Search results
- 1.0571975 - ÚEB 2024 RIV NL eng J - Journal Article
Kovalová, M. - Havlíček, Libor - Djukic, Stefan - Škerlová, Jana - Peřina, M. - Pospíšil, T. - Řezníčková, E. - Řezáčová, Pavlína - Jorda, R. - Kryštof, V.
Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7.
Biomedicine & Pharmacotherapy. Roč. 161, MAY (2023), č. článku 114492. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA MŠMT LX22NPO5102
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : Cyclin-dependent kinase 7 * Inhibitor * pyrazolo[4,3-d]pyrimidine * Selectivity
OECD category: Medicinal chemistry
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.biopha.2023.114492
Permanent Link: https://hdl.handle.net/11104/0342824File Download Size Commentary Version Access 2023_Kovalova_BIOMEDICINE & PHARMACOTHERAPY_114492.pdf 2 3.3 MB Other open-access - 2.0551223 - ÚŽFG 2022 CZ eng A - Abstract
Jandová, Nela - Hampl, Marek - Procházka, J. - Kohoutek, J. - Buchtová, Marcela
Cyclin-dependent kinase 13-deficiency leads to craniofacial and neurogenesis defects during mouse embryonic development.
2nd Conference of the Visegrad Group Society for Developmental Biology. Abstracts oral and poster presentations. V4SDB, 2021. s. 64-64.
[Conference of the Visegrad Group Society for Developmental Biology /2./. 02.09.2021-05.09.2021, Szeged]
R&D Projects: GA ČR GA19-01205S
Institutional support: RVO:67985904
Keywords : cyclin-dependent kinase
OECD category: Developmental biology
Permanent Link: http://hdl.handle.net/11104/0326668 - 3.0548210 - BC 2022 RIV DE eng J - Journal Article
Bínová, E. - Bína, David - Nohýnková, E.
DNA content in Acanthamoeba during two stress defense reactions: Encystation, pseudocyst formation and cell cycle.
European Journal of Protistology. Roč. 77, Februar 2021 (2021), č. článku 125745. ISSN 0932-4739. E-ISSN 1618-0429
Institutional support: RVO:60077344
Keywords : Acanthamoeba * Cell cycle * Synchronization * Cysts * Pseudocysts * Cyclin-dependent kinase
OECD category: Biochemistry and molecular biology
Impact factor: 3.471, year: 2021
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0932473920300754?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0329073 - 4.0544833 - ÚMG 2022 RIV FR eng J - Journal Article
Jansa, J. - Jorda, R. - Škerlová, J. - Pachl, P. - Peřina, M. - Řezníčková, E. - Heger, T. - Gucký, T. - Řezáčová, Pavlína - Lyčka, A. - Kryštof, V.
Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.
European Journal of Medicinal Chemistry. Roč. 216, April (2021), č. článku 113309. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68378050
Keywords : Kinase inhibitor * Cyclin-dependent kinase 2 * imidazo[1,2-c]pyrimidin-5(6H)-one * X-ray crystallography * Co-crystal * Activity assay * itc
OECD category: Biochemistry and molecular biology
Impact factor: 7.088, year: 2021
Method of publishing: Limited access
https://www-sciencedirect-com.d360prx.biomed.cas.cz/science/article/pii/S0223523421001586?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0321645 - 5.0541414 - ÚOCHB 2022 RIV FR eng J - Journal Article
Jansa, J. - Jorda, R. - Škerlová, Jana - Pachl, Petr - Peřina, M. - Řezníčková, E. - Heger, T. - Gucký, T. - Řezáčová, Pavlína - Lyčka, A. - Kryštof, V.
Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.
European Journal of Medicinal Chemistry. Roč. 216, Apr 15 (2021), č. článku 113309. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : activity assay * Co-crystal * cyclin-dependent kinase 2 * imidazo[1,2-c]pyrimidin-5(6H)-one * ITC * kinase inhibitor * X-ray crystallography
OECD category: Biochemistry and molecular biology
Impact factor: 7.088, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.ejmech.2021.113309
Permanent Link: http://hdl.handle.net/11104/0318978 - 6.0541026 - ÚEB 2022 RIV CZ eng J - Journal Article
Spicakova, A. - Kraus, Petr - Gucký, Tomáš - Kryštof, Vladimír - Strnad, Miroslav - Bazgier, V. - Otyepka, M. - Kubickova, V. - Poruba, M. - Rácová, Z. - Zapletalová, I. - Anzenbacher, P.
in vitro and in silico Studies of Interaction of Synthetic 2,6,9-Trisubstituted Purine Kinase Inhibitors BPA-302, BP-21 and BP-117 With Liver Drug-Metabolizing Cytochromes P450.
