Search results
- 1.0558665 - MBÚ 2023 RIV US eng J - Journal Article
Surpeta, B. - Grulich, Michal - Palyzová, Andrea - Marešová, Helena - Brezovský, J.
Common Dynamic Determinants Govern Quorum Quenching Activity in N-Terminal Serine Hydrolases.
ACS Catalysis. Roč. 12, č. 11 (2022), s. 6359-6374. ISSN 2155-5435. E-ISSN 2155-5435
Institutional support: RVO:61388971
Keywords : penicillin-g acylase * homoserine-lactone-acylase * antibiotic-resistance * molecular-dynamics * substrate-binding * qm/mm calculations * specificity * health * site * perspectives * quorum quenching * N-terminal serine hydrolase * acyl-homoserine lactone acylase * penicillin G acylase * qm * mm * molecular dynamics * reaction mechanism
OECD category: Microbiology
Impact factor: 12.9, year: 2022
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acscatal.2c00569
Permanent Link: https://hdl.handle.net/11104/0332427 - 2.0534894 - MBÚ 2021 RIV DE eng J - Journal Article
Borčinová, M. - Raschmanová, H. - Zamora, I. - Looser, V. - Marešová, Helena - Hirsch, S. - Kyslík, Pavel - Kovar, K.
Production and secretion dynamics of prokaryotic Penicillin G acylase in Pichia pastoris.
Applied Microbiology and Biotechnology. Roč. 104, č. 13 (2020), s. 5787-5800. ISSN 0175-7598. E-ISSN 1432-0614
Institutional support: RVO:61388971
Keywords : fed-batch * protein-production * cultivation strategies * providencia-rettgeri * current state * growth-rate * expression * perspectives * Pichia pastoris * Penicillin G acylase
OECD category: Microbiology
Impact factor: 4.813, year: 2020
Method of publishing: Open access
https://link.springer.com/article/10.1007/s00253-020-10669-x
Permanent Link: http://hdl.handle.net/11104/0313037 - 3.0483930 - MBÚ 2018 RIV NL eng J - Journal Article
Grulich, Michal - Brezovský, J. - Štěpánek, Václav - Palyzová, Andrea - Marešová, Helena - Zahradník, Jiří - Kyslíková, Eva - Kyslík, Pavel
In-silico driven engineering of enantioselectivity of a penicillin G acylase towards active pharmaceutical ingredients.
Journal of Molecular Catalysis B-Enzymatic. Roč. 133, Supplement 1 (2016), s. 53-59. ISSN 1381-1177
Institutional support: RVO:61388971
Keywords : Docking experiments * Enantioselectivity * Penicillin G acylase
OECD category: Microbiology
Impact factor: 2.269, year: 2016
Permanent Link: http://hdl.handle.net/11104/0279725File Download Size Commentary Version Access 123_In-silico driven engineering of enantioselectivity.pdf 8 686.4 KB Publisher’s postprint require - 4.0455568 - MBÚ 2016 RIV NL eng J - Journal Article
Grulich, Michal - Brezovský, J. - Štěpánek, Václav - Palyzová, Andrea - Kyslíková, Eva - Kyslík, Pavel
Resolution of alpha/beta-amino acids by enantioselective penicillin G acylase from Achromobacter sp.
Journal of Molecular Catalysis B-Enzymatic. Roč. 122, DEC 2015 (2015), s. 240-247. ISSN 1381-1177
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971
Keywords : Penicillin G acylase * Enantioselectivity * Homologous model
Subject RIV: CE - Biochemistry
Impact factor: 2.189, year: 2015
Permanent Link: http://hdl.handle.net/11104/0256206 - 5.0435793 - MBÚ 2015 RIV DE eng J - Journal Article
Marešová, Helena - Plačková, Martina - Grulich, Michal - Kyslík, Pavel
Current state and perspectives of penicillin G acylase-based biocatalyses.
Applied Microbiology and Biotechnology. Roč. 98, č. 7 (2014), s. 2867-2879. ISSN 0175-7598. E-ISSN 1432-0614
Institutional support: RVO:61388971
Keywords : Penicillin G acylase * beta lactam biocatalysis * Enantioselectivity
Subject RIV: EE - Microbiology, Virology
Impact factor: 3.337, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239664 - 6.0428440 - MBÚ 2015 RIV DE eng J - Journal Article
Bečka, Stanislav - Štěpánek, Václav - Vyasarayani, W. R. - Grulich, Michal - Maršálek, Jaroslav - Plháčková, Kamila - Dobišová, Marie - Marešová, Helena - Plačková, Martina - Valešová, Renata - Palyzová, Andrea - Datla, A. - Ashar, T. K. - Kyslík, Pavel
Penicillin G acylase from Achromobacter sp CCM 4824 An efficient biocatalyst for syntheses of beta-lactam antibiotics under conditions employed in large-scale processes.
