Search results
- 1.0584241 - ÚEM 2025 RIV NL eng J - Journal Article
Mezeiová, E. - Prchal, L. - Hrabinová, M. - Mucková, L. - Pulkrabková, L. - Soukup, O. - Misiachna, Anna - Janoušek, J. - Fibigar, J. - Kučera, T. - Horák, Martin - Makhaeva, G.F. - Korabecný, J.
Morphing cholinesterase inhibitor amiridine into multipotent drugs for the
treatment of Alzheimer’s disease.
Biomedicine & Pharmacotherapy. Roč. 173, april. (2024), č. článku 116399. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA ČR(CZ) GA22-24384S; GA MŠMT(CZ) EH22_008/0004562
Institutional support: RVO:68378041
Keywords : amiridine * acetylcholinesterase * antioxidant capacity * butyrylcholinesterase * multi-target directed ligands * NMDA receptors
OECD category: Neurosciences (including psychophysiology
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S075333222400283X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0352201File Download Size Commentary Version Access Mezeirová 2024.pdf 1 1.7 MB Author´s preprint open-access - 2.0570474 - ÚEB 2024 RIV GB eng J - Journal Article
Gonzalez, G. - Kvasnica, Miroslav - Svrčková, K. - Štěpánková, Š. - Santos, J. R. C. - Peřina, M. - Jorda, R. - Lopes, S. M.M. - Melo, T.
Ring-fused 3 beta-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 225, JAN (2023), č. článku 106194. ISSN 0960-0760
R&D Projects: GA ČR GA20-15621S
Institutional support: RVO:61389030
Keywords : Neuroprotective agents * Cholinesterase inhibitors * Acetylcholinesterase and butyrylcholinesterase * enzymes * Hexacyclic steroids * SteroidalN-sulfonyl-1-azadiene
OECD category: Biochemistry and molecular biology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.jsbmb.2022.106194
Permanent Link: https://hdl.handle.net/11104/0341775File Download Size Commentary Version Access 2023_Gonzalez_JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY_106194.pdf 1 5.7 MB Other open-access - 3.0543720 - ÚVGZ 2022 RIV CH eng J - Journal Article
Kos, J. - Strharsky, T. - Štěpánková, Š. - Svrčková, K. - Oravec, Michal - Hošek, J. - Imramovský, A. - Jampílek, J.
Trimethoxycinnamates and Their Cholinesterase Inhibitory Activity.
Applied Sciences-Basel. Roč. 11, č. 10 (2021), č. článku 4691. E-ISSN 2076-3417
R&D Projects: GA MŠMT(CZ) EF16_019/0000797; GA MŠMT(CZ) LM2015061
Research Infrastructure: CzeCOS III - 90123
Institutional support: RVO:86652079
Keywords : biological evaluation * 3,4,5-trimethoxycinnamic acid * butyrylcholinesterase * acetylcholinesterase * derivatives * design * discovery * analogs * hybrids * trimethoxycinnamates * cholinesterase-inhibiting activity * cytotoxicity * structure-activity relationships
OECD category: Organic chemistry
Impact factor: 2.838, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3417/11/10/4691
Permanent Link: http://hdl.handle.net/11104/0320889 - 4.0541833 - ÚEM 2022 RIV CH eng J - Journal Article
Konečný, J. - Misiachna, Anna - Hrabinová, M. - Pulkrábková, L. - Benková, M. - Prchal, L. - Kučera, T. - Kobrlová, T. - Finger, V. - Kolcheva, Marharyta - Kortus, Štěpán - Jun, D. - Valko, M. - Horák, Martin - Soukup, O. - Korábečný, J.
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Biomolecules. Roč. 11, č. 1 (2021), č. článku 3. E-ISSN 2218-273X
R&D Projects: GA MZd(CZ) NU20-08-00296
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:68378041
Keywords : acetylcholinesterase * Alzheimer´s disease * butyrylcholinesterase * fluorene * in vitro * in silico * multi-target directed ligands * N-methyl-d-aspartate receptor
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/1/3
Permanent Link: http://hdl.handle.net/11104/0319349 - 5.0541685 - FGÚ 2022 RIV CH eng J - Journal Article
Konečný, J. - Misiachna, Anna - Hrabinová, M. - Pulkrábková, L. - Benková, M. - Prchal, L. - Kučera, T. - Kobrlová, T. - Finger, V. - Kolcheva, Marharyta - Kortus, Štěpán - Jun, D. - Valko, M. - Horák, Martin - Soukup, O. - Korábečný, J.
