Search results
- 1.0617300 - ÚMG 2025 RIV US eng J - Journal Article
Špoutil, František - Dlugošová, Sylvie - Varga, Igor - Aranaz-Novaliches, Gorreti - Novosadová, Vendula - Procházková, Michaela - Sedláček, Radislav - Procházka, Jan
Semi-Automated MicroCT Analysis of Bone Anatomy and Mineralization in Mouse Models.
Current Protocols. Roč. 4, č. 2 (2024), č. článku e980. ISSN 2691-1299. E-ISSN 2691-1299
R&D Projects: GA MŠMT LM2023036; GA MŠMT EF18_046/0015861; GA MŠMT EF16_013/0001789; GA ČR GJ19-19025Y
Institutional support: RVO:68378050
Keywords : cortical bone * femur * lumbar vertebra * microCT * mineralization * skeleton phenotyping * trabecular bone
OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Method of publishing: Limited access
Result website:
https://currentprotocols.onlinelibrary.wiley.com/doi/epdf/10.1002/cpz1.980
DOI: https://doi.org/10.1002/cpz1.980
Permanent Link: https://hdl.handle.net/11104/0364422 - 2.0617297 - ÚMG 2025 RIV US eng J - Journal Article
Pavliuchenko, Nataliia - Kuzmina, Maria - Daněk, Petr - Špoutil, František - Procházka, Jan - Skopcová, Tereza - Pokorná, Jana - Sedláček, Radislav - Alberich-Jorda, Meritxell - Brdička, Tomáš
Genetic background affects neutrophil activity and determines the severity of autoinflammatory osteomyelitis in mice.
Journal of Leukocyte Biology. Roč. 117, č. 1 (2024), č. článku qiae168. ISSN 0741-5400. E-ISSN 1938-3673
R&D Projects: GA ČR(CZ) GA23-06676S; GA MŠMT LX22NPO5102; GA MŠMT LM2023036; GA MŠMT EF18_046/0015861
Institutional support: RVO:68378050
Keywords : multifocal osteomyelitis * murine model * mouse * pstpip2 * balb/c * receptors * mutation * disease * cells * chronic multifocal osteomyelitis * genetic background * neutrophil * pstpip2
OECD category: Biochemistry and molecular biology
Impact factor: 3.6, year: 2023 ; AIS: 1.395, rok: 2023
Method of publishing: Open access
Result website:
https://academic.oup.com/jleukbio/article/117/1/qiae168/7730917DOI: https://doi.org/10.1093/jleuko/qiae168
Permanent Link: https://hdl.handle.net/11104/0364243File Download Size Commentary Version Access qiae168.pdf 0 1.3 MB Publisher’s postprint open-access - 3.0617294 - ÚMG 2025 RIV GB eng J - Journal Article
Ujevic, A. - Knížková, Daniela - Synackova, A. - Pribikova, M. - Trivic, T. - Dalinskaya, A. - Drobek, Aleš - Niederlová, Veronika - Paprčková, Darina - de Guia, Roldan M. - Kašpárek, Petr - Procházka, Jan - Lábaj, Juraj - Fedosieieva, Olha - Roeck, B. F. - Mihola, Ondřej - Trachtulec, Zdeněk - Sedláček, Radislav - Štěpánek, Ondřej - Dráber, Peter
TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases.
