [Sensors and Actuators Congress. 03.09.2018-06.09.2018, Stockholm]
    R&D Projects: GA ČR(CZ) GA16-17207S
    Institutional support: RVO:61389013 ; RVO:68378050
    Keywords : polymer therapeutics * drug targeting * recombinant proteins
    OECD category: Polymer science; Biochemical research methods (UMG-J)
    Permanent Link: http://hdl.handle.net/11104/0287376
     
     
  8. 8.
    0484884 - ÚMCH 2019 RIV DE eng J - Journal Article
    Pechar, Michal - Pola, Robert - Janoušková, Olga - Sieglová, Irena - Král, Vlastimil - Fábry, Milan - Tomalová, Barbora - Kovář, Marek
    Polymer cancerostatics targeted with an antibody fragment bound via a coiled coil motif: in vivo therapeutic efficacy against murine BCL1 leukemia.
    Macromolecular Bioscience. Roč. 18, č. 1 (2018), s. 1-11, č. článku 1700173. ISSN 1616-5187. E-ISSN 1616-5195
    R&D Projects: GA MŠMT(CZ) LO1507; GA MŠMT(CZ) LQ1604; GA MZd(CZ) NV16-28594A; GA ČR(CZ) GA16-17207S; GA ČR GA13-12885S
    Institutional support: RVO:61389013 ; RVO:68378050 ; RVO:61388971
    Keywords : cancer therapy * coiled coil * drug targeting
    OECD category: Polymer science; Biochemical research methods (UMG-J); Microbiology (MBU-M)
    Impact factor: 2.895, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0280967
     
     
  9. 9.
    0469013 - ÚMCH 2017 RIV eng P - Patent Document
    Etrych, Tomáš - Chytil, Petr - Strohalm, Jiří - Ulbrich, Karel - Říhová, Blanka
    Dendritic high-molecular-weight polymer drug carriers and their conjugates with drugs for treatment of solid tumours.
    2015. Owner: Ústav makromolekulární chemie AV ČR, v. v. i. - Mikrobiologický ústav AV ČR, v. v. i. Date of the patent acceptance: 22.12.2015. Patent Number: CA2783393
    R&D Projects: GA AV ČR IAA400500806; GA AV ČR KAN200200651
    Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z50200510
    Keywords : polymer conjugates * doxorubicin * drug targeting
    Subject RIV: CD - Macromolecular Chemistry; FR - Pharmacology ; Medidal Chemistry (MBU-M)
    http://www.ic.gc.ca/opic-cipo/cpd/eng/patent/2783393/summary.html?type=number_search&tabs1Index=tabs1_1
    Permanent Link: http://hdl.handle.net/11104/0266915
     
     
  10. 10.
    0467485 - ÚMCH 2017 RIV NL eng J - Journal Article
    Hu, Q. - Rijcken, C. J. F. - van Gaal, E. - Brundel, P. - Kostková, Hana - Etrych, Tomáš - Weber, B. - Barz, M. - Kiessling, F. - Prakash, J. - Storm, G. - Hennink, W. E. - Lammers, T.
    Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications.
    Journal of Controlled Release. Roč. 244, Part B (2016), s. 314-325. ISSN 0168-3659. E-ISSN 1873-4995.
    [European Symposium on Controlled Drug Delivery /14./. Egmond aan Zee, 13.04.2016-15.04.2016]
    Institutional support: RVO:61389013
    Keywords : nanomedicine * drug targeting * polymeric micelles
    Subject RIV: CD - Macromolecular Chemistry
    Impact factor: 7.786, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0266386
     
     

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