Search results
- 1.0583751 - ÚOCHB 2024 CZ eng A - Abstract
Štěpánová, Sille - Gutten, Ondrej - Buděšínský, Miloš - Břehová, Petra - Rulíšek, Lubomír - Kašička, Václav
Acidity constants of cyclic diadenosine diphosphorothioate and its difluorinated derivatives determined by capillary electrophoresis.
9. ročník konference Česká chromatografická škola – HPLC.cz 2023. Program konference/Program sekce plakátových sdělení. Praha: Česká chromatografická škola, 2023. s. 20.
[Česká chromatografická škola – HPLC.cz 2023 /9./. 14.05.2023-17.05.2023, Zaječí]
Institutional support: RVO:61388963
Keywords : acidity constant * capillary electrophoresis * cyclic dinucleotides diphosphorothioates
OECD category: Analytical chemistry
http://ceskachromatografickaskola.cz/admin/Include/Data/getfile.php?id_soubor=64&db=2-ceskachro
Permanent Link: https://hdl.handle.net/11104/0351740File Download Size Commentary Version Access Česká chromatografická škola – HPLC.cz 2023. Program sekce plakátových sdělení.pdf 0 2.2 MB Publisher’s postprint open-access - 2.0583095 - ÚOCHB 2025 RIV US eng J - Journal Article
Štěpánová, Sille - Andris, Erik - Gutten, Ondrej - Buděšínský, Miloš - Dejmek, Milan - Břehová, Petra - Rulíšek, Lubomír - Kašička, Václav
Acidity constants and protonation sites of cyclic dinucleotides determined by capillary electrophoresis, quantum chemical calculations, and NMR spectroscopy.
Electrophoresis. Roč. 45, 7/8 (2024), s. 687-705. ISSN 0173-0835. E-ISSN 1522-2683
Institutional support: RVO:61388963
Keywords : acidity constant * capillary electrophoresis * cyclic dinucleotides * DFT calculations * NMR spectroscopy
Impact factor: 2.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/elps.202300232
Permanent Link: https://hdl.handle.net/11104/0351092 - 3.0582968 - ÚOCHB 2024 RIV CZ eng A - Abstract
Pimková Polidarová, Markéta - Dejmek, Milan - Hirsch, Ivan - Brázdová, Andrea - Grantz Šašková, Klára
STING agonist-induced CD14+ monocyte depletion involves multiple regulated cell death mechanisms.
Czech Chemical Society Symposium Series. Roč. 21, č. 2 (2023), s. 104. ISSN 2336-7202.
[Interdisciplinary meeting of young life scientists /22./. 15.05.2023-18.05.2023, Milovy]
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : STING * cyclic dinucleotides * CD14 monocytes * regulated cell death
OECD category: Cell biology
http://www.ccsss.cz/index.php/ccsss/issue/view/38
Permanent Link: https://hdl.handle.net/11104/0351004 - 4.0581779 - ÚOCHB 2025 RIV US eng J - Journal Article
Štěpánová, Sille - Břehová, Petra - Kašička, Václav
The separation of cyclic diadenosine diphosphorothioate and the diastereomers of its difluorinated derivative and the estimation of the binding constants and ionic mobilities of their complexes with 2-hydroxypropyl-β-cyclodextrin by affinity capillary electrophoresis.
Electrophoresis. (2024). ISSN 0173-0835. E-ISSN 1522-2683
R&D Projects: GA ČR(CZ) GA20-03899S
Institutional support: RVO:61388963
Keywords : affinity capillary electrophoresis * binding constant * chiral analysis * cyclic dinucleotides * cyclodextrins
Impact factor: 2.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/elps.202300191
Permanent Link: https://hdl.handle.net/11104/0349913 - 5.0574383 - ÚOCHB 2024 RIV NL eng J - Journal Article
Dejmek, Milan - Brázdová, Andrea - Otava, Tomáš - Pimková Polidarová, Markéta - Klíma, Martin - Smola, Miroslav - Vavřina, Zdeněk - Buděšínský, Miloš - Dračínský, Martin - Liboska, Radek - Bouřa, Evžen - Birkuš, Gabriel - Nencka, Radim
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy.
