Search results
- 1.0583492 - BFÚ 2024 RIV NL eng J - Journal Article
Sladekova, L. - Zgarbova, E. - Vrzal, R. - Vanda, D. - Soural, M. - Jakubcová, Klára - Vazquez-Gomez, Gerardo - Vondráček, Jan - Dvořák, Z.
Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines.
Toxicology Letters. Roč. 387, SEP 15 2023 (2023), s. 63-75. ISSN 0378-4274. E-ISSN 1879-3169
R&D Projects: GA ČR(CZ) GA22-00355S
Institutional support: RVO:68081707
Keywords : nuclear receptors * pxr * ahr * activation * antagonists * metabolism * tryptophan * ligands * target
OECD category: Toxicology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S037842742301055X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0351455 - 2.0580663 - ÚOCHB 2024 RIV jpn P - Patent Document
Slusher, B. - Rais, R. - Majer, Pavel - Tenora, Lukáš - Novotná, Kateřina - Alt, J.
新規なグルタミンアンタゴニストおよびそれらの使用.
[Novel glutamine antagonists and uses thereof.]
2023. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 10.10.2023. Patent Number: JP7358342. Territorial Protection: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
R&D Projects: GA MŠMT LTAUSA18166
Institutional support: RVO:61388963
Keywords : glutamine antagonists * 6-diazo-5-oxo-L-norleucine * prodrug strategies
OECD category: Organic chemistry
https://worldwide.espacenet.com/patent/search/family/065994832/publication/JP7358342B2?q=JP7358342B2
Permanent Link: https://hdl.handle.net/11104/0349426 - 3.0580592 - ÚOCHB 2024 RIV eng P - Patent Document
Slusher, B. - Rais, R. - Majer, Pavel - Tenora, Lukáš - Novotná, Kateřina - Alt, J.
Novel glutamine antagonists and uses thereof.
2022. Owner: The Johns Hopkins University - Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 24.08.2022. Patent Number: EP3692015. Territorial Protection: evropský patent podle Evropské patentové úmluvy ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
R&D Projects: GA MŠMT LTAUSA18166
Institutional support: RVO:61388963
Keywords : glutamine antagonists * 6-diazo-5-oxo-L-norleucine * prodrug strategies
OECD category: Organic chemistry
https://worldwide.espacenet.com/patent/search/family/065994832/publication/EP3692015B1?q=EP3692015B1
Permanent Link: https://hdl.handle.net/11104/0349359 - 4.0544565 - FGÚ 2022 RIV US eng J - Journal Article
Staszewski, M. - Nelic, Dominik - Jończyk, J. - Dubiel, M. - Frank, A. - Stark, H. - Bajda, M. - Jakubík, Jan - Walczyński, K.
Guanidine Derivatives: How Simple Structural Modification of Histamine H3R Antagonists Has Led to the Discovery of Potent Muscarinic M2R/M4R Antagonists.
ACS Chemical Neuroscience. Roč. 12, č. 13 (2021), s. 2503-2519. ISSN 1948-7193. E-ISSN 1948-7193
R&D Projects: GA ČR(CZ) GA19-05318S
Institutional support: RVO:67985823
Keywords : antagonists * histamine H3 receptor * muscarinic M2 receptor * muscarinic M4 receptor * structure−activity relationships * guanidine
OECD category: Physiology (including cytology)
Impact factor: 5.780, year: 2021
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acschemneuro.1c00237
Permanent Link: http://hdl.handle.net/11104/0321411 - 5.0544130 - ÚACH 2022 RIV DE eng J - Journal Article
Kadyrov, Renat - Tok, Oleg L.
Convenient Synthesis of (R)-3-[(tert-Butoxycarbonyl)amino]-piperidine and (R)-3-[(tertButoxycarbonyl)amino]azepane.
