Search results
- 1.0561802 - FZÚ 2024 RIV NL eng J - Journal Article
Garberová, M. - Potočňák, I. - Tvrdoňová, M. - Bago-Pilátová, M. - Bekešová, S. - Kudličková, A. - Samoľová, Erika - Kešeľáková, A. - Elečko, J. - Vilková, M.
Spectral, structural, and pharmacological studies of perillaldehyde and myrtenal based benzohydrazides.
Journal of Molecular Structure. Roč. 1271, Jan (2023), č. článku 134112. ISSN 0022-2860. E-ISSN 1872-8014
Institutional support: RVO:68378271
Keywords : hydrazone * 1H, 13C, and 15N NMR * X-ray analysis * HR-MS * antitumor activity
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 3.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.molstruc.2022.134112
Permanent Link: https://hdl.handle.net/11104/0341680 - 2.0560992 - ÚOCHB 2023 RIV US eng J - Journal Article
Santos, L. H. - Kronenberger, T. - Almeida, R. G. - Silva, E. B. - Rocha, R. E. O. - Oliveira, J. C. - Barreto, L. V. - Skinner, D. - Fajtová, Pavla - Giardini, M. A. - Woodworth, B. - Bardine, C. - Lourenço, A. L. - Craik, C. S. - Poso, A. - Podust, L. M. - McKerrow, J. H. - Siqueira-Neto, J. L. - O'Donoghue, A. J. - Da Silva Júnior, E. N. - Ferreira, R. S.
Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2.
Journal of Chemical Information and Modeling. Roč. 62, č. 24 (2022), s. 6553-6573. ISSN 1549-9596. E-ISSN 1549-960X
Institutional support: RVO:61388963
Keywords : nor-β-lapachone * Trypanosoma cruzi activity * potent antitumor activity
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acs.jcim.2c00693
Permanent Link: https://hdl.handle.net/11104/0333755 - 3.0542896 - MBÚ 2022 RIV NL eng J - Journal Article
Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Dvořáková, Barbora - Šírová, Milada - Říhová, Blanka - Randárová, Eva - Kraus, Michal - Tomala, Jakub - Studenovský, Martin - Vondráčková, Michaela - Sedláček, Radislav - Makovický, Peter - Fučíková, J. - Vošahlíková, Š. - Spíšek, R. - Kostka, Libor - Etrych, Tomáš - Kovář, Marek
Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
Journal of Controlled Release. Roč. 332, APR 10 2021 (2021), s. 563-580. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) ED1.1.00/02.0109
Research Infrastructure: CCP - 90040
Institutional support: RVO:61388971 ; RVO:61389013 ; RVO:68378050
Keywords : Ritonavir derivate * Polymer carrier * pH-controlled release * Antitumor activity * Proteasome inhibition * STAT3 signaling inhibition
OECD category: Microbiology; Polymer science (UMCH-V)
Impact factor: 11.467, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0168365921001267
Permanent Link: http://hdl.handle.net/11104/0320232 - 4.0541383 - BTÚ 2021 RIV US eng J - Journal Article
Noonepalle, S. - Shen, S. - Ptáček, Jakub - Tavares, M. T. - Zhang, G. - Stránský, Jan - Pavlíček, Jiří - Ferreira, G. M. - Hadley, M. - Pelaez, G. - Bařinka, Cyril - Kozikowski, A. P. - Villagra, A.
Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.
Journal of Medicinal Chemistry. Roč. 63, č. 18 (2020), s. 10246-10262. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2018127; GA ČR GA15-19640S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : antitumor-activity * force-field * hdac6 * acetylation * gromacs * charmm * implementation * metabolism * discovery * maps
OECD category: Medicinal chemistry
Impact factor: 7.446, year: 2020
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00567
Permanent Link: http://hdl.handle.net/11104/0318945 - 5.0509279 - ÚEB 2020 RIV CH eng J - Journal Article
Bildziukevich, Uladzimir - Özdemir, Zülal - Wimmer, Zdeněk
Recent achievements in medicinal and supramolecular chemistry of betulinic acid and its derivatives.