Nature Communications. Roč. 15, č. 1 (2024), č. článku 10013. ISSN 2041-1723. E-ISSN 2041-1723
R&D Projects: GA ČR GA21-25251S; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LX22NPO5103; GA MŠMT LM2023036
EU Projects: European Commission(XE) 802878 - FunDiT
Institutional support: RVO:68378050
Keywords : nf-kappa-b * necrosis-factor receptor-1 * kinase-related kinases * linear ubiquitin * ectodermal dysplasia * gene activation * cross-talk * ikk-i * ripk1 * tbk1
OECD category: Cell biology
Impact factor: 14.7, year: 2023 ; AIS: 5.66, rok: 2023
Method of publishing: Open access
Result website:
https://www.nature.com/articles/s41467-024-54399-4DOI: https://doi.org/10.1038/s41467-024-54399-4
Permanent Link: https://hdl.handle.net/11104/0364241File Download Size Commentary Version Access Ujevic, TBK1-associated adapters.pdf 0 6.5 MB Publisher’s postprint open-access - 4.0616504 - ÚOCHB 2026 RIV GB eng J - Journal Article
Dušek, J. - Mejdrová, Ivana - Dohnalová, Klára - Smutný, T. - Chalupský, Karel - Krutáková, M. - Škoda, J. - Rashidian, A. - Pavková, I. - Škach, Kryštof - Hricová, Jana - Chocholoušková, M. - Smutná, L. - Kamaraj, R. - Hroch, M. - Leníček, M. - Mičuda, S. - Pijnenburg, D. - van Beuningen, R. - Holčapek, M. - Vítek, L. - Ingelman-Sundberg, M. - Burk, O. - Kronenberger, T. - Nencka, Radim - Pávek, P.
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model.
Nature Communications. Roč. 16, č. 1 (2025), č. článku 1418. ISSN 2041-1723. E-ISSN 2041-1723
R&D Projects: GA TA ČR(CZ) TN02000109; GA MŠMT(CZ) EH22_008/0004607; GA ČR GA22-05167S; GA MŠMT(CZ) EH23_015/0008189; GA MŠMT EF18_046/0015861; GA MŠMT LM2023036
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : pregnane-X-receptor * constitutive androstane receptor * bile-acid
Impact factor: 14.7, year: 2023 ; AIS: 5.66, rok: 2023
Method of publishing: Open access
Result website:
https://doi.org/10.1038/s41467-025-56642-yDOI: https://doi.org/10.1038/s41467-025-56642-y
Permanent Link: https://hdl.handle.net/11104/0363510File Download Size Commentary Version Access 10.1038s41467-025-56642-y.pdf 4 4 MB Publisher’s postprint open-access - 5.0605085 - ÚMG 2025 RIV US eng J - Journal Article
Teboul, L. - Amos-Landgraf, J. - Benavides, F. J. - Birling, M. - Brown, S. D. M. - Bryda, E. - Bunton-Stasyshyn, R. - Chin, H. - Crispo, M. - Delerue, F. - Dobbie, M. - Franklin, C. L. - Fuchtbauer, E. - Gao, X. - Golzio, C. - Haffner, R. - Herault, Y. - Hrabe de Angelis, M. - Lloyd, K. C. K. - Magnuson, T. R. - Montoliu, L. - Murray, S. A. - Nam, K. - Nutter, Lauryl M. J. - Pailhoux, E. - Pardo Manuel de Villena, F. - Peterson, K. - Reinholdt, L. - Sedláček, Radislav - Seong, J. K. - Shiroishi, T. - Smith, C. - Takeo, T. - Tinsley, L. - Vilotte, J. - Warming, S. - Wells, S. - Whitelaw, C. B. - Yoshiki, A. - Wang, C. - Marvel, J. - Zarubica, A. - Heaney, J. - Korf, I. F. - Lutz, C. - Kueh, A. J. - Thomas, P. Q. - Arkell, R. M. - Mann, G. J. - Pavlovic, G.
Improving laboratory animal genetic reporting: LAG-R guidelines.
