Search results
- 1.0574540 - BTÚ 2024 RIV GB eng J - Journal Article
Feng, J. - Neužil, Jiří - Manz, A. - Iliescu, C. - Neužil, P.
Microfluidic trends in drug screening and drug delivery.
TrAC-Trends in Analytical Chemistry. Roč. 158, JAN 2023 (2023), č. článku 116821. ISSN 0165-9936. E-ISSN 1879-3142
Institutional support: RVO:86652036
Keywords : Microfluidic technologies * Drug screening * Drug delivery * Drug discovery
OECD category: Analytical chemistry
Impact factor: 13.1, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0165993622003041?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0345464 - 2.0569551 - BTÚ 2023 RIV GB eng J - Journal Article
Kumar, S. - Kumar, G. S. - Maitra, S. S. - Malý, Petr - Bharadwaj, Shiv - Sharma, P. - Dwivedi, V. D.
Viral informatics: bioinformatics-based solution for managing viral infections.
Briefings in Bioinformatics. Roč. 23, č. 5 (2022), č. článku 326. ISSN 1467-5463. E-ISSN 1477-4054
Institutional support: RVO:86652036
Keywords : viral informatics * viral pandemic * drug discovery * vaccine development * artificial intelligence
OECD category: Biochemical research methods
Impact factor: 9.5, year: 2022
Method of publishing: Open access
https://academic.oup.com/bib/article/23/5/bbac326/6659740?login=true
Permanent Link: https://hdl.handle.net/11104/0340913 - 3.0560734 - BC 2023 RIV NL eng J - Journal Article
Chakroborty, Anand - Pritchard, D. - Bouillon, M.E. - Cervi, A. - Cookson, A. - Wild, C. - Fenn, C. - Payne, J. - Holdsworth, P. - Capner, C. - O'Neill, J. - Padalino, G. - Gupta, A. - Smith, B.G. - Fisher, M. - Lahmann, M. - Baird, M.S. - Hoffmann, K.F.
Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.
Veterinary Parasitology. Roč. 309, SEP (2022), č. článku 109766. ISSN 0304-4017. E-ISSN 1873-2550
Institutional support: RVO:60077344
Keywords : Fasciola hepatica * Triclabendazole * Anthelmintic drug discovery * Abietic acid * Diterpene and dehydroabietic acid
OECD category: Veterinary science
Impact factor: 2.6, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0304401722001200?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0339322 - 4.0555025 - BC 2022 RIV CH eng J - Journal Article
Sojka, Daniel - Šnebergerová, Pavla - Robbertse, Luise
Protease Inhibition-An Established Strategy to Combat Infectious Diseases.
International Journal of Molecular Sciences. Roč. 22, č. 11 (2021), č. článku 5762. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA20-05736S; GA MŠMT(CZ) EF16_019/0000759
Institutional support: RVO:60077344
Keywords : plasmodium-falciparum * plasmepsin-v * malaria parasites * drug discovery * potent * validation * proteins * invasion * egress * target * protease * parasites * inhibition * therapy * infectious diseases
OECD category: Immunology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/11/5762
Permanent Link: http://hdl.handle.net/11104/0329643 - 5.0554120 - BC 2022 RIV CH eng J - Journal Article
Jmel, Mohamed Amine - Aounallah, H. - Bensaoud, Chaima - Mekki, Imen - Chmelař, J. - Faria, F. - M'ghirbi, Y. - Kotsyfakis, Michalis
Insights into the Role of Tick Salivary Protease Inhibitors during Ectoparasite-Host Crosstalk.
International Journal of Molecular Sciences. Roč. 22, č. 2 (2021), č. článku 892. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-07247S
Institutional support: RVO:60077344
Keywords : bowman-birk inhibitor * serine-proteases * proteinase-inhibitors * ixodes-scapularis * sialostatin-l * amblyomin-x * cysteine proteases * trypsin-inhibitor * anticoagulant peptide * boophilus-microplus * protease inhibitors * proteases * tick saliva * drug discovery
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/2/892
Permanent Link: http://hdl.handle.net/11104/0328756 - 6.0547316 - ÚOCHB 2022 RIV DE eng J - Journal Article
Mancuso, F. - De Luca, L. - Bucolo, F. - Vrábel, Milan - Angeli, A. - Capasso, C. - Supuran, C. T. - Gitto, R.
4-Sulfamoylphenylalkylamides as Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae.
