Search results
- 1.0496886 - ÚEB 2019 RIV US eng J - Journal Article
Valuskova, P. - Forczek, Sándor - Farar, V. - Mysliveček, J.
The deletion of M-4 muscarinic receptors increases motor activity in females in the dark phase.
Brain and Behavior. Roč. 8, č. 8 (2018), č. článku e01057. ISSN 2162-3279. E-ISSN 2162-3279
Institutional support: RVO:61389030
Keywords : central-nervous-system * knock-out mice * acetylcholine-receptor * suprachiasmatic nucleus * locomotor-activity * sex-differences * circadian-rhythms * physiological roles * cholinergic system * rat-brain * biorhythm * intergeniculate leaflet * M-4 muscarinic receptor * motor activity * motor cortex * sex differences * striatum * suprachiasmatic nuclei * temperature * thalamus
OECD category: Clinical neurology
Impact factor: 2.072, year: 2018
Permanent Link: http://hdl.handle.net/11104/0289497File Download Size Commentary Version Access 2018_Valuskova_BRAIN AND BEHAVIOR_e01057.pdf 1 1 MB Other open-access - 2.0489202 - FGÚ 2019 RIV GB eng J - Journal Article
Boulos, J. F. - Jakubík, Jan - Boulos, J. M. - Randáková, Alena - Momirov, J.
Synthesis of novel and functionally selective non‐competitive muscarinic antagonists as chemical probes.
Chemical Biology & Drug Design. Roč. 91, č. 1 (2018), s. 93-104. ISSN 1747-0277. E-ISSN 1747-0285
R&D Projects: GA ČR(CZ) GA14-05696S; GA ČR(CZ) GBP304/12/G069
Institutional support: RVO:67985823
Keywords : G-protein-coupled receptor * muscarinic acetylcholine receptor * N-methylscopolamine * Parkinson's disease * positive allosteric modulator
OECD category: Physiology (including cytology)
Impact factor: 2.256, year: 2018
Permanent Link: http://hdl.handle.net/11104/0283661 - 3.0474014 - FGÚ 2018 RIV NL eng J - Journal Article
Gažová, Z. - Soukup, O. - Šepsová, V. - Šipošová, K. - Drtinová, L. - Jošt, P. - Spilovská, K. - Korábečný, J. - Nepovímová, E. - Fedunová, D. - Horák, Martin - Kaniaková, Martina - Wang, Z. J. - Hamouda, A. K. - Kuča, K.
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment.
Biochimica Et Biophysica Acta-Molecular Basis of Disease. Roč. 1863, č. 2 (2017), s. 607-619. ISSN 0925-4439. E-ISSN 1879-260X
R&D Projects: GA ČR(CZ) GA16-08554S
Institutional support: RVO:67985823
Keywords : amyloid * aggregation * muscarinic/nicotinic acetylcholine receptor antagonist * N-Methyl-d-aspartate receptor antagonist * Alzheimer's disease * A beta peptide * beta-secretase inhibitor
OECD category: Neurosciences (including psychophysiology
Impact factor: 5.108, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271109 - 4.0398286 - FGÚ 2014 RIV NL eng J - Journal Article
Jakubík, Jan - Randáková, Alena - Doležal, Vladimír
On homology modeling of the M-2 muscarinic acetylcholine receptor subtype.
Journal of Computer-Aided Molecular Design. Roč. 27, č. 6 (2013), s. 525-538. ISSN 0920-654X. E-ISSN 1573-4951
R&D Projects: GA ČR(CZ) GA305/09/0681; GA ČR(CZ) GBP304/12/G069
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : muscarinic acetylcholine receptor * G-protein coupled receptor * homology energy estimation * MM-GBSA
Subject RIV: ED - Physiology
Impact factor: 2.782, year: 2013
Permanent Link: http://hdl.handle.net/11104/0225814 - 5.0387214 - FGÚ 2013 RIV US eng J - Journal Article
Jindřichová, Marie - Lansdell, S. J. - Millar, N. S.
Changes in Temperature Have Opposing Effects on Current Amplitude in alpha 7 and alpha 4 beta 2 Nicotinic Acetylcholine Receptors.