Molecules. Roč. 24, č. 19 (2019), č. článku 3546. E-ISSN 1420-3049
R&D Projects: GA MPO(CZ) FV10599; GA MPO(CZ) FV30300
Institutional support: RVO:61389030
Keywords : ADME parameters * Antitumor activity * Antiviral activity * Betulinic acid * Cytotoxicity * Physicochemical parameters * Structural modification * Supramolecular self-assembly
OECD category: Chemical engineering (plants, products)
Impact factor: 3.267, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.3390/molecules24193546
Permanent Link: http://hdl.handle.net/11104/0300033File Download Size Commentary Version Access 2019_Bildziukevich_MOLECULES_3546.pdf 6 646.6 KB Other open-access - 6.0506413 - BFÚ 2020 RIV US eng J - Journal Article
Zajac, Juraj - Kostrhunová, Hana - Novohradský, Vojtěch - Vrána, Oldřich - Raveendran, R. - Gibson, D. - Kašpárková, J. - Brabec, Viktor
Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin.
Journal of Inorganic Biochemistry. Roč. 156, MAR 2016 (2016), s. 89-97. ISSN 0162-0134. E-ISSN 1873-3344
R&D Projects: GA ČR(CZ) GA14-21053S; GA MŠMT(CZ) LH14317; GA MŠMT(CZ) LD14019
Institutional support: RVO:68081707
Keywords : in-vitro cytotoxicity * platinum(iv) complexes * antitumor-activity * increases sensitivity
OECD category: Biochemistry and molecular biology
Impact factor: 3.348, year: 2016
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0162013415301331?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0297657 - 7.0451455 - ÚFCH JH 2017 RIV IE eng J - Journal Article
Pruchnik, H. - Kral, Teresa - Poradowski, D. - Drynda, A. - Obmińska-Mrukowicz, B. - Hof, Martin
New cytotoxic butyltin complexes with 2-sulfobenzoic acid: Molecular interaction with lipid bilayers and DNA as well as in vitro anticancer activity.
Chemico-Biological Interactions. Roč. 243, JAN 2016 (2016), s. 107-118. ISSN 0009-2797. E-ISSN 1872-7786
R&D Projects: GA ČR GBP208/12/G016
Institutional support: RVO:61388955
Keywords : Butyltin 2-sulfobenzoates * Antitumor activity * Lipid bilayer
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 3.143, year: 2016
Permanent Link: http://hdl.handle.net/11104/0252631File Download Size Commentary Version Access 0451455.pdf 0 2.7 MB Publisher’s postprint require - 8.0435173 - BFÚ 2015 RIV GB eng J - Journal Article
Kašpárková, Jana - Thibault, T. - Kostrhunová, Hana - Štěpánková, Jana - Vojtíšková, Marie - Muchová, T. - Midoux, P. - Malinge, J.M. - Brabec, Viktor
Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer.
FEBS Journal. Roč. 281, č. 5 (2014), s. 1393-1408. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA ČR(CZ) GAP301/10/0598
Institutional support: RVO:68081707
Keywords : antitumor activity * cisplatin * DNA
Subject RIV: BO - Biophysics
Impact factor: 4.001, year: 2014
Permanent Link: http://hdl.handle.net/11104/0239098 - 9.0429932 - ÚEB 2015 RIV GB eng J - Journal Article
Cmoch, P. - Korda, A. - Rárová, Lucie - Oklešťková, Jana - Strnad, Miroslav - Luboradzki, R. - Pakulski, Z.
Synthesis and structure-activity relationship study of cytotoxic lupane-type 3 beta-O-monodesmosidic saponins with an extended C-28 side chain.
Tetrahedron. Roč. 70, č. 17 (2014), s. 2717-2730. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : BETULIN DERIVATIVES * SECONDARY ALCOHOLS * ANTITUMOR-ACTIVITY
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.641, year: 2014
Permanent Link: http://hdl.handle.net/11104/0234895File Download Size Commentary Version Access 2014_Cmoch_TETRAHEDRON_2717.pdf 1 982.1 KB Other open-access - 10.0194800 - UOCHB-X 20030106 RIV CZ eng J - Journal Article
Čapek, Petr - Otmar, Miroslav - Masojídková, Milena - Votruba, Ivan - Holý, Antonín
A facile synthesis of 9-deaza analogue of olomoucine.
Collection of Czechoslovak Chemical Communications. Roč. 68, č. 4 (2003), s. 779-791. ISSN 0010-0765
R&D Projects: GA MŠMT OC D13.20
Institutional research plan: CEZ:AV0Z4055905
Keywords : purines * antitumor activity * cytostatics
Subject RIV: CC - Organic Chemistry
Impact factor: 1.041, year: 2003
Permanent Link: http://hdl.handle.net/11104/0090471