ChemMedChem. Roč. 16, č. 24 (2021), s. 3787-3794. ISSN 1860-7179. E-ISSN 1860-7187
Institutional support: RVO:61388963
Keywords : bacterial carbonic anhydrases * drug discovery * enzymes inhibitors * sulfonamides * Vibrio cholerae
OECD category: Organic chemistry
Impact factor: 3.540, year: 2021
Method of publishing: Open access
https://doi.org/10.1002/cmdc.202100510
Permanent Link: http://hdl.handle.net/11104/0323578 - 7.0540304 - ÚMG 2021 RIV eng U - Conference, Workshop Arrangement
Bartůněk, Petr
11th European Zebrafish Meeting.
[Praha - virtual, 26.10.2020-27.10.2020, (K-WRD 485/475)]
R&D Projects: GA MŠMT LO1419
Institutional support: RVO:68378050
Keywords : Zebrafish * Cell signaling * Chemical Biology * Drug Discovery * Circuits and behavior * Disease Models * Epigenetics * Evolution * Immunity and infection * Metabolism * Morphogenesis and organogenesis * Neurobiology * Patterning * Regeneration * Reproductive biology * Stem Cells * Toxicology
OECD category: Cell biology
https://www.zebrafish2020.org/
Permanent Link: http://hdl.handle.net/11104/0317972 - 8.0540277 - ÚMG 2021 RIV US eng J - Journal Article
Tykvart, J. - Navrátil, V. - Kugler, Michael - Šácha, P. - Schimer, J. - Hlaváčková, A. - Tenora, L. - Zemanová, J. - Dejmek, M. - Král, Vlastimil - Potáček, M. - Majer, P. - Jahn, U. - Brynda, Jiří - Řezáčová, Pavlína - Konvalinka, J.
Identification of Novel Carbonic Anhydrase IX Inhibitors Using High-Throughput Screening of Pooled Compound Libraries by DNA-Linked Inhibitor Antibody Assay (DIANA).
SLAS Discovery. Roč. 25, č. 9 (2020), s. 1026-1037. ISSN 2472-5552. E-ISSN 2472-5560
Institutional support: RVO:68378050
Keywords : high-throughput screening * carbonic anhydrase IX * drug discovery * DNA-linked inhibitor antibody assay
OECD category: Biochemistry and molecular biology
Impact factor: 2.918, year: 2020
Method of publishing: Limited access
https://journals.sagepub.com/doi/10.1177/2472555220918836
Permanent Link: http://hdl.handle.net/11104/0317971 - 9.0539170 - ÚMG 2021 RIV GB eng J - Journal Article
Kugler, Michael - Holub, J. - Brynda, Jiří - Pospíšilová, K. - El Anwar, S. - Bavol, D. - Havránek, M. - Král, Vlastimil - Fábry, Milan - Gruner, B. - Řezáčová, Pavlína
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 35, č. 1 (2020), s. 1800-1810. ISSN 1475-6366. E-ISSN 1475-6374
Institutional support: RVO:68378050
Keywords : tumor hypoxia * medicinal chemistry * drug discovery * binding-sites * inhibition * boron * pharmacophores * opportunities * conjugation * metastasis * Carbonic anhydrase IX * carborane * enzyme inhibitors * structure-activity relationship
OECD category: Biochemistry and molecular biology
Impact factor: 5.051, year: 2020
Method of publishing: Open access
https://www.tandfonline.com/doi/full/10.1080/14756366.2020.1816996
Permanent Link: http://hdl.handle.net/11104/0316870 - 10.0537076 - BC 2021 RIV CH eng J - Journal Article
Aounallah, H. - Bensaoud, Chaima - M'ghirbi, Y. - Faria, F. - Chmelař, J. - Kotsyfakis, Michalis
Tick Salivary Compounds for Targeted Immunomodulatory Therapy.
Frontiers in Immunology. Roč. 11, SEP 23 2020 (2020), č. článku 583845. ISSN 1664-3224. E-ISSN 1664-3224
R&D Projects: GA ČR(CZ) GA19-07247S
Institutional support: RVO:60077344
Keywords : migration inhibitory factor * chemokine-binding protein * ixodes-scapularis * complement inhibitor * sialostatin-l * cell-proliferation * innate immunity * defense system * in-vitro * inflammation * tick saliva * salivary glands * host immunity * immunomodulation * drug discovery
OECD category: Biochemistry and molecular biology
Impact factor: 7.561, year: 2020
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fimmu.2020.583845/full
Permanent Link: http://hdl.handle.net/11104/0314825