Search results
- 1.0574532 - BTÚ 2024 RIV US eng J - Journal Article
Motlová, Lucia - Šnajdr, Ivan - Kutil, Zsofia - Andris, Erik - Ptáček, Jakub - Novotná, Adéla - Nováková, Zora - Havlínová, Barbora - Tueckmantel, W. - Dráberová, Helena - Majer, Pavel - Schutkowski, M. - Kozikowski, A. - Rulíšek, Lubomír - Bařinka, Cyril
Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6).
ACS Chemical Biology. Roč. 18, č. 7 (2023), s. 1594-1610. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GA21-31806S; GA ČR(CZ) GA23-05940S; GA MŠMT(CZ) LUAUS23247
Research Infrastructure: CIISB III - 90242; EATRIS-CZ IV - 90253
Institutional support: RVO:86652036 ; RVO:61388963
Keywords : BASIS-SETS * COSMO * ENERGY * REFINEMENT
OECD category: Biochemistry and molecular biology
Impact factor: 4, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acschembio.3c00212
Permanent Link: https://hdl.handle.net/11104/0347139 - 2.0571923 - BTÚ 2024 RIV CH eng J - Journal Article
Zessin, M. - Meleshin, M. - Hilscher, S. - Schiene-Fischer, C. - Bařinka, Cyril - Jung, M. - Schutkowski, M.
Continuous Fluorescent Sirtuin Activity Assay Based on Fatty Acylated Lysines.
International Journal of Molecular Sciences. Roč. 24, č. 8 (2023), č. článku 7416. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-31806S
Institutional support: RVO:86652036
Keywords : histone deacetylases * sirtuins * fluorescence quenching * sirtuin inhibitors
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/24/8/7416
Permanent Link: https://hdl.handle.net/11104/0342895 - 3.0571548 - BTÚ 2024 RIV CH eng J - Journal Article
Ptáček, Jakub - Šnajdr, Ivan - Schimer, Jiří - Kutil, Zsofia - Mikesova, Jana - Baranová, Petra - Havlínová, Barbora - Tueckmantel, W. - Majer, Pavel - Kozikowski, A. - Bařinka, Cyril
Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells.
International Journal of Molecular Sciences. Roč. 24, č. 5 (2023), č. článku 4720. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-31806S; GA MŠMT LX22NPO5102
Institutional support: RVO:86652036 ; RVO:61388963
Keywords : metallohydrolase * histone deacetylase * inhibitor profiling * tubulin * histone acetylation * nanoBRET
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/24/5/4720
Permanent Link: https://hdl.handle.net/11104/0342903 - 4.0568950 - BTÚ 2024 RIV GB eng J - Journal Article
Shukla, Shivam - Komárek, Jan - Nováková, Zora - Nedvědová, Jana - Ustinova, Kseniya - Vaňková, Pavla - Kadek, A. - Uetrecht, C. - Mertens, H. - Bařinka, Cyril
In-solution structure and oligomerization of human histone deacetylase 6-an integrative approach.
FEBS Journal. Roč. 290, č. 3 (2023), s. 821-836. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA ČR(CZ) GA21-31806S
Research Infrastructure: CIISB III - 90242
Institutional support: RVO:86652036
Keywords : acetylation * analytical ultracentrifugation * intrinsically disordered regions * oligomerization * small-angle X-ray scattering
OECD category: Biochemistry and molecular biology
Impact factor: 5.4, year: 2022
Method of publishing: Limited access
https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16616
Permanent Link: https://hdl.handle.net/11104/0342353 - 5.0558797 - BTÚ 2023 RIV US eng J - Journal Article
Zessin, M. - Meleshin, M. - Praetorius, L. - Sippl, W. - Bařinka, Cyril - Schutkowski, M.
Uncovering Robust Delactoylase and Depyruvoylase Activities of HDAC Isoforms.
ACS Chemical Biology. Roč. 17, č. 6 (2022), s. 1364-1375. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GA21-31806S
Institutional support: RVO:86652036
Keywords : histone crotonylation * lysine * inhibitor * substrate
OECD category: Biochemistry and molecular biology
Impact factor: 4, year: 2022
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acschembio.1c00863
Permanent Link: https://hdl.handle.net/11104/0332584 - 6.0556614 - BTÚ 2023 RIV US eng J - Journal Article
Kutil, Zsofia - Meleshin, M. - Baranová, Petra - Havlínová, Barbora - Schutkowski, M. - Bařinka, Cyril
Characterization of the class IIa histone deacetylases substrate specificity.
FASEB Journal. Roč. 36, č. 5 (2022), č. článku e22287. ISSN 0892-6638. E-ISSN 1530-6860
R&D Projects: GA ČR(CZ) GA21-31806S
Institutional support: RVO:86652036
Keywords : controls chondrocyte hypertrophy * catalytic-activity * acetylation * phosphorylation
OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Impact factor: 4.8, year: 2022
Method of publishing: Limited access
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101663R
Permanent Link: http://hdl.handle.net/11104/0332031 - 7.0555060 - BTÚ 2023 RIV CH eng J - Journal Article
Ibrahim, H. - Abdelsalam, M. - Zeyn, Y. - Zessin, M. - Mustafa, A. - Fischer, M. - Zeyen, P. - Sun, P. - Buelbuel, E. - Vecchio, A. - Erdmann, F. - Schmidt, M. - Robaa, D. - Bařinka, Cyril - Romier, C. - Schutkowski, M. - Kraemer, O. - Sippl, W.
Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
International Journal of Molecular Sciences. Roč. 23, č. 1 (2022), č. článku 369. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA21-31806S
Institutional support: RVO:86652036
Keywords : EFFICIENT GENERATION * EPIGENETIC THERAPY * AM1-BCC MODEL
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/1/369
Permanent Link: http://hdl.handle.net/11104/0332121