Search results
- 1.0495494 - ÚOCHB 2019 RIV GB eng J - Journal Article
Klejch, Tomáš - Pohl, Radek - Janeba, Zlatko - Sun, M. - Keough, D. T. - Guddat, L. W. - Hocková, Dana
Acyclic nucleoside phosphonates with unnatural nucleobases, favipiravir and allopurinol, designed as potential inhibitors of the human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases.
Tetrahedron. Roč. 74, č. 40 (2018), s. 5886-5897. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA ČR(CZ) GA16-06049S
Institutional support: RVO:61388963
Keywords : hypoxanthine-guanine-xanthine phosphoribosyltransferase * regioselective Mitsunobu reaction * acyclic nucleotide analogues * enzyme inhibition
OECD category: Organic chemistry
Impact factor: 2.379, year: 2018
Permanent Link: http://hdl.handle.net/11104/0288465 - 2.0346765 - ÚOCHB 2011 GB eng A - Abstract
Elbert, Tomáš
Synthesis of analogues of purine nucleotides selectively labeled by tritium on the C-8 of the purine ring and evaluation of the stability of tritium label.
Journal of Labelled Compounds and Radiopharmaceuticals. Wiley. Roč. 53, č. 3 (2010), s. 156-157. ISSN 0362-4803. E-ISSN 1099-1344.
[Workshop of the International Isotope Society - Central European Division. The Synthesis and applications of Isotopes and Isotopically Labelled Compounds /16./. 01.10.2009-02.10.2009, Bad Soden]
Institutional research plan: CEZ:AV0Z40550506
Keywords : acyclic nucleotide analogues * tritium
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0187698 - 3.0346290 - ÚOCHB 2011 RIV CZ eng J - Journal Article
Elbert, Tomáš - Břehová, Petra - Holý, Antonín
The preparation of 3-H-labeled Acyclic Nucleoside Phosphonates and Study of their Stability.
Collection of Czechoslovak Chemical Communications. Roč. 75, č. 7 (2010), s. 757-766. ISSN 0010-0765
R&D Projects: GA MŠMT 1M0508; GA AV ČR IAA400550801
Institutional research plan: CEZ:AV0Z40550506
Keywords : tritium * 3-H NMR * acyclic nucleotide analogues
Subject RIV: CC - Organic Chemistry
Impact factor: 0.853, year: 2010
Permanent Link: http://hdl.handle.net/11104/0187358 - 4.0338360 - ÚOCHB 2010 NL eng A - Abstract
Janeba, Zlatko - Holý, Antonín - Snoeck, R. - Andrei, G. - De Clercq, E. - Balzarini, J.
Synthesis and biological evaluation of acyclic nucleotide analogues ofbicyclic pyrimidine bases.
[Syntéza a biologické testování acyklických analogů nukleotidů s bicyklickou basí odvozenou od pyrimidinu.]
Antiviral Research. Elsevier. Roč. 82, č. 2 (2009), A58-A59. ISSN 0166-3542. E-ISSN 1872-9096.
[International Conference on Antiviral Research (ICAR) /22./. 03.05.2009-07.05.2009, Miami]
R&D Projects: GA MŠMT 1M0508; GA AV ČR 1QS400550501
Institutional research plan: CEZ:AV0Z40550506
Keywords : Sonogashira coupling * intramolecular cyclization * acyclic nucleotide analogues
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0182155 - 5.0315842 - ÚEM 2009 RIV SK eng M - Monography Chapter
Zídek, Zdeněk - Kmoníčková, Eva - Holý, Antonín
Cytokine-stimulatory effects of acyclic nucleotide analogues: extrapolation of immunopharmacological data from animal to human cells.
[Stimulace cytokinů acyklickými analogy nukleotidů: Extrapolace imunofarmakologických dat ze zvířecích na lidské buňky.]
