Search results
- 1.0583649 - ÚCHP 2025 RIV US eng J - Journal Article
Hamala, Vojtěch - Ondrášková, K. - Červenková Šťastná, Lucie - Krčil, Aleš - Müllerová, Monika - Kurfiřt, Martin - Hiršová, Kateřina - Holčáková, J. - Gyepes, R. - Císařová, I. - Bernášková, Jana - Hrstka, R. - Karban, Jindřich
Improving the anticancer activity of fluorinated glucosamine and galactosamine analogs by attachment of a ferrocene or ruthenium tetrazene motif.
Applied Organometallic Chemistry. Roč. 38, č. 5 (2024), č. článku e7399. ISSN 0268-2605. E-ISSN 1099-0739
R&D Projects: GA MŠMT(CZ) LTC20052
Grant - others:MEYS(XE) CA18103
Institutional support: RVO:67985858
Keywords : antitumor * cytotoxicity * ferrocene * apoptosis
OECD category: Inorganic and nuclear chemistry
Impact factor: 3.9, year: 2022
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1002/aoc.7399
Permanent Link: https://hdl.handle.net/11104/0351673File Download Size Commentary Version Access Applied Organom Chemis - 2024 - Hamala - Improving the anticancer activity of fluorinated glucosamine and galactosamine-1.pdf 0 1.8 MB Publisher’s postprint open-access - 2.0574490 - BC 2024 RIV NL eng J - Journal Article
Penjarla, S. - Reddy, P.Y. - Penta, S. - Sanghvi, Y.S. - Eyer, Luděk - Štefánik, M. - Růžek, Daniel - Banerjee, S.
Efficient synthesis of novel 2-deoxy-C-nucleosides containing oxa and thiadiazole derivatives and their biological activity.
Journal of Molecular Structure. Roč. 1292, NOV (2023), č. článku 136099. ISSN 0022-2860. E-ISSN 1872-8014
R&D Projects: GA MŠMT(CZ) LTAUSA18016
Institutional support: RVO:60077344
Keywords : Cnucleoside * Oxadiazoles * Thiadiazoles * Antiviral * Antitumor * Heterocycles
OECD category: Microbiology
Impact factor: 3.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0022286023011924?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0345916 - 3.0561802 - FZÚ 2024 RIV NL eng J - Journal Article
Garberová, M. - Potočňák, I. - Tvrdoňová, M. - Bago-Pilátová, M. - Bekešová, S. - Kudličková, A. - Samoľová, Erika - Kešeľáková, A. - Elečko, J. - Vilková, M.
Spectral, structural, and pharmacological studies of perillaldehyde and myrtenal based benzohydrazides.
Journal of Molecular Structure. Roč. 1271, Jan (2023), č. článku 134112. ISSN 0022-2860. E-ISSN 1872-8014
Institutional support: RVO:68378271
Keywords : hydrazone * 1H, 13C, and 15N NMR * X-ray analysis * HR-MS * antitumor activity
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 3.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.molstruc.2022.134112
Permanent Link: https://hdl.handle.net/11104/0341680 - 4.0560992 - ÚOCHB 2023 RIV US eng J - Journal Article
Santos, L. H. - Kronenberger, T. - Almeida, R. G. - Silva, E. B. - Rocha, R. E. O. - Oliveira, J. C. - Barreto, L. V. - Skinner, D. - Fajtová, Pavla - Giardini, M. A. - Woodworth, B. - Bardine, C. - Lourenço, A. L. - Craik, C. S. - Poso, A. - Podust, L. M. - McKerrow, J. H. - Siqueira-Neto, J. L. - O'Donoghue, A. J. - Da Silva Júnior, E. N. - Ferreira, R. S.
Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2.
Journal of Chemical Information and Modeling. Roč. 62, č. 24 (2022), s. 6553-6573. ISSN 1549-9596. E-ISSN 1549-960X
Institutional support: RVO:61388963
Keywords : nor-β-lapachone * Trypanosoma cruzi activity * potent antitumor activity
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acs.jcim.2c00693
Permanent Link: https://hdl.handle.net/11104/0333755 - 5.0560039 - BFÚ 2023 RIV US eng J - Journal Article
Hreusová, Monika - Novohradský, Vojtěch - Marková, Lenka - Kostrhunová, Hana - Potočňák, I. - Brabec, Viktor - Kašpárková, Jana
Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells.