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Biomolecules. Roč. 11, č. 1 (2021), č. článku 3. E-ISSN 2218-273X
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:67985823
Keywords : acetylcholinesterase * Alzheimer´s disease * butyrylcholinesterase * fluorene * in vitro * in silico * multi-target directed ligands * N-methyl-d-aspartate receptor
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/1/3
Permanent Link: http://hdl.handle.net/11104/0319216 - 6.0524494 - ÚVGZ 2021 RIV CH eng J - Journal Article
Hudcová, A. - Kroutil, A. - Kubínová, R. - Garro, A. D. - Gutierrez, L. J. - Enriz, D. - Oravec, Michal - Csöllei, J.
Arylaminopropanone derivatives as potential cholinesterase inhibitors: Synthesis, docking study and biological evaluation.
Molecules. Roč. 25, č. 7 (2020), č. článku molecules25071751. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) LM2018123
Research Infrastructure: CzeCOS III - 90123
Institutional support: RVO:86652079
Keywords : Acetylcholinesterase * Arylaminopropanone * Butyrylcholinesterase * Enzyme assays * Molecular modelling * N-phenylcarbamate
OECD category: Pharmacology and pharmacy
Impact factor: 4.412, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1420-3049/25/7/1751
Permanent Link: http://hdl.handle.net/11104/0308848 - 7.0501560 - ÚOCHB 2020 RIV ZA eng J - Journal Article
Kubínová, R. - Gazdová, M. - Hanáková, Z. - Jurkaninová, S. - Dall'Acqua, S. - Cvačka, Josef - Humpa, O.
New diterpenoid glucoside and flavonoids from Plectranthus scutellarioides (L.) R. Br.
South African Journal of Botany. Roč. 120, Jan (2019), s. 286-290. ISSN 0254-6299. E-ISSN 1727-9321
Institutional support: RVO:61388963
Keywords : Plectranthus scutellarioides * diterpene glucoside * flavonoids * hyaluronidase * ORAC values * acetylcholinesterase and butyrylcholinesterase * inhibitory activities
OECD category: Pharmacology and pharmacy
Impact factor: 1.792, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0254629918308366?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0296366 - 8.0483037 - ÚVGZ 2019 RIV CH eng J - Journal Article
Padrtova, T. - Marvanová, P. - Odehnalová, K. - Kubínová, R. - Parravicini, V. - Garro, A. - Enriz, R. D. - Humpa, O. - Oravec, Michal - Mokrý, P.
Synthesis, analysis, cholinesterase-inhibiting activity and molecular modelling studies of 3-(dialkylamino)-2-hydroxypropyl 4-[(alkoxy-carbonyl)amino]benzoates and their quaternary ammonium salts.
Molecules. Roč. 22, č. 12 (2017), č. článku 2048. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) LM2015061; GA MŠMT(CZ) LO1415; GA MŠMT(CZ) EF16_013/0001609
Research Infrastructure: CzeCOS II - 90061
Institutional support: RVO:86652079
Keywords : Acetylcholinesterase * Arylcarbonyloxyaminopropanols * Butyrylcholinesterase * Quaternary ammonium salts * Tertiary amines
OECD category: Biochemistry and molecular biology
Impact factor: 3.098, year: 2017
Permanent Link: http://hdl.handle.net/11104/0278463 - 9.0459172 - ÚOCHB 2017 RIV GB eng J - Journal Article
Pejchal, V. - Štěpánková, Š. - Pejchalová, M. - Královec, K. - Havelek, R. - Růžičková, Z. - Ajani, Haresh - Lo, Rabindranath - Lepšík, Martin
Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors.
Bioorganic & Medicinal Chemistry. Roč. 24, č. 7 (2016), s. 1560-1572. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA ČR GBP208/12/G016
Institutional support: RVO:61388963
Keywords : halogenated benzothiazole * carbamates * acetylcholinesterase * butyrylcholinesterase inhibition * pseudo-irreversible mechanism * covalent docking
Subject RIV: CC - Organic Chemistry
Impact factor: 2.930, year: 2016
Permanent Link: http://hdl.handle.net/11104/0259410 - 10.0384913 - ÚOCHB 2013 RIV US eng J - Journal Article
Novák, Z. - Chlebek, J. - Opletal, L. - Jiroš, Pavel - Macáková, K. - Kuneš, J. - Cahlíková, L.
Corylucinine, a new Alkaloid from Corydalis cava (Fumariaceae), and its Cholinesterase Activity.
Natural Product Communications. Roč. 7, č. 7 (2012), s. 859-860. ISSN 1934-578X. E-ISSN 1555-9475
Grant - others:SVV UK(CZ) 265002; SVV UK(CZ) 265001; FRVŠ(CZ) 664/2011; UNCE UK(CZ) 17/2012/
Institutional research plan: CEZ:AV0Z40550506
Keywords : Corydalis cava * corylucinine * 8-trichloromethyl-7,8-dihydropalmatine * acetylcholinesterase * butyrylcholinesterase * Alzheimer's disease
Subject RIV: CC - Organic Chemistry
Impact factor: 0.956, year: 2012
Permanent Link: http://hdl.handle.net/11104/0214376