Search results
- 1.0573031 - ÚOCHB 2024 RIV US eng J - Journal Article
Zmudzinski, M. - Rut, W. - Olech, K. - Granda, J. - Giurg, M. - Burda-Grabowska, M. - Kaleta, R. - Zgarbová, Michala - Kasprzyk, R. - Zhang, L. - Sun, X. - Lv, Z. - Nayak, D. - Kesik-Brodacka, M. - Olsen, S. K. - Weber, Jan - Hilgenfeld, R. - Jemielity, J. - Drag, M.
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase.
Scientific Reports. Roč. 13, June (2023), č. článku 9161. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : organoselenium compounds * synthetic methodology * SARS
OECD category: Virology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-023-35907-w
Permanent Link: https://hdl.handle.net/11104/0343565 - 2.0544834 - ÚMG 2022 RIV US eng J - Journal Article
Kryštůfek, R. - Šácha, P. - Starková, J. - Brynda, Jiří - Hradilek, M. - Tloušťová, E. - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, P. - Hájek, M. - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, J.
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:68378050
Keywords : immunodeficiency-virus hiv * in-vitro * virulence factors * type-1 protease * inhibitors * pepsin * specificity * meningitis * expression * strategies
OECD category: Biochemistry and molecular biology
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0321646 - 3.0543118 - ÚOCHB 2022 RIV US eng J - Journal Article
Kryštůfek, Robin - Šácha, Pavel - Starková, Jana - Brynda, Jiří - Hradilek, Martin - Tloušťová, Eva - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, Pavel - Hájek, Miroslav - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, Jan
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : immunodeficiency virus HIV * in-vitro * virulence factors
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0320402