PLoS ONE. Roč. 7, č. 2 (2012), e32073. ISSN 1932-6203. E-ISSN 1932-6203
Institutional research plan: CEZ:AV0Z50110509
Keywords : effect of temperature * nicotinic acetylcholine receptor * voltage-clamp recording
Subject RIV: ED - Physiology
Impact factor: 3.730, year: 2012
Permanent Link: http://hdl.handle.net/11104/0218367 - 6.0372065 - FGÚ 2012 RIV NL eng J - Journal Article
Kaniaková, Martina - Lindovský, Jiří - Krůšek, Jan - Adámek, S. - Vyskočil, František
Dual effect of lobeline on alpha 4 beta 2 rat neuronal nicotinic receptors.
European Journal of Pharmacology. Roč. 658, 2-3 (2011), s. 108-113. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA ČR(CZ) GA202/09/0806; GA AV ČR(CZ) IAA500110905; GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50110509
Keywords : lobeline * nicotinic acetylcholine receptor
Subject RIV: ED - Physiology
Impact factor: 2.516, year: 2011
Permanent Link: http://hdl.handle.net/11104/0205459 - 7.0371077 - FGÚ 2012 RIV SK eng M - Monography Chapter
Jakubík, Jan - Doležal, Vladimír - El-Fakahany, E. E. - Janíčková, Helena - Randáková, Alena - Šantrůčková, Eva
Perspectives for design of selective muscarinic agonists.
New frontiers in molecular mechanisms in neurological and psychiatric disorders. Vol. 1. Martin: Jessenius Faculty of Medicine, 2011 - (Babušiková, E.; Dobrota, D.; Lehotský, J.), s. 154-168. ISBN 978-80-88866-99-2
R&D Projects: GA ČR(CZ) GA305/09/0681; GA AV ČR(CZ) IAA500110703; GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50110509
Keywords : muscarinic acetylcholine receptor agonists * Alzheimer's disease * schizophrenia
Subject RIV: FH - Neurology
Permanent Link: http://hdl.handle.net/11104/0204705 - 8.0369969 - FGÚ 2012 RIV CZ cze J - Journal Article
Kořínek, Miloslav - Vyklický ml., Ladislav
Role cytoplazmatické membrány nervových buněk v modulaci ionotropních receptorů.
[The role of nerve cell membrane in the modulation of ionotropic receptors.]
Psychiatrie. Roč. 15, Suppl.2 (2011), s. 5-9. ISSN 1211-7579
R&D Projects: GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554; GA ČR(CZ) GPP303/11/P391; GA ČR(CZ) GA309/07/0271
Institutional research plan: CEZ:AV0Z50110509
Keywords : membrane * cholesterol * acetylcholine receptor
Subject RIV: ED - Physiology
Permanent Link: http://hdl.handle.net/11104/0203904 - 9.0359731 - FGÚ 2012 RIV US eng J - Journal Article
Lyukmanova, E. N. - Shenkarev, Z. O. - Shulepko, M. A. - Mineev, K. S. - D´Hoedt, D. - Kasheverov, I. E. - Filkin, S. Yu. - Krivolapova, A. P. - Janíčková, Helena - Doležal, Vladimír - Dolgikh, D. A. - Arseniev, A. S. - Bertrand, D. - Tsetlin, V.I. - Kirpichnikov, M. P.
NMR Structure and Action on Nicotinic Acetylcholine Receptors of Water-soluble Domain of Human LYNX1.
Journal of Biological Chemistry. Roč. 286, č. 12 (2011), s. 10618-10627. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA305/09/0681
Institutional research plan: CEZ:AV0Z50110509
Keywords : NMR structure * nicotinic acetylcholine receptor * water-soluble domain
Subject RIV: FH - Neurology
Impact factor: 4.773, year: 2011
Permanent Link: http://hdl.handle.net/11104/0197461 - 10.0355377 - FGÚ 2011 RIV US eng J - Journal Article
Grant, M.K.O. - Noetzel, M.J. - De Lorme, K.C. - Jakubík, Jan - Doležal, Vladimír - El-Fakahany, E. E.
Pharmacological Evaluation of the Long-Term Effects of Xanomeline on the M1 Muscarinic Acetylcholine Receptor.
PLoS ONE. Roč. 5, č. 12 (2010), e15722-16. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR GA305/09/0681
Institutional research plan: CEZ:AV0Z50110509
Keywords : Xanomeline * muscarinic acetylcholine receptor
Subject RIV: CE - Biochemistry
Impact factor: 4.411, year: 2010
Permanent Link: http://hdl.handle.net/11104/0194161