Synthesis. Roč. 53, č. 19 (2021), s. 3573-3577. ISSN 0039-7881. E-ISSN 1437-210X
Institutional support: RVO:61388980
Keywords : alpha-amino-acids * conformationally constrained analogs * pharmacophore-based molecules * scalable biocatalytic route * integrin-alpha(v)beta(3) antagonists * delta-lactams
OECD category: Inorganic and nuclear chemistry
Impact factor: 3.019, year: 2021
Method of publishing: Limited access
https://doi.org/10.1055/a-1526-7657
Permanent Link: http://hdl.handle.net/11104/0322720 - 6.0521782 - FGÚ 2020 RIV CZ eng J - Journal Article
Mareš, Pavel - Folbergrová, Jaroslava - Haugvicová, Renata - Kubová, Hana
Do stereoisomers of homocysteic acid exhibit different convulsant action in immature rats?
Physiological Research. Roč. 68, Suppl.3 (2019), S361-S366. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA18-09296S
Institutional support: RVO:67985823
Keywords : homocysteic acid * seizures * immature rats * NMDA antagonists * AMPA antagonists
OECD category: Neurosciences (including psychophysiology
Impact factor: 1.655, year: 2019
Method of publishing: Open access
http://www.biomed.cas.cz/physiolres/pdf/2019/68_S361.pdf
Permanent Link: http://hdl.handle.net/11104/0306354 - 7.0493047 - ÚI 2019 GB eng A - Abstract
Cavallari, I. - Patti, G. - Pecen, Ladislav - Lucerna, M. - Huber, K. - Rohla, M. - Renda, G. - Siller-Matula, J. M. - Ricci, F. - Kirchhof, P. - De Caterina, R.
Net Clinical Benefit of NOACs vs. VKAs in Elderly Patients with Atrial Fibrillation: a Pooled Analysis from the Real-World PREFER in AF and PREFER in AF PROLONGATION Registries.
European Heart Journal. Roč. 39, Suppl. 1 (2018), č. článku P3837. ISSN 0195-668X. E-ISSN 1522-9645
Keywords : atrial fibrillation * elderly * vitamin k antagonists * direct oral anticoagulants
Permanent Link: http://hdl.handle.net/11104/0286514 - 8.0492389 - ÚI 2019 FR eng J - Journal Article
De Caterina, R. - Brüggenjürgen, B. - Darius, H. - Köhler, S. - Lucerna, M. - Pecen, Ladislav - Renda, G. - Schilling, R. J. - Schliephacke, T. - Zamorano, J. - Le Heuzey, J.Y. - Kirchhof, P.
Quality of Life and Patient Satisfaction inPatients with Atrial Fibrillation on Stable Vitamin K Antagonist Treatment or Switched to a non-Vitamin K Antagonist Oral Anticoagulant during a 1-year follow-up: A PREFER in AF Registry Substudy.
Archives of Cardiovascular Diseases. Roč. 111, č. 2 (2018), s. 74-84. ISSN 1875-2136. E-ISSN 1875-2128
Keywords : Antagonist oral anticoagulants * Antivitamine K * Atrial fibrillation * Changement de traitement * Non-vitamin K * Patient satisfaction * Quality of life * Switching * Vitamin K antagonists
Impact factor: 2.355, year: 2018
Permanent Link: http://hdl.handle.net/11104/0285949 - 9.0490235 - FGÚ 2019 RIV GB eng J - Journal Article
Randáková, Alena - Rudajev, Vladimír - Doležal, Vladimír - Boulos, J. - Jakubík, Jan
Novel long‐acting antagonists of muscarinic ACh receptors.
British Journal of Pharmacology. Roč. 175, č. 10 (2018), s. 1731-1743. ISSN 0007-1188. E-ISSN 1476-5381
R&D Projects: GA ČR(CZ) GA17-16182S
Institutional support: RVO:67985823
Keywords : muscarinic acetylcholine receptors * long-acting antagonists * tetrahydropyridinium slats
OECD category: Physiology (including cytology)
Impact factor: 6.583, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284504 - 10.0485365 - ÚOCHB 2018 CZ eng A - Abstract
Hadzima, Martin - Tenora, Lukáš - Hudlický, Peter - Monincová, Lenka - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Design and Synthesis of Novel Prodrugs of the Glutamine Antimetabolite Acivicin.
Liblice 2017. 52nd Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2017. s. 68.
[Liblice 2017. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /52./. 03.11.2017-05.11.2017, Lázně Bělohrad]
Institutional support: RVO:61388963
Keywords : glutamine antagonists * prodrugs
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0280570