Search results
- 1.0489934 - ÚOCHB 2019 RIV US eng J - Journal Article
Hánová, Iva - Brynda, Jiří - Houštecká, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Marešová, Lucie - Vondrášek, Jiří - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Cell Chemical Biology. Roč. 25, č. 3 (2018), s. 318-329. ISSN 2451-9448. E-ISSN 2451-9448
R&D Projects: GA ČR GA15-18929S; GA ČR GA13-11043S; GA MŠMT LO1302; GA ČR GA14-33693S
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : cathepsin D * activation intermediate * crystal structure
OECD category: Biochemistry and molecular biology
Impact factor: 6.762, year: 2018
https://www.sciencedirect.com/science/article/pii/S2451945618300011?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0284232 - 2.0487070 - ÚOCHB 2018 CA eng A - Abstract
Hobizalová, Radka - Palová, Lenka - Fanfrlík, Jindřich - Brynda, Jiří - Monincová, Lenka - Lepšík, Martin - Horn, Martin - Majer, Pavel - Mareš, Michael
Novel macrocyclic inhibitors of human cathepsin D.
IPS 2017. 10th General Meeting of the International Proteolysis Society. Banff: International Proteolysis Society, 2017. s. 150.
[IPS 2017. General Meeting of the International Proteolysis Society /10./. 28.10.2017-02.11.2017, Banff]
R&D Projects: GA ČR GA15-18929S; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : human cathepsin D * inhibitors
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0281750 - 3.0471803 - ÚOCHB 2017 RIV GB eng J - Journal Article
Sojka, D. - Hartmann, D. - Bartošová-Sojková, P. - Dvořák, Jan
Parasite Cathepsin D-Like Peptidases and Their Relevance as Therapeutic Targets.
Trends in Parasitology. Roč. 32, č. 9 (2016), s. 708-723. ISSN 1471-4922. E-ISSN 1471-5007
R&D Projects: GA ČR GA13-11043S; GA ČR(CZ) GAP302/11/1481
Institutional support: RVO:61388963
Keywords : aspartic peptidases * cathepsin D * hemoglobinolysis * parasites * vectors
Subject RIV: CE - Biochemistry
Impact factor: 6.333, year: 2016
Permanent Link: http://hdl.handle.net/11104/0269132 - 4.0471335 - ÚOCHB 2017 IT eng A - Abstract
Hánová, Iva - Brynda, Jiří - Hobizalová, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Structural mechanism of regulation of aspartic proteases through a propeptide-binding exosite: a lesson from blood feeding parasites.
Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors. Barga: GRC, 2016.
[Gordon Research Conference on Proteolytic Enzymes & Their Inhibitors. 26.06.2016-01.07.2016, Barga]
R&D Projects: GA ČR GA15-18929S; GA ČR GA13-11043S; GA MŠMT LO1302
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : cathepsin D * exosite * inhibitor
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0268799 - 5.0471239 - ÚOCHB 2017 CZ eng A - Abstract
Monincová, Lenka - Pallová, Lenka - Hobizalová, Radka - Mareš, Michael - Majer, Pavel
Design, synthesis and activity of novel macrocyclic inhibitors of human cathepsin D.
Liblice 2016. 51st Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2016. s. 114.
[Liblice 2016. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /51./. 11.11.2016-13.11.2016, Lázně Bělohrad]
Institutional support: RVO:61388963
Keywords : cathepsin D * macrocyclic inhibitors
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0268789 - 6.0463316 - BC 2017 RIV GB eng J - Journal Article
Sojka, Daniel - Hartmann, David - Bartošová-Sojková, Pavla - Dvořák, Jan
Parasite Cathepsin D-Like Peptidases and Their Relevance as Therapeutic Targets.
Trends in Parasitology. Roč. 32, č. 9 (2016), s. 708-723. ISSN 1471-4922. E-ISSN 1471-5007
R&D Projects: GA ČR GA14-33693S; GA ČR GA13-11043S; GA ČR(CZ) GAP302/11/1481
EU Projects: European Commission(XE) 248642 - SCHISTOSOMA PROTEASE
Institutional support: RVO:60077344 ; RVO:68378050
Keywords : aspartic peptidases * cathepsin D * hemoglobinolysis * parasites * vectors
Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine
Impact factor: 6.333, year: 2016
Permanent Link: http://hdl.handle.net/11104/0262535 - 7.0459968 - ÚOCHB 2017 CZ eng A - Abstract
Hánová, Iva - Brynda, Jiří - Hobizalová, Radka - Alam, N. - Sojka, Daniel - Kopáček, Petr - Marešová, Lucie - Vondrášek, Jiří - Horn, Martin - Schueler-Furman, O. - Mareš, Michael
Structural mechanism of regulation of aspartic proteases through a propeptide-binding exosite: a lesson from blood-feeding parasites.
Prague Protein Spring Meeting 2016: Proteins and their Design. Praha: Ústav organické chemie a biochemie AV ČR, 2016. s. 71. ISBN 978-80-86241-55-5.
[Prague Protein Spring Meeting 2016: Proteins and their Design /4./. 05.05.2016-08.05.2016, Praha]
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : cathepsin D * aspartic proteases
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0260115 - 8.0455772 - ÚOCHB 2016 RIV US eng J - Journal Article
Guo, J. - Erskine, P. T. - Coker, A. R. - Wood, S. P. - Cooper, J. B. - Mareš, Michael - Baudyš, Miroslav
Structure of a Kunitz-type potato cathepsin D inhibitor.
Journal of Structural Biology. Roč. 192, č. 3 (2015), s. 554-560. ISSN 1047-8477. E-ISSN 1095-8657
R&D Projects: GA ČR GA15-18929S; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : potato cathepsin D inhibitor * Kunitz-type protease inhibitor * protein X-ray structure * reactive-site loop * docking
Subject RIV: CE - Biochemistry
Impact factor: 2.570, year: 2015
Permanent Link: http://hdl.handle.net/11104/0256395 - 9.0443510 - ÚOCHB 2016 CZ eng A - Abstract
Srp, Jaroslav - Pachl, Petr - Řezáčová, Pavlína - Vondrášek, Jiří - Nussbaumerová, Martina - Horn, Martin - Mareš, Michael
A plant-insect interaction in 3D.
Materials Structure in Chemistry, Biology, Physics and Technology. Czech and Slovak Crystallographic Association. Roč. 22, č. 1 (2015), s. 55. ISSN 1211-5894.
[Discussions in Structural Molecular Biology. Annual Meeting of the Czech Society for Structural Biology /13./. 19.03.2015-21.03.2015, Nové Hrady]
Institutional support: RVO:61388963
Keywords : LdCD * potato cathepsin D inhibitor * crystal structure
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0246311 - 10.0425068 - ÚOCHB 2014 RIV GB eng M - Monography Chapter
Fusek, M. - Mareš, Michael - Větvička, V.
Cathepsin D.
Handbook of Proteolytic Enzymes. Amsterdam: Academic Press, 2013 - (Rawlings, N.; Salvesen, G.), s. 54-63. ISBN 978-0-12-382219-2
R&D Projects: GA AV ČR IAA400550705
Institutional support: RVO:61388963
Keywords : cathepsin D * protease * aspartic peptidase * apoptosis * cancer
Subject RIV: CE - Biochemistry
Permanent Link: http://hdl.handle.net/11104/0231014