Nature Communications. Roč. 15, č. 1 (2024), č. článku 5574. ISSN 2041-1723. E-ISSN 2041-1723
R&D Projects: GA MŠMT LM2023036
Institutional support: RVO:68378050
Keywords : mutation * reproducibility * husbandry * phenotype * scale * mice
OECD category: Biochemistry and molecular biology
Impact factor: 14.7, year: 2023 ; AIS: 5.66, rok: 2023
Method of publishing: Open access
Result website:
https://www.nature.com/articles/s41467-024-49439-yDOI: https://doi.org/10.1038/s41467-024-49439-y
Permanent Link: https://hdl.handle.net/11104/0362622 - 6.0604507 - ÚMG 2025 RIV US eng J - Journal Article
Rico-Llanos, G. - Špoutil, František - Bláhová, E. - Koudelka, A. - Procházková, Michaela - Czyrek, A. - Fafílek, Bohumil - Procházka, Jan - Lopez, M. G. - Křivánek, J. - Sedláček, Radislav - Krakow, D. - Nonaka, Y. - Nakamura, Y. - Krejčí, Pavel
Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.
Journal of Bone and Mineral Research. Roč. 39, č. 12 (2024), s. 1783-1792. ISSN 0884-0431. E-ISSN 1523-4681
R&D Projects: GA MŠMT LX22NPO5102; GA MZd NU23-10-00550; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT(CZ) LM2023050; GA MŠMT EF18_046/0015861
Institutional support: RVO:68378050 ; RVO:67985904
Keywords : growth * receptor * ossification * activation * closure * rescues * achondroplasia * Fgfr3 * fibroblast growth factor * treatment * postnatal * infigratinib
OECD category: Developmental biology; Virology (UZFG-Y)
Impact factor: 5.1, year: 2023 ; AIS: 1.85, rok: 2023
Method of publishing: Open access
Result website:
https://academic.oup.com/jbmr/article/39/12/1783/7826674?login=falseDOI: https://doi.org/10.1093/jbmr/zjae173
Permanent Link: https://hdl.handle.net/11104/0361937File Download Size Commentary Version Access zjae173.pdf 1 2.5 MB Publisher’s postprint open-access - 7.0604438 - ÚMG 2025 RIV CH eng J - Journal Article
Alvarez, A. M. - Trufen, Carlos Eduardo Madureira - Buri, M. V. - de Sousa, M. B. N. - Arruda-Alves, F. I. - Lichtenstein, F. - Castro de Oliveira, U. - Junqueira-de-Azevedo, I. d. L. M. - Teixeira, C. - Moreira, V.
Tumor Necrosis Factor-Alpha Modulates Expression of Genes Involved in Cytokines and Chemokine Pathways in Proliferative Myoblast Cells.
Cells. Roč. 13, č. 13 (2024), č. článku 1161. ISSN 2073-4409. E-ISSN 2073-4409
R&D Projects: GA MŠMT LM2023036
Institutional support: RVO:68378050
Keywords : nf-kappa-b * skeletal-muscle regeneration * tnf-alpha * matrix metalloproteinases * signaling pathways * early differentiation * molecular regulation * satellite cells * receptors * migration * muscle regeneration * inflammation * cytokine
OECD category: Oncology
Impact factor: 5.1, year: 2023 ; AIS: 1.34, rok: 2023
Method of publishing: Open access
Result website:
https://www.mdpi.com/2073-4409/13/13/1161DOI: https://doi.org/10.3390/cells13131161
Permanent Link: https://hdl.handle.net/11104/0361835 - 8.0601824 - ÚMG 2025 RIV CH eng J - Journal Article
Krayem, Imtissal - Grušanovič, Srdjan - Duric, Iris - Pavliuchenko, Nataliia - Daněk, Petr - Borna, Šimon - Králová, Jarmila - Skopcová, Tereza - Pokorná, Jana - Alberich-Jorda, Meritxell - Brdička, Tomáš
WBP1L regulates hematopoietic stem cell function and T cell development.
