Search results
- 1.0571371 - FGÚ 2024 RIV CH eng J - Journal Article
Hüttl, M. - Marková, I. - Miklánková, D. - Zapletalová, I. - Kujal, P. - Šilhavý, Jan - Pravenec, Michal - Malínská, H.
Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model.
Frontiers in Pharmacology. Roč. 14, 3 Apr (2023), č. článku 1117683. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:67985823
Keywords : salsalate * low-grade inflammation * prediabetes * lipid metabolism * cytochrome P450 * oxidative stress
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://doi.org/10.3389/fphar.2023.1117683
Permanent Link: https://hdl.handle.net/11104/0342610File Download Size Commentary Version Access 23_0031_0571371.pdf 0 1.9 MB Publisher’s postprint open-access - 2.0567079 - MBÚ 2024 RIV NL eng J - Journal Article
Kaci, H. - Bodnárová, S. - Fliszar-Nyul, E. - Lemli, B. - Pelantová, Helena - Valentová, Kateřina - Bakos, E. - Ozvegy-Laczka, C. - Poór, M.
Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters.
Biomedicine & Pharmacotherapy. Roč. 157, January 23 (2023), č. článku 114078. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA ČR GA21-00551S
Institutional support: RVO:61388971
Keywords : Luteolin * Naringenin * Sulfate * glucuronide metabolites * Human serum albumin * Cytochrome P450 enzymes * OATP transporters
OECD category: Pharmacology and pharmacy
Impact factor: 7.5, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0753332222014676?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0342645 - 3.0556810 - FGÚ 2023 RIV US eng J - Journal Article
Imig, J. D. - Červenka, L. - Neckář, Jan
Epoxylipids and soluble epoxide hydrolase in heart diseases.
Biochemical Pharmacology. Roč. 195, Jan (2022), č. článku 114866. ISSN 0006-2952. E-ISSN 1873-2968
R&D Projects: GA ČR(CZ) GA18-03207S
Institutional support: RVO:67985823
Keywords : eicosanoids * cytochrome P450 * soluble epoxide hydrolase * hypertension * heart failure * myocardial infarction * inflammation * mitochondrial function * coronary artery
OECD category: Physiology (including cytology)
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bcp.2021.114866
Permanent Link: http://hdl.handle.net/11104/0331112 - 4.0556127 - FGÚ 2023 RIV GB eng J - Journal Article
Riečan, Martin - Palůchová, Veronika - Lopes, Magno - Brejchová, Kristýna - Kuda, Ondřej
Branched and linear fatty acid esters of hydroxy fatty acids (FAHFA) relevant to human health.
Pharmacology and Therapeutics. Roč. 231, Mar (2022), č. článku 107972. ISSN 0163-7258. E-ISSN 1879-016X
R&D Projects: GA MŠMT(CZ) LTAUSA18104
Grant - others:AV ČR(CZ) LQ200111901
Program: Prémie Lumina quaeruntur
Institutional support: RVO:67985823
Keywords : FAHFA * OAHFA * PAHSA * meibum * cytochrome P450 * inhibitors
OECD category: Biochemistry and molecular biology
Impact factor: 13.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.pharmthera.2021.107972
Permanent Link: http://hdl.handle.net/11104/0330479 - 5.0555407 - BFÚ 2022 RIV PL eng J - Journal Article
Krkoška, Martin - Nekvindová, J. - Nevědělová, Kateřina - Zubanova, V. - Radová, L. - Vondráček, Jan - Herudková, Jarmila - Slabý, O. - Kiss, I. - Bohovicova, L. - Fabián, P. - Tylichová, Zuzana - Kala, Z. - Kysela, P. - Ostrizkova, L. - Palička, V. - Vaculová, Alena
Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma.
Pharmacological Reports. Roč. 74, č. 1 (2022), s. 148-158. ISSN 1734-1140. E-ISSN 2299-5684
R&D Projects: GA MZd(CZ) NV17-28231A
Institutional support: RVO:68081707
Keywords : aryl-hydrocarbon receptor * tumor-suppressor * human liver * posttranscriptional regulation * cell-line * cytochrome-p450
OECD category: Pharmacology and pharmacy
Impact factor: 4.4, year: 2022
Method of publishing: Limited access
https://link.springer.com/article/10.1007/s43440-021-00338-9
Permanent Link: http://hdl.handle.net/11104/0329927 - 6.0552845 - ÚEB 2022 RIV GB eng J - Journal Article
Ajduković, J. J. - Jakimov, D. S. - Rárová, L. - Strnad, Miroslav - Dzichenka, Y. U. - Usanov, S. - Škorić, D. - Jovanović-Šanta, S. S. - Sakač, M. N.