Trends in pharmacological research. Bratislava: Institut of Experimental Pharmacology, 2008 - (Bauer, V.), s. 158-165. ISBN 978-80-970003-7-0
R&D Projects: GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z40550506
Keywords : Acyclic nucleotide analogues * Chemokines * Nitric oxide
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Permanent Link: http://hdl.handle.net/11104/0165933 - 6.0309740 - ÚOCHB 2008 RIV JP eng, jpn P - Patent Document
Holý, Antonín - Dvořáková, H. - De Clercq, E. - Balzarini, J.
Antiretroviral enantiomeric nucleotide analogs.
[Antiretrovirální enantiomerní nukleotidové analogy.]
Tokio: Japan Patent Office, 2004. Owner: Ústav organické chemie a biochemie AV ČR. Date of the patent registration: 04.06.2004. Date of the patent acceptance: 02.09.2004. 47 s. Patent Number: P3561272
R&D Projects: GA AV ČR IBS4055109
Institutional research plan: CEZ:AV0Z4055905
Keywords : azapurines * deazapurines * acyclic nucleotide analogues * antivirals
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0161788 - 7.0309687 - ÚOCHB 2008 RIV CA eng P - Patent Document
Holý, Antonín - Dvořáková, H. - De Clercq, E. - Balzarini, J.
Antiretroviral enantiomeric nucleotide analogs.
[Antiretrovirální enantiomerní nukleotidové analogy.]
Ottawa: Canadian Intellectual Property Office, 2007. Owner: Ústav organické chemie a biochemie AV ČR. Date of the patent registration: 01.02.1995. Date of the patent acceptance: 17.04.2007. 87 s. Patent Number: CA2141589
R&D Projects: GA AV ČR(CZ) IA45519
Keywords : azapurines * deazapurines * acyclic nucleotide analogues * antivirals
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0161747 - 8.0309685 - ÚOCHB 2008 RIV US eng P - Patent Document
Holý, Antonín - Dvořáková, H. - De Clercq, E. - Balzarini, J.
Antiretroviral enantiomeric nucleotide analogs.
[Antiretrovirální enantiomerní nukleotidové analogy.]
Alexandria: United States Patent and Trademark Office, 2003. Owner: Ústav organické chemie a biochemie AV ČR. Date of the patent registration: 02.02.1995. Date of the patent acceptance: 25.02.2003. 24 s. Patent Number: US6653296
R&D Projects: GA AV ČR(CZ) IA45519
Keywords : azapurines * deazapurines * acyclic nucleotide analogues * antivirals
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0161746 - 9.0309681 - ÚOCHB 2008 RIV US eng P - Patent Document
Balzarini, J. - De Clercq, E. - Holý, Antonín
Antiviral compounds and methods for synthesis and therapy.
[Protivirové látky a metody pro syntézu a terapii.]
Alexandria: United States Patent, 2004. Owner: Ústav organické chemie a biochemie AV ČR. Date of the patent registration: 28.06.2002. Date of the patent acceptance: 16.11.2004. 18 s. Patent Number: US6818633
Institutional research plan: CEZ:AV0Z4055905
Keywords : acyclic nucleotide analogues * antivirals
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0161743 - 10.0309680 - ÚOCHB 2008 RIV CZ cze P - Patent Document
Holý, Antonín - Dvořáková, H. - De Clercq, E. - Balzarini, J.
Sloučeniny k přípravě enentiomerních analogů nukleotidů s účinkem proti retrovirům.
[Compounds for preparation of enantiomeric nucleotide analogues with antiretroviral effect.]
Praha: Úřad průmyslového vlastnictví, 2004. Owner: Ústav organické chemie a biochemie AV ČR. Date of the patent registration: 04.08.1993. Date of the patent acceptance: 12.05.2004. 13 s. Patent Number: CZ293533
R&D Projects: GA AV ČR(CZ) IA45519
Keywords : acyclic nucleotide analogues * 2-O-tetrahydropyranyl-1-LvO-propan-1,2-diol
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0161742