Search results
- 1.0561407 - ÚMCH 2023 RIV US eng J - Journal Article
Pechar, Michal - Pola, Robert - Studenovský, Martin - Bláhová, Markéta - Grosmanová, Eliška - Dydowiczová, Aneta - Filipová, Marcela - Islam, R. - Gao, S. - Fang, J. - Etrych, Tomáš
Polymer nanomedicines with enzymatically triggered activation: a comparative study of in vitro and in vivo anti-cancer efficacy related to the spacer structure.
Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 46, November (2022), č. článku 102597. ISSN 1549-9634. E-ISSN 1549-9642
R&D Projects: GA ČR(CZ) GA22-12483S; GA MŠMT(CZ) LTAUSA18083
Grant - others:AV ČR(CZ) JSPS-22-01
Program: Bilaterální spolupráce
Institutional support: RVO:61389013
Keywords : drug delivery * polymer cancerostatics * enzymatic release
OECD category: Polymer science
Impact factor: 5.4, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S1549963422000831
Permanent Link: https://hdl.handle.net/11104/0334099 - 2.0542621 - MBÚ 2022 RIV CH eng J - Journal Article
Gorniakova, D. - Petříček, M. - Kahoun, D. - Grabic, R. - Zelenka, Tomáš - Chroňáková, Alica - Petříčková, K.
Activation of a Cryptic Manumycin-Type Biosynthetic Gene Cluster of Saccharothrix espanaensis DSM44229 by Series of Genetic Manipulations.
Microorganisms. Roč. 9, č. 3 (2021), č. článku 559. E-ISSN 2076-2607
R&D Projects: GA MZd(CZ) NV17-30091A
Institutional support: RVO:61388971 ; RVO:60077344
Keywords : manumycin * colabomycin * cryptic BGC activation * actinomycetes * Saccharothrix * secondary metabolites * immunomodulators * cancerostatics
OECD category: Microbiology; Microbiology (BC-A)
Impact factor: 4.926, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-2607/9/3/559
Permanent Link: http://hdl.handle.net/11104/0320016 - 3.0499714 - ÚMCH 2020 RIV US eng J - Journal Article
Pola, Robert - Král, Vlastimil - Filippov, Sergey K. - Kaberov, Leonid I. - Etrych, Tomáš - Sieglová, Irena - Sedláček, Juraj - Fábry, Milan - Pechar, Michal
Polymer cancerostatics targeted by recombinant antibody fragments to GD2-positive tumor cells.
Biomacromolecules. Roč. 20, č. 1 (2019), s. 412-421. ISSN 1525-7797. E-ISSN 1526-4602
R&D Projects: GA ČR(CZ) GA16-17207S; GA MZd(CZ) NV16-28594A; GA MPO FV10312
Institutional support: RVO:61389013 ; RVO:68378050
Keywords : polymer cancerostatics * drug targeting * scFv
OECD category: Polymer science; Biochemical research methods (UMG-J)
Impact factor: 6.092, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.biomac.8b01616
Permanent Link: http://hdl.handle.net/11104/0292360 - 4.0475046 - ÚMCH 2018 US eng A - Abstract
Pechar, Michal - Pola, Robert - Janoušková, Olga - Sieglová, Irena - Král, Vlastimil - Fábry, Milan - Tomalová, Barbora - Kovář, Marek
Polymer cancerostatics with a coiled coil motif targeted against murine leukemia.
Journal of Pharmaceutics & Drug Delivery Research. Roč. 6, 4 (Suppl) (2017), s. 36. ISSN 2325-9604.
[International Conference and Exhibition on Nanomedicine and Drug Delivery. 29.05.2017-31.05.2017, Osaka]
R&D Projects: GA ČR(CZ) GA16-17207S
Institutional support: RVO:61389013 ; RVO:68378050 ; RVO:61388971
Keywords : coiled coil * polymer cancerostatics * active targeting
Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M)
https://www.scitechnol.com/conference-abstracts/scientific-tracks-abstracts/nanodelivery-2017-proceedings.html
Permanent Link: http://hdl.handle.net/11104/0272212 - 5.0460189 - ÚMCH 2017 SK eng A - Abstract
Pechar, Michal - Pola, Robert - Janoušková, Olga - Sieglová, Irena - Král, Vlastimil - Fábry, Milan - Tomalová, Barbora - Kovář, Marek
Actively targeted polymer cancerostatics with a coiled coil motif: in vivo evaluation.