Novel alkylaminoethyl derivatives of androstane 3-oximes as anticancer candidates: synthesis and evaluation of cytotoxic effects.
RSC Advances. Roč. 11, č. 59 (2021), s. 37449-37461. E-ISSN 2046-2069
R&D Projects: GA ČR(CZ) GA19-01383S
Institutional support: RVO:61389030
Keywords : HUMAN CYTOCHROME P450(17-ALPHA) * ENDOGENOUS ESTROGEN METABOLITE * STEROIDAL INHIBITORS
OECD category: Organic chemistry
Impact factor: 4.036, year: 2021
Method of publishing: Open access
http://doi.org/10.1039/d1ra07613b
Permanent Link: http://hdl.handle.net/11104/0327941File Download Size Commentary Version Access 2021_Ajdukovic_RSC ADVANCES_37449.pdf 1 910.4 KB Other open-access - 7.0550889 - FGÚ 2022 RIV CH eng J - Journal Article
Hüttl, M. - Marková, I. - Miklánková, D. - Zapletalová, I. - Poruba, M. - Haluzík, M. - Vaněčková, Ivana - Malínská, H.
In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia.
International Journal of Molecular Sciences. Roč. 22, č. 21 (2021), č. článku 11513. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-06199S
Institutional support: RVO:67985823
Keywords : GA19-06199S * empagliflozin * fatty liver * lipid metabolism * cytochrome P450 * fetuin-A * oxidative stress
OECD category: Physiology (including cytology)
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/21/11513
Permanent Link: http://hdl.handle.net/11104/0326199 - 8.0542509 - MBÚ 2022 RIV FR eng J - Journal Article
Faisal, Z. - Mohos, V. - Fliszar-Nyul, E. - Valentová, Kateřina - Káňová, Kristýna - Lemli, B. - Kunsagi-Mate, S. - Poor, M.
Interaction of silymarin components and their sulfate metabolites with human serum albumin and cytochrome P450 (2C9, 2C19, 2D6, and 3A4) enzymes.
Biomedicine & Pharmacotherapy. Roč. 138, JUN 2021 (2021), č. článku 111459. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA ČR(CZ) GA18-00121S
Institutional support: RVO:61388971
Keywords : Silymarin * Sulfate conjugates * Human serum albumin * Cytochrome P450 * Pharmacokinetic interaction * Herb-drug interaction
OECD category: Pharmacology and pharmacy
Impact factor: 7.419, year: 2021
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0753332221002444?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0319906 - 9.0541026 - ÚEB 2022 RIV CZ eng J - Journal Article
Spicakova, A. - Kraus, Petr - Gucký, Tomáš - Kryštof, Vladimír - Strnad, Miroslav - Bazgier, V. - Otyepka, M. - Kubickova, V. - Poruba, M. - Rácová, Z. - Zapletalová, I. - Anzenbacher, P.
in vitro and in silico Studies of Interaction of Synthetic 2,6,9-Trisubstituted Purine Kinase Inhibitors BPA-302, BP-21 and BP-117 With Liver Drug-Metabolizing Cytochromes P450.
Physiological Research. Roč. 69, SEP (2020), s. 627-636. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MZd(CZ) NV17-28231A
Institutional support: RVO:61389030
Keywords : r-roscovitine * cell-cycle * cancer * series * Cytochrome P450 inhibition * High performance liquid chromatography * Cyclin-dependent kinase inhibitor * FLT3-ITD inhibitor * Drug metabolism
OECD category: Organic chemistry
Impact factor: 1.881, year: 2020
Method of publishing: Open access
https://www.biomed.cas.cz/physiolres/pdf/2020/69_S627.pdf
Permanent Link: http://hdl.handle.net/11104/0318600File Download Size Commentary Version Access 2020_Spicakova_Physiological Research_S627.pdf 1 2.5 MB Other open-access - 10.0539733 - ÚMG 2021 RIV CH eng J - Journal Article
Škoda, J. - Dušek, J. - Drastík, M. - Štefela, A. - Dohnalová, Klára - Chalupský, Karel - Smutný, T. - Mičuda, S. - Gerbal-Chaloin, S. - Pávek, P.
Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain.
Cells. Roč. 9, č. 12 (2020), č. článku 2532. E-ISSN 2073-4409
R&D Projects: GA ČR GA19-14497S; GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : diazepam * gene regulation * car * cytochrome P450 * drug interaction
OECD category: Biochemistry and molecular biology
Impact factor: 6.600, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2073-4409/9/12/2532
Permanent Link: http://hdl.handle.net/11104/0317435