Physiological Research. Roč. 69, SEP (2020), s. 627-636. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MZd(CZ) NV17-28231A
Institutional support: RVO:61389030
Keywords : r-roscovitine * cell-cycle * cancer * series * Cytochrome P450 inhibition * High performance liquid chromatography * Cyclin-dependent kinase inhibitor * FLT3-ITD inhibitor * Drug metabolism
OECD category: Organic chemistry
Impact factor: 1.881, year: 2020
Method of publishing: Open access
https://www.biomed.cas.cz/physiolres/pdf/2020/69_S627.pdf
Permanent Link: http://hdl.handle.net/11104/0318600File Download Size Commentary Version Access 2020_Spicakova_Physiological Research_S627.pdf 1 2.5 MB Other open-access - 7.0523373 - ÚOCHB 2021 RIV GB eng J - Journal Article
Köprülüoglu, Cemal - Dejmek, Milan - Šála, Michal - Ajani, Haresh - Hřebabecký, Hubert - Fanfrlík, Jindřich - Jorda, Radek - Dračínský, Martin - Procházková, Eliška - Šácha, Pavel - Kryštof, Vladimír - Hobza, Pavel - Lepšík, Martin - Nencka, Radim
Optimization of norbornyl-based carbocyclic nucleoside analogs as cyclin-dependent kinase 2 inhibitors.
Journal of Molecular Recognition. Roč. 33, č. 8 (2020), č. článku e2842. ISSN 0952-3499. E-ISSN 1099-1352
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:61389030
Keywords : ATP-competitive type I inhibitors * cyclin-dependent kinase 2 * protein-ligand binding * quantum mechanical scoring
OECD category: Physical chemistry
Impact factor: 2.137, year: 2020
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/abs/10.1002/jmr.2842
Permanent Link: http://hdl.handle.net/11104/0307732 - 8.0518103 - MBÚ 2020 RIV CH eng J - Journal Article
Zachleder, Vilém - Ivanov, Ivan - Vítová, Milada - Bišová, Kateřina
Cell Cycle Arrest by Supraoptimal Temperature in the Alga Chlamydomonas reinhardtii.
Cells. Roč. 8, č. 10 (2019), č. článku 1237. E-ISSN 2073-4409
R&D Projects: GA MŠMT(CZ) LO1416; GA ČR GA15-09231S
Institutional support: RVO:61388971
Keywords : cell cycle arrest * Chlamydomonas reinhardtii * cyclin-dependent kinase
OECD category: Cell biology
Impact factor: 4.366, year: 2019
Method of publishing: Open access
https://www.mdpi.com/2073-4409/8/10/1237
Permanent Link: http://hdl.handle.net/11104/0303284File Download Size Commentary Version Access 134_Cell cycle arrest by supraoptimal temperature.pdf 2 1.7 MB Publisher’s postprint require - 9.0508530 - MBÚ 2020 RIV GB eng J - Journal Article
Zachleder, Vilém - Ivanov, Ivan - Vítová, Milada - Bišová, Kateřina
Effects of cyclin-dependent kinase activity on the coordination of growth and the cell cycle in green algae at different temperatures.
Journal of Experimental Botany. Roč. 70, č. 3 (2019), s. 845-858. ISSN 0022-0957. E-ISSN 1460-2431
R&D Projects: GA MŠMT(CZ) LO1416; GA ČR GA15-09231S
Institutional support: RVO:61388971
Keywords : Cyclin-dependent kinase activity * Desmodesmus quadricauda * DNA replication
OECD category: Plant sciences, botany
Impact factor: 5.908, year: 2019
Method of publishing: Open access
https://academic.oup.com/jxb/article/70/3/845/5160063
Permanent Link: http://hdl.handle.net/11104/0299407File Download Size Commentary Version Access 134_Effects of cyclin-dependent kinase activity.pdf 4 6.1 MB Publisher’s postprint require - 10.0507694 - ÚŽFG 2020 RIV CH eng J - Journal Article
Nováková, M. - Hampl, Marek - Vrábel, D. - Procházka, Jan - Petrezselyová, Silvia - Procházková, Michaela - Sedláček, Radislav - Kavková, M. - Zikmund, T. - Kaiser, J. - Hsien-Chia, J. - Ming-Ji, F. - Buchtová, Marcela - Kohoutek, J.
Mouse Model of Congenital Heart Defects, Dysmorphic Facial Features and Intellectual Developmental Disorders as a Result of Non-functional CDK13.
Frontiers in Cell and Developmental Biology. Roč. 7, AUG 7 (2019), č. článku UNSP 155. ISSN 2296-634X. E-ISSN 2296-634X
R&D Projects: GA MŠMT EF15_003/0000460; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) LQ1604; GA MŠMT EF16_013/0001789; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT ED2.1.00/19.0395; GA ČR(CZ) GA17-14886S
Institutional support: RVO:67985904 ; RVO:68378050
Keywords : cyclin-dependent kinase (CDK) * cyclin * transcription regulation * development * mouse * cyclin-dependent kinase 13 * cyclin K
OECD category: Developmental biology
Impact factor: 5.186, year: 2019
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fcell.2019.00155/full
Permanent Link: http://hdl.handle.net/11104/0298679