Search results
- 1.0551595 - ÚOCHB 2022 RIV NL eng M - Monography Chapter
Majerová, T. - Konvalinka, Jan
Enzymes: HIV Protease.
Encyclopedia of Biological Chemistry. Vol. 3. 3rd ed. Amsterdam: Elsevier, 2021 - (Jez, J.), s. 264-269. ISBN 978-0-12-819460-7
Institutional support: RVO:61388963
Keywords : AIDS * autoprocessing * drug design * drug resistance * enthalpy * entropy * Gag-Pol * HIV-1 protease * HIV-protease * inhibitors * precursor * SARS-CoV2
OECD category: Biochemistry and molecular biology
https://doi.org/10.1016/B978-0-12-819460-7.00172-9
Permanent Link: http://hdl.handle.net/11104/0326847 - 2.0505253 - ÚMG 2020 RIV GB eng J - Journal Article
Srb, P. - Svoboda, M. - Benda, L. - Lepšík, M. - Tarabek, J. - Šícha, V. - Gruener, B. - Grantz-Saskova, K. - Brynda, Jiří - Řezáčová, Pavlína - Konvalinka, J. - Veverka, V.
Capturing a dynamically interacting inhibitor by paramagnetic NMR spectroscopy.
Physical Chemistry Chemical Physics. Roč. 21, č. 10 (2019), s. 5661-5673. ISSN 1463-9076. E-ISSN 1463-9084
R&D Projects: GA ČR(CZ) GA15-05677S
Institutional support: RVO:68378050
Keywords : hiv-1 protease * pseudocontact shifts * proteins * assignment * exchange * restraints * complexes * molecule
OECD category: Biophysics
Impact factor: 3.430, year: 2019
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2019/CP/C9CP00416E#!divAbstract
Permanent Link: http://hdl.handle.net/11104/0297062 - 3.0503801 - ÚOCHB 2020 RIV GB eng J - Journal Article
Srb, Pavel - Svoboda, Michal - Benda, L. - Lepšík, Martin - Tarábek, Ján - Šícha, Václav - Grüner, Bohumír - Grantz Šašková, Klára - Brynda, Jiří - Řezáčová, Pavlína - Konvalinka, Jan - Veverka, Václav
Capturing a dynamically interacting inhibitor by paramagnetic NMR spectroscopy.
Physical Chemistry Chemical Physics. Roč. 21, č. 10 (2019), s. 5661-5673. ISSN 1463-9076. E-ISSN 1463-9084
R&D Projects: GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LK11205; GA ČR(CZ) GA15-05677S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : HIV-1 protease * pseudocontact shifts * proteins
OECD category: Biochemistry and molecular biology; Inorganic and nuclear chemistry (UACH-T)
Impact factor: 3.430, year: 2019
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2019/CP/C9CP00416E#!divAbstract
Permanent Link: http://hdl.handle.net/11104/0296717 - 4.0491273 - ÚOCHB 2019 CZ eng A - Abstract
Srb, Pavel - Svoboda, Michal - Benda, L. - Lepšík, Martin - Tarábek, Ján - Šícha, Václav - Grüner, Bohumír - Grantz Šašková, Klára - Brynda, Jiří - Řezáčová, Pavlína - Konvalinka, Jan - Veverka, Václav
Capturing dynamically interacting inhibitor by paramagnetic NMR spectroscopy.
Prague Protein Spring Meeting 2018: Proteins at Work. Praha: Ústav organické chemie a biochemie AV ČR, 2018 - (Votrubová, T.; Pergl Šustková, H.; Vondrášek, J.). s. 70. ISBN 978-80-86241-58-6.
[Prague Protein Spring Meeting 2018: Proteins at Work. 03.05.2018-06.05.2018, Praha]
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : paramagnetic ligands * intermolecular interactions * HIV-1 protease
OECD category: Biochemistry and molecular biology
Permanent Link: http://hdl.handle.net/11104/0285577 - 5.0394039 - ÚOCHB 2014 RIV GB eng J - Journal Article
Pokorná, Jana - Heyda, J. - Konvalinka, Jan
Ion specific effects of alkali cations on the catalytic activity of HIV-1 protease.