Applied Microbiology and Biotechnology. Roč. 98, č. 3 (2014), s. 1195-1203. ISSN 0175-7598. E-ISSN 1432-0614
Institutional support: RVO:61388971
Keywords : Achromobacter sp. * Penicillin G acylase * beta-Lactam antibiotics
Subject RIV: EE - Microbiology, Virology
Impact factor: 3.337, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233795 - 7.0388443 - MBÚ 2013 RIV eng P - Patent Document
Datla, A. - Rajasekar, V. W. - Kyslík, Pavel - Bečka, Stanislav - Krishnakant, A. T. - Yogesh, Z. S. - Nikunj, K.
Process for the preparation of penicillin or cephalosporin antibiotics.
2011. Owner: Mikrobiologický ústav AVČR, v. v. i. - Fermenta Biotech Limited MAHARASHTRA. Date of the patent acceptance: 21.09.2011. Patent Number: EP2173892
Institutional research plan: CEZ:AV0Z50200510
Keywords : Penicillin G Acylase * Achromobacter sp. CCM4824 * recombinant strain E. coli BL21(pKX1P1) CCM7394
Subject RIV: CE - Biochemistry
http://worldwide.espacenet.com/searchResults?compact=false&ST=singleline&query=EP2173892&locale=en_EP&DB=worldwide.espacenet.com
Permanent Link: http://hdl.handle.net/11104/0217342 - 8.0388437 - MBÚ 2013 eng P - Patent Document
Rajasekar, V. W. - Kyslík, Pavel - Bečka, Stanislav - Krishnakant, A. T. - Yogesh, Z. S. - Datla, A. - Nikunj, K.
Process for synthesis of a semi-synthetic penicillin or cephalosporin antibiotic using penicillin acylase biocatalyst from Achromobacter sp. CCM 4824 expressed in E.coli BL21 CCM 7394.
2012. Owner: Mikrobiologický ústav AVČR, v. v. i. - Fermenta Biotech Limited MAHARASHTRA. Date of the patent acceptance: 06.09.2012. Patent Number: IP INDIA 253959
Institutional support: RVO:61388971
Keywords : Penicillin G Acylase * Achromobacter sp. CCM4824 * recombinant strain E. coli BL21(pKX1P1) CCM7394
Subject RIV: CE - Biochemistry
http://ipindiaservices.gov.in/patentsearch/GrantedSearch/frmGrantedSearch.aspx
Permanent Link: http://hdl.handle.net/11104/0217332 - 9.0354559 - MBÚ 2011 CH eng C - Conference Paper (international conference)
Kyslík, Pavel - Marešová, Helena
Intracellular expression of gene encoding bacterial penicillin G acylase in Pichia pastoris.
Conference Proceedings of the Bio Tech 2008 and 4th Swiss-Czech Symposium. Wädenswill: Institute of Biotechnology, ZHAW, Wädenswill, 2008, s. 2-2. ISBN 978-3-905745-14-6.
[Biopharmaceuticals: why use yeasts? Wädenswill (CH), 22.05.08-23.05.08]
Institutional research plan: CEZ:AV0Z50200510
Keywords : Penicillin G acylase * heterologous expression * Pichia pastoris
Subject RIV: EE - Microbiology, Virology
Permanent Link: http://hdl.handle.net/11104/0193537 - 10.0352891 - MBÚ 2011 RIV GB eng J - Journal Article
Marešová, Helena - Marková, Zdenka - Valešová, Renata - Sklenář, Jan - Kyslík, Pavel
Heterologous expression of leader-less pga gene in Pichia pastoris: intracellular production of prokaryotic enzyme.
BMC Biotechnology. Roč. 10, - (2010), s. 1-10. E-ISSN 1472-6750
Institutional research plan: CEZ:AV0Z50200510
Keywords : PENICILLIN-G ACYLASE * ESCHERICHIA-COLI * PROVIDENCIA-RETTGERI
Subject RIV: EE - Microbiology, Virology
Impact factor: 2.859, year: 2010
Permanent Link: http://hdl.handle.net/11104/0192284