European Journal of Medicinal Chemistry. Roč. 259, November (2023), č. článku 115685. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LX22NPO5103; GA MZd(CZ) NU20-05-00472
Research Infrastructure: CCP II - 90126
Institutional support: RVO:61388963
Keywords : cyclic dinucleotides * STING * cancer * intratumoral administration * immunotherapy
OECD category: Medicinal chemistry
Impact factor: 6.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2023.115685
Permanent Link: https://hdl.handle.net/11104/0344716File Download Size Commentary Version Access 10.1016j.ejmech.2023.115685.pdf 0 5.2 MB Publisher’s postprint open-access
Research data: PDB - 6.0565752 - ÚOCHB 2024 RIV DE eng J - Journal Article
Magand, J. - Roy, V. - Meudal, H. - Rose, S. - Quesniaux, V. - Chalupská, Dominika - Agrofoglio, L. A.
Synthesis of Novel 3’,3’-cyclic Dinucleotide Analogues Targeting STING Protein.
Asian Journal of Organic Chemistry. Roč. 12, č. 1 (2023), č. článku e202200597. ISSN 2193-5807. E-ISSN 2193-5815
Institutional support: RVO:61388963
Keywords : CuAAC * 3’,3’-cyclic dinucleotides * macrocyclization * ring-closing metathesis * STING protein * 1,2,3-triazole
OECD category: Organic chemistry
Impact factor: 2.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/ajoc.202200597
Permanent Link: https://hdl.handle.net/11104/0337260 - 7.0559980 - ÚOCHB 2023 RIV GB eng J - Journal Article
Dejmek, Milan - Šála, Michal - Brázdová, Andrea - Vaneková, Lenka - Smola, Miroslav - Klíma, Martin - Břehová, Petra - Buděšínský, Miloš - Dračínský, Martin - Procházková, Eliška - Zavřel, Martin - Šimák, Ondřej - Páv, Ondřej - Bouřa, Evžen - Birkuš, Gabriel - Nencka, Radim
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential.
Structure. Roč. 30, č. 8 (2022), s. 1146-1156. ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : cyclic dinucleotides * prodrugs * STING agonists * isonucleosides * cytokines * cancer
OECD category: Organic chemistry
Impact factor: 5.7, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.str.2022.05.012
Permanent Link: https://hdl.handle.net/11104/0333087 - 8.0545469 - ÚOCHB 2022 RIV DE eng J - Journal Article
Hejdánková, Zuzana - Vaněk, Václav - Sedlák, František - Procházka, Jan - Diederichs, Audrey - Kereiche, Sami - Novotná, Barbora - Buděšínský, Miloš - Birkuš, Gabriel - Grantz Šašková, Klára - Cígler, Petr
Lipid Nanoparticles for Broad-Spectrum Nucleic Acid Delivery.
Advanced Functional Materials. Roč. 31, č. 47 (2021), č. článku 2101391. ISSN 1616-301X. E-ISSN 1616-3028
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : cyclic dinucleotides * DNA * drug delivery * lipid nanoparticles * RNA
OECD category: Biochemistry and molecular biology
Impact factor: 19.924, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/adfm.202101391
Permanent Link: http://hdl.handle.net/11104/0322155 - 9.0541558 - ÚOCHB 2022 RIV DE eng J - Journal Article
Smola, Miroslav - Gutten, Ondrej - Dejmek, Milan - Kožíšek, Milan - Evangelidis, Thomas - Tehrani, Zahra Aliakbar - Novotná, Barbora - Nencka, Radim - Birkuš, Gabriel - Rulíšek, Lubomír - Bouřa, Evžen
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angewandte Chemie - International Edition. Roč. 60, č. 18 (2021), s. 10172-10178. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GA20-08772S; GA MŠMT(CZ) EF16_019/0000729
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963
Keywords : conformational analysis * cyclic dinucleotides * entropy * quantum chemistry * strain energy
OECD category: Physical chemistry
Impact factor: 16.823, year: 2021
Method of publishing: Open access
https://doi.org/10.1002/anie.202016805
Permanent Link: http://hdl.handle.net/11104/0319101