Search results
- 1.0472727 - FGÚ 2017 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L. - Silberová, P.
Transgenní potkani převedení do kvality SPF linie SHR/Ola-Tg(Dbh-Dbh)611Ipcv s cDNA genu Dbh (dopamine beta hydroxylase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Line of trangenic rats SHR/Ola-Tg(Dbh-Dbh)611Ipcv with cDNA of Dbh (dopamine beta hydroxylase) gene under control of an endogenous promoter of BN (Brown Norway) strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase, rederived into SPF quality.]
Internal code: SPF SHR/Ola-Tg(Dbh-Dbh)611Ipcv ; 2016
Technical parameters: SPF SHR/Ola-Tg(Dbh-Dbh)611Ipcv. Jedná se o SHR kmen se zvýšenou expresí Dbh transgenu specificky v nadledvině (Pravenec a spol, Physiological Research 65:1039-1044, 2016)
Economic parameters: 20000Kč
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : SPF * transgenic SHR * Dbh (dopamine beta hydroxylase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0269957 - 2.0467648 - FGÚ 2017 RIV CZ eng J - Journal Article
Pravenec, Michal - Landa, Vladimír - Zídek, Václav - Mlejnek, Petr - Šilhavý, Jan - Mir, S.A. - Vaingankar, S. M. - Wang, J. - Kurtz, T. W.
Effects of transgenic expression of dopamine beta hydroxylase (Dbh) gene on blood pressure in spontaneously hypertensive rats.
Physiological Research. Roč. 65, č. 6 (2016), s. 1039-1044. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GAP301/12/0696; GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : spontaneously hypertensive rat * transgenic * dopamine beta hydroxylase * catecholamines * blood pressure * left ventricular mass
Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
Impact factor: 1.461, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265717 - 3.0452393 - FGÚ 2016 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L.
Transgenní potkani linie SHR/Ola-Tg(Dbh-Dbh)611Ipcv s cDNA genu Dbh (dopamine beta hydroxylase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Line of trangenic rats SHR/Ola-Tg(Dbh-Dbh)611Ipcv with cDNA of Dbh (dopamine beta hydroxylase) gene under control of an endogenous promoter of BN (Brown Norway) strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase.]
Internal code: SHR/Ola-Tg(Dbh-Dbh)611Ipcv ; 2015
Technical parameters: Dosud nepublikovaný výsledek. Jedná se o SHR kmen se zvýšenou expresí Dbh transgenu specificky v nadledvině
Economic parameters: Využití pro navazující výzkum a zvýšení objemu výroby
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : transgenic SHR * Dbh (dopamine beta hydroxylase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0253403 - 4.0427128 - FGÚ 2014 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal - Uhlík, L.
Transgenní potkani kmene SHR/Ola s cDNA genu Dbh (dopamine beta hydroxylase) pod kontrolou endogenního promotoru z kmene BN (Brown Norway), získaní pomocí transpozonového vektoru Sleeping Beauty a SB100X hyperaktivní transpozázy.
[Strain of trangenic rats SHR/Ola with cDNA of Dbh (dopamine beta hydroxylase) gene under control of an endogenous promoter of BN (Brown Norway) strain obtained by using the Sleeping Beauty transposon vector and SB100X hyperactive transposase.]
Internal code: SHR/Ola-Tg(Dbh-Dbh) ; 2013
Technical parameters: Dosud nepublikovaný výsledek. Jedná se o SHR kmen se zvýšenou expresí Dbh transgenu specificky v nadledvině
Economic parameters: 20000Kč
R&D Projects: GA TA ČR(CZ) TA02010013
Institutional support: RVO:67985823
Keywords : transgenic SHR * Dbh (dopamine beta hydroxylase) * Sleeping Beauty transposon vector
Subject RIV: EB - Genetics ; Molecular Biology
Permanent Link: http://hdl.handle.net/11104/0232744