Program a Zborník príspevkov. Bratislava: Ústav polymérov SAV, 2016. s. 21-22. ISBN 978-80-89841-00-4.
[Slovensko-Česká konferencia Polyméry 2016 /9./. 08.06.2016-10.06.2016, Stará Lesná]
R&D Projects: GA ČR(CZ) GA16-17207S
Institutional support: RVO:61389013 ; RVO:68378050 ; RVO:61388971
Keywords : coiled coil * polymer cancerostatics * active targeting
Subject RIV: CD - Macromolecular Chemistry; EB - Genetics ; Molecular Biology (UMG-J); FD - Oncology ; Hematology (MBU-M)
Permanent Link: http://hdl.handle.net/11104/0260325 - 6.0369686 - ÚMCH 2012 US eng P - Patent Document
Ulbrich, Karel - Etrych, Tomáš - Říhová, Blanka - Jelínková, Markéta - Kovář, Marek
pH-sensitive polymeric conjugates of an anthracycline cancerostatic drug for targeted therapy.
Alexandria: United States Patent and Trademark Office, 2011. Owner: Zentiva, k. s. Date of the patent acceptance: 05.04.2011. Patent Number: US7919076
Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z50200510
Keywords : cancerostatics * polymer cojugates * targeted therapy
Subject RIV: CC - Organic Chemistry
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=7919076&OS=7919076&RS=7919076
Permanent Link: http://hdl.handle.net/11104/0203694 - 7.0339530 - ÚMCH 2010 RU rus P - Patent Document
Ulbrich, Karel - Etrych, Tomáš - Říhová, Blanka - Jelínková, Markéta - Kovář, Marek
pH-chuvstvitel'nye polimernye kon'jugaty antraciklinovyh kancerostaticheskih aktivnyh agentov dlja terapii napravlennogo dejstvija.
[pH sensitive polymer conjugates of anthracycline cancerostatic for targeted therapy.]
Moskva: Euroasijská patentní organizace, 2006. Owner: Zentiva. Date of the patent registration: 12.02.2002. Date of the patent acceptance: 27.10.2006. Patent Number: 007353
Institutional research plan: CEZ:AV0Z4050913
Keywords : cancerostatics * polymer cojugates * targeted therapy
Subject RIV: CD - Macromolecular Chemistry
Permanent Link: http://hdl.handle.net/11104/0183033 - 8.0338868 - ÚMCH 2010 RIV DE eng, ger, fre P - Patent Document
Ulbrich, Karel - Etrych, Tomáš - Říhová, Blanka - Jelínková, Markéta - Kovář, Marek
pH-sensitive polymeric conjugates of an anthracycline cancerostatic drug for targeted therapy.
Munich: European Patent Office, 2009. Owner: Zentiva. Date of the patent registration: 20.12.2002. Date of the patent acceptance: 19.08.2009. Patent Number: EP 1 463 529 B1
R&D Projects: GA AV ČR KSK4055109
Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z50200510
Keywords : cancerostatics * polymer cojugates * targeted therapy
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0182529 - 9.0321935 - ÚMCH 2009 RIV CZ cze J - Journal Article
Pechar, Michal - Ulbrich, Karel
Polymerní terapeutika u nás a ve světě.
[Polymer Therapeutics.]
Chemické listy. Roč. 103, č. 1 (2009), s. 3-10. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA AV ČR KAN200200651; GA MŠMT 1M0505
EU Projects: European Commission(XE) 512087 - GIANT
Institutional research plan: CEZ:AV0Z40500505
Keywords : polymer drug * hydrophylic polymers * cancerostatics
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 0.717, year: 2009
Permanent Link: http://hdl.handle.net/11104/0170331 - 10.0188686 - UMCH-V 20023297 CZ cze A - Abstract
Etrych, Tomáš - Strohalm, Jiří - Plocová, Daniela - Jelínková, Markéta - Kovář, Marek - Říhová, Blanka - Ulbrich, Karel
Polymerní konjugáty protirakovinných léčiv směrovaných protilátkami.
[Antibody-targetted polymer conjugates of cancerostatics.]
80-85009-45-5. Polymery 2002. Praha: Ústav makromolekulární chemie AV ČR, 2002 - (Kahovec, J.). s. KS09
[Česko-slovenská konference Polymery 2002. 16.09.2002-17.09.2002, Praha]
R&D Projects: GA ČR GA305/02/1425
Keywords : polymer conjugates * cancerostatics
Subject RIV: FD - Oncology ; Hematology
Permanent Link: http://hdl.handle.net/11104/0084596