Search results

  1. 1.
    0561212 - FZÚ 2023 RIV US eng J - Journal Article
    Nepovímová, E. - Svobodová, L. - Doležal, R. - Rostohar, Danijela … Total 30 authors
    Tacrine benzothiazoles: novel class of potential multitarget anti-Alzheimets drugs dealing with cholinergic, amyloid and mitochondrial systems.
    Bioorganic Chemistry. Roč. 107, Feb (2021), č. článku 104596. ISSN 0045-2068. E-ISSN 1090-2120
    EU Projects: European Commission(XE) 654148 - LASERLAB-EUROPE
    Institutional support: RVO:68378271
    Keywords : Alzheimer's disease * tacrine * benzothiazole * acetylcholinesterase Inhibitors * amyloid beta * ABAD * MTDLs
    OECD category: Optics (including laser optics and quantum optics)
    Impact factor: 5.307, year: 2021
    Permanent Link: https://hdl.handle.net/11104/0333898
     
     
  2. 2.
    0559646 - MBÚ 2023 RIV US eng J - Journal Article
    Velueta-Viveros, M. - Martinez-Bailen, M. - Puerta, A. - Romero-Hernandez, L. L. - Křen, Vladimír - Merino-Montiel, P. - Montiel-Smith, S. - Fernandes, Miguel X. - Moreno-Vargas, Antonio J. - Padron, Jose M. - Lopez, O. - Fernandez-Bolanos, J. G.
    Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease.
    Bioorganic Chemistry. Roč. 127, OCT 2022 (2022), č. článku 105983. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GF21-01948L
    Institutional support: RVO:61388971
    Keywords : Selenazolines * AChE * BuChE * oga * Docking simulations
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.307, year: 2021
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0045206822003881?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0333195
     
     
  3. 3.
    0559207 - MBÚ 2023 RIV US eng J - Journal Article
    Pingitore, V. - Martinez-Bailen, M. - Carmona, A. T. - Mészáros, Zuzana - Kulik, Natalia - Slámová, Kristýna - Křen, Vladimír - Bojarová, Pavla - Robina, I. - Moreno-Vargas, A. J.
    Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars.
    Bioorganic Chemistry. Roč. 120, March 2022 (2022), č. článku 105650. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GF21-01948L
    Institutional support: RVO:61388971
    Keywords : Iminosugars * Click reaction * Glycosidase inhibitors * Hexosaminidases * Multivalency * In situ screening
    OECD category: Microbiology
    Impact factor: 5.307, year: 2021
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0045206822000554?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0332674
     
     
  4. 4.
    0554712 - ÚMG 2022 RIV US eng J - Journal Article
    Jurasek, M. - Valečka, Jan - Novotný, Ivan - Kejik, Z. - Fahnrich, J. - Marešová, A. - Tauchen, J. - Bartůněk, Petr - Dolenský, B. - Jakubek, M. - Drasar, P. - Králová, Jarmila
    Synthesis and biological evaluation of cationic TopFluor cholesterol analogues.
    Bioorganic Chemistry. Roč. 117, December (2021), č. článku 105410. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR GA17-02836S; GA MŠk(CZ) LM2018130; GA MŠk(CZ) EF16_013/0001775
    Research Infrastructure: CZ-OPENSCREEN III - 90130
    Institutional support: RVO:68378050
    Keywords : TopFluor cholesterol analogues * Sterol * Cholesterol transport * Fluorescence imaging * Trafficking disorders
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.307, year: 2021
    Method of publishing: Limited access
    https://www-sciencedirect-com.d360prx.biomed.cas.cz/science/article/pii/S0045206821007872?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0329377
     
     
  5. 5.
    0548916 - BTÚ 2022 RIV NL eng J - Journal Article
    Zessin, M. - Meleshin, M. - Simic, Z. - Kalbas, D. - Arbach, M. - Gebhardt, P. - Melesina, J. - Liebscher, S. - Bordusa, F. - Sippl, W. - Bařinka, Cyril - Schutkowski, M.
    Continuous Sirtuin/HDAC (histone deacetylase) activity assay using thioamides as PET (Photoinduced Electron Transfer)-based fluorescence quencher.
    Bioorganic Chemistry. Roč. 117, DEC 2021 (2021). ISSN 0045-2068. E-ISSN 1090-2120
    Institutional support: RVO:86652036
    Keywords : Sirtuin assay * HDAC11 assay * Thioamide
    OECD category: Organic chemistry
    Impact factor: 5.307, year: 2021
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0045206821008026?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0324965
     