Faraday Discussions. Roč. 160, č. 1 (2013), s. 359-370. ISSN 1359-6640. E-ISSN 1364-5498
R&D Projects: GA ČR GBP208/12/G016; GA ČR GAP207/11/1798
Institutional support: RVO:61388963
Keywords : HIV-1 protease * ion-protein interaction * Hofmeister series * enzyme kinetics * molecular dynamics
Subject RIV: CE - Biochemistry
Impact factor: 4.194, year: 2013
Permanent Link: http://hdl.handle.net/11104/0222419 - 6.0377835 - ÚOCHB 2013 RIV cze, eng P - Patent Document
Král, V. - Cígler, Petr - Konvalinka, Jan - Kožíšek, Milan - Prejdová, Jana - Pokorná, Jana - Kräusslich, H. G. - Bodem, J. - Grüner, Bohumír - Plešek, Jaromír - Lepšík, Martin
II. Inhibitory HIV proteasy.
[HIV protease II inhibitors.]
2012. Owner: Vysoká škola chemicko-technologická - Ústav organické chemie a biochemie AV ČR - Ústav anorganické chemie AV ČR. Date of the patent acceptance: 01.02.2012. Patent Number: 303046
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z40320502
Keywords : metallacarborane * HIV-1 protease inhibition * resistance
Subject RIV: CE - Biochemistry
http://spisy.upv.cz/Patents/FullDocuments/303/303046.pdf
Permanent Link: http://hdl.handle.net/11104/0209876 - 7.0368013 - ÚOCHB 2012 RIV CZ eng J - Journal Article
Pecina, Adam - Přenosil, Ondřej - Fanfrlík, Jindřich - Řezáč, Jan - Granatier, Jaroslav - Hobza, Pavel - Lepšík, Martin
On the reliability of the corrected semiempirical quantum chemical method (PM6-DH2) for assigning the protonation states in HIV-1 protease/inhibitor complexes.
Collection of Czechoslovak Chemical Communications. Roč. 76, č. 5 (2011), s. 457-479. ISSN 0010-0765
R&D Projects: GA MŠMT LC512; GA MŠMT 1M0508; GA ČR GAP208/11/0295
Institutional research plan: CEZ:AV0Z40550506
Keywords : HIV-1 protease inhibition * protonation * QM/MM calculations
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 1.283, year: 2011
Permanent Link: http://hdl.handle.net/11104/0202490 - 8.0336385 - ÚOCHB 2010 RIV GB eng J - Journal Article
Heyda, Jan - Pokorná, Jana - Vrbka, Luboš - Vácha, Robert - Jagoda-Cwiklik, B. - Konvalinka, Jan - Jungwirth, Pavel - Vondrášek, Jiří
Ion specific effects of sodium and potassium on the catalytic activity of HIV-1 protease.
Physical Chemistry Chemical Physics. Roč. 11, č. 35 (2009), s. 7599-7604. ISSN 1463-9076. E-ISSN 1463-9084
R&D Projects: GA MŠMT LC512; GA MŠMT 1M0508; GA ČR GA203/08/0114; GA ČR GA203/06/1727
Institutional research plan: CEZ:AV0Z40550506
Keywords : HIV-1 protease * ion-protein interaction * Hofmeister series
Subject RIV: CE - Biochemistry
Impact factor: 4.116, year: 2009
Permanent Link: http://hdl.handle.net/11104/0180627 - 9.0330753 - ÚOCHB 2010 RIV US eng J - Journal Article
Grantz Šašková, Klára - Kožíšek, Milan - Řezáčová, Pavlína - Brynda, Jiří - Yashina, T. - Kagan, R. M. - Konvalinka, Jan
Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir.
Journal of Virology. Roč. 83, č. 17 (2009), s. 8810-8818. ISSN 0022-538X. E-ISSN 1098-5514
R&D Projects: GA MŠMT 1M0508
EU Projects: European Commission(XE) 37693 - HIV PI RESISTANCE
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520514
Keywords : HIV-1 protease * darunavir * X-ray structural analysis * protease inhibitor * mutations
Subject RIV: CE - Biochemistry
Impact factor: 5.150, year: 2009
Permanent Link: http://hdl.handle.net/11104/0176467 - 10.0321880 - ÚMG 2009 RIV CZ eng J - Journal Article
Kratochvíl, B. - Hušák, M. - Brynda, Jiří - Sedláček, Juraj
What is proposed by current X-ray structural analysis?
[Co nabízí současná RTG analýza?]
Chemické listy. Roč. 102, - (2008), s. 889-901. ISSN 0009-2770. E-ISSN 1213-7103
Institutional research plan: CEZ:AV0Z50520514
Keywords : powder diffraction data * protein crystallography * molecular replacement * crystal - structures * HIV-1 protease
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 0.593, year: 2008
Permanent Link: http://hdl.handle.net/11104/0170292