Frontiers in Immunology. Roč. 15, November (2024), č. článku 1421512. ISSN 1664-3224. E-ISSN 1664-3224
R&D Projects: GA ČR GA21-25527S; GA MŠMT LX22NPO5102; GA MŠMT LM2023036; GA MŠMT EF18_046/0015861; GA MŠMT(CZ) EH23_015/0008189; GA MŠMT(CZ) LM2023050
Institutional support: RVO:68378050
Keywords : gene-expression * progenitors * heterogeneity * populations * mice * wbp1l * transmembrane adaptor protein * hematopoiesis * hematopoietic stem cells * hematopoietic stem and progenitor cell transplantation * T cell development
OECD category: Cell biology
Impact factor: 5.7, year: 2023 ; AIS: 1.693, rok: 2023
Method of publishing: Open access
Result website:
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1421512/fullDOI: https://doi.org/10.3389/fimmu.2024.1421512
Permanent Link: https://hdl.handle.net/11104/0361970File Download Size Commentary Version Access fimmu-15-1421512.pdf 0 7 MB Publisher’s postprint open-access - 9.0601094 - ÚMG 2025 RIV CH eng J - Journal Article
Augusto Vale, Ana Matilde - Procházka, Jan - Sedláček, Radislav
Towards a Cure for Diamond-Blackfan Anemia: Views on Gene Therapy.
Cells. Roč. 13, č. 11 (2024), č. článku 920. ISSN 2073-4409. E-ISSN 2073-4409
R&D Projects: GA MŠMT LM2023036
EU Projects: European Commission(DK) 101072427 - GetRadi
Grant - others:AV ČR(CZ) StrategieAV21/29
Program: StrategieAV
Institutional support: RVO:68378050
Keywords : bone-marrow failure * lentiviral vectors * mouse model * rps19 * cell * challenges * deficiency * Diamond-Blackfan anemia * ribosomopathy * ribosomal protein genes * rare genetic disorder * hematopoietic stem cell transplantation * gene therapy * lentiviral vector * non-integrating lentiviral vector * CRISPR/Cas9
OECD category: Biochemistry and molecular biology
Impact factor: 5.1, year: 2023 ; AIS: 1.34, rok: 2023
Method of publishing: Open access
Result website:
https://www.mdpi.com/2073-4409/13/11/920DOI: https://doi.org/10.3390/cells13110920
Permanent Link: https://hdl.handle.net/11104/0358307 - 10.0601093 - ÚMG 2025 RIV US eng J - Journal Article
Janušová, Šárka - Paprčková, Darina - Michálik, Juraj - Uleri, Valeria - Drobek, Aleš - Šályová, Eva - Chorfi, M.S. - Neuwirth, Aleš - Andreyeva, Arina - Procházka, Jan - Sedláček, Radislav - Dráber, Peter - Štěpánek, Ondřej
ABIN1 is a negative regulator of effector functions in cytotoxic T cells.
Embo Reports. Roč. 25, č. 8 (2024), s. 3456-3485. ISSN 1469-221X. E-ISSN 1469-3178
R&D Projects: GA ČR GA22-18046S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT ED2.1.00/19.0395; GA MŠMT LM2023036; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2023050
EU Projects: European Commission(XE) 802878 - FunDiT
Research Infrastructure: Czech-BioImaging III - 90250
Institutional support: RVO:68378050
Keywords : nf-kappa-b * expression * kinase * cd8(+) * quantification * activation * enrichment * autophagy * signals * gamma * T Cells * Co-stimulation * Antigen Receptor * abin1 * p38
OECD category: Biochemistry and molecular biology
Impact factor: 6.5, year: 2023 ; AIS: 3.275, rok: 2023
Method of publishing: Limited access
Result website:
https://www.embopress.org/doi/full/10.1038/s44319-024-00179-6DOI: https://doi.org/10.1038/s44319-024-00179-6
Permanent Link: https://hdl.handle.net/11104/0358306File Download Size Commentary Version Access janusova-et-al-2024-abin1-is-a-negative-regulator-of-effector-functions-in-cytotoxic-t-cells.pdf 0 5.9 MB Publisher’s postprint open-access