     
  6. 6.
    0541878 - BFÚ 2022 RIV US eng J - Journal Article
    Busto, N. - Garcia-Calvo, J. - Cuevas, J. V. - Herrera, A. - Mergny, Jean-Louis - Pons, S. - Torroba, T. - Garcia, B.
    Influence of core extension and side chain nature in targeting G-quadruplex structures with perylene monoimide derivatives.
    Bioorganic Chemistry. Roč. 108, č. 2021 (2021), č. článku 104660. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA MŠk EF15_003/0000477
    Institutional support: RVO:68081707
    Keywords : G-quadruplexes * Antiproliferative * Perylenemonoimide * DNA binding
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.307, year: 2021
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0045206821000365?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0319375
     
     
  7. 7.
    0539762 - BFÚ 2021 RIV US eng J - Journal Article
    Arevalo-Ruiz, M. - Amrane, M. - Rosu, F. - Belmonte-Reche, E. - Penalver, P. - Mergny, Jean-Louis - Carlos Morales, J.
    Symmetric and dissymmetric carbohydrate-phenyl ditriazole derivatives as DNA G-quadruplex ligands: Synthesis, biophysical studies and antiproliferative activity.
    Bioorganic Chemistry. Roč. 99, jun 2020 (2020), č. článku 103786. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA MŠk EF15_003/0000477
    Institutional support: RVO:68081707
    Keywords : gene-expression * telomere * sequence * genome * glycosides * chemistry * topology
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.275, year: 2020
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S004520681931497X?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0317459
     
     
  8. 8.
    0539200 - ÚOCHB 2022 RIV US eng J - Journal Article
    Hajduch, Jan - Fabre, Benjamin - Klopp, Benjamin - Pohl, Radek - Buděšínský, Miloš - Šolínová, Veronika - Kašička, Václav - Köprülüoglu, Cemal - Eyrilmez, Saltuk M. - Lepšík, Martin - Hobza, Pavel - Mitrová, Katarína - Lubos, Marta - Garre Hernández, María Soledad - Jiráček, Jiří
    Multipodal insulin mimetics built on adamantane or proline scaffolds.
    Bioorganic Chemistry. Roč. 107, Feb (2021), č. článku 104548. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA MŠk(CZ) EF16_019/0000729
    Institutional support: RVO:61388963
    Keywords : insulin receptor * peptidomimetics * scaffold * solid-phase peptide synthesis * hormone binding * molecular dynamics
    OECD category: Organic chemistry
    Impact factor: 5.307, year: 2021
    Method of publishing: Limited access
    https://doi.org/10.1016/j.bioorg.2020.104548
    Permanent Link: http://hdl.handle.net/11104/0317235
     
     
  9. 9.
    0538135 - ÚMG 2021 RIV US eng J - Journal Article
    Bříza, T. - Králová, Jarmila - Rimpelová, S. - Havlík, M. - Kaplánek, R. - Kejik, Z. - Martásek, P. - Mikula, I. - Dzubak, P. - Hajduch, M. - Ruml, T. - Král, V.
    Pentamethinium salts as ligands for cancer: Sulfated polysaccharide co-receptors as possible therapeutic target.
    Bioorganic Chemistry. Roč. 82, February (2019), s. 74-85. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA MŠk(CZ) LQ1604; GA MŠk(CZ) ED1.1.00/02.0109
    Institutional support: RVO:68378050
    Keywords : Anticancer activity * Cytotoxicity * Fluorescent cyanine * Pentamethinium salt * Recognition * Sulfated polysaccharides
    OECD category: Cell biology
    Impact factor: 4.831, year: 2019
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/abs/pii/S0045206817306934?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0315958
     
     
  10. 10.
    0536338 - ÚVGZ 2021 RIV US eng J - Journal Article
    Malaník, M. - Treml, J. - Leláková, V. - Nykodymová, D. - Oravec, Michal - Marek, J. - Smejkal, K.
    Anti-inflammatory and antioxidant properties of chemical constituents of Broussonetia papyrifera.
    Bioorganic Chemistry. Roč. 104, NOV (2020), č. článku 104298. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA MŠk(CZ) EF16_019/0000797
    Institutional support: RVO:86652079
    Keywords : cultivated mulberry tree * 1,3-diphenylpropane derivatives * in-vitro * flavonoids * components * bark * Broussonetia papyrifera * Anti-inflammatory * Antioxidant * NF-kappa B
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.275, year: 2020
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0045206820315960?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0314122