Bioinorganic Chemistry and Applications. Roč. 2022, APR 23 2022 (2022), č. článku 3095749. ISSN 1565-3633. E-ISSN 1687-479X
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : TRIS(8-QUINOLINOLATO)GALLIUM(III) * THIOSEMICARBAZONES * POLYPHARMACOLOGY * ANTITUMOR * KP46
OECD category: Biochemistry and molecular biology
Impact factor: 3.8, year: 2022
Method of publishing: Open access
https://www.hindawi.com/journals/bca/2022/3095749/
Permanent Link: https://hdl.handle.net/11104/0340536 - 6.0554462 - BFÚ 2022 RIV CH eng J - Journal Article
Hreusová, Monika - Brabec, Viktor - Nováková, Olga
Processing and Bypass of a Site-Specific DNA Adduct of the Cytotoxic Platinum-Acridinylthiourea Conjugate by Polymerases Involved in DNA Repair: Biochemical and Thermodynamic Aspects.
International Journal of Molecular Sciences. Roč. 22, č. 19 (2021), č. článku 10838. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : intrastrand cross-link * i klenow fragment * translesion synthesis * antitumor oxaliplatin * template-primers
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/19/10838
Permanent Link: http://hdl.handle.net/11104/0329174 - 7.0551678 - ÚCHP 2022 CZ eng A - Abstract
Hamala, Vojtěch - Karban, Jindřich - Balouch, M. - Hrstka, R.
Synthesis and cytotoxicity of fluorinated amino saccharides.
Book of abstracts. 2021.
[Conference Advances in Organic, Bioorganic and Pharmaceutical Chemistry "LIBLICE 2021" /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
R&D Projects: GA MŠMT(CZ) LTC20052
Institutional support: RVO:67985858
Keywords : fluorinated carbohydrates * cytotoxic aminnosaccharides * antitumor properties
OECD category: Organic chemistry
Permanent Link: http://hdl.handle.net/11104/0326914File Download Size Commentary Version Access abstrakt_liblice_2021_Hamala.doc 0 97.3 KB Author’s postprint open-access - 8.0542896 - MBÚ 2022 RIV NL eng J - Journal Article
Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Dvořáková, Barbora - Šírová, Milada - Říhová, Blanka - Randárová, Eva - Kraus, Michal - Tomala, Jakub - Studenovský, Martin - Vondráčková, Michaela - Sedláček, Radislav - Makovický, Peter - Fučíková, J. - Vošahlíková, Š. - Spíšek, R. - Kostka, Libor - Etrych, Tomáš - Kovář, Marek
Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
Journal of Controlled Release. Roč. 332, APR 10 2021 (2021), s. 563-580. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) ED1.1.00/02.0109
Research Infrastructure: CCP - 90040
Institutional support: RVO:61388971 ; RVO:61389013 ; RVO:68378050
Keywords : Ritonavir derivate * Polymer carrier * pH-controlled release * Antitumor activity * Proteasome inhibition * STAT3 signaling inhibition
OECD category: Microbiology; Polymer science (UMCH-V)
Impact factor: 11.467, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0168365921001267
Permanent Link: http://hdl.handle.net/11104/0320232 - 9.0542792 - BFÚ 2022 RIV DE eng J - Journal Article
Novohradský, Vojtěch - Marková, Lenka - Kostrhunová, Hana - Kašpárková, Jana - Ruiz, J. - Marchan, V. - Brabec, Viktor
A Cyclometalated Ir-III Complex Conjugated to a Coumarin Derivative Is a Potent Photodynamic Agent against Prostate Differentiated and Tumorigenic Cancer Stem Cells.
Chemistry - A European Journal. Roč. 27, č. 33 (2021), s. 8547-8556. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA21-27514S
Institutional support: RVO:68081707
Keywords : calcium signals * apoptosis * antitumor agents * apoptosis * cancer stem cells
OECD category: Physical chemistry
Impact factor: 5.020, year: 2021
Method of publishing: Open access
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202100568
Permanent Link: http://hdl.handle.net/11104/0320140 - 10.0541383 - BTÚ 2021 RIV US eng J - Journal Article
Noonepalle, S. - Shen, S. - Ptáček, Jakub - Tavares, M. T. - Zhang, G. - Stránský, Jan - Pavlíček, Jiří - Ferreira, G. M. - Hadley, M. - Pelaez, G. - Bařinka, Cyril - Kozikowski, A. P. - Villagra, A.
Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.
Journal of Medicinal Chemistry. Roč. 63, č. 18 (2020), s. 10246-10262. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2018127; GA ČR GA15-19640S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : antitumor-activity * force-field * hdac6 * acetylation * gromacs * charmm * implementation * metabolism * discovery * maps
OECD category: Medicinal chemistry
Impact factor: 7.446, year: 2020
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00567
Permanent Link: http://hdl.handle.net/11104/0318945