Search results

  1. 1.
    0604812 - ÚMG 2025 RIV GB eng J - Journal Article
    Outlá, Zuzana - Oyman Eyrilmez, Gizem - Korelová, Kateřina - Přechová, Magdalena - Frick, L. - Sarnová, Lenka - Bisht, Piyush - Novotná, Petra - Kosla, Jan - Bortel, P. - Borutzki, Y. - Bileck, A. - Gener, Ch. - Rahbari, M. - Rahbari, N. - Birgin, E. - Kvasnicová, B. - Gálisová, A. - Sulková, K. - Bauer, A. - Jobe, N. - Tolde, O. - Sticová, E. - Rosel, D. - O’Connor, T. - Otáhal, M. - Jirák, D. - Heikenwälder, M. - Wiche, G. - Meier-Menches, S. M. - Gregor, M.
    Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis.
    eLife. ISSN 2050-084X. E-ISSN 2050-084X
    R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2023050; GA MŠMT(CZ) LM2018126; GA MŠMT(CZ) LQ1604; GA MŠMT LO1419; GA MŠMT(CZ) LM2015040; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:68378050
    OECD category: Biochemistry and molecular biology
    Result website:
    https://elifesciences.org/reviewed-preprints/102205v1DOI: https://doi.org/https://doi.org/10.7554/eLife.102205.1
    Permanent Link: https://hdl.handle.net/11104/0362317
     
  2. 2.
    0604507 - ÚMG 2025 RIV US eng J - Journal Article
    Rico-Llanos, G. - Špoutil, František - Bláhová, E. - Koudelka, A. - Procházková, Michaela - Czyrek, A. - Fafílek, Bohumil - Procházka, Jan - Lopez, M. G. - Křivánek, J. - Sedláček, Radislav - Krakow, D. - Nonaka, Y. - Nakamura, Y. - Krejčí, Pavel
    Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.
    Journal of Bone and Mineral Research. Roč. 39, č. 12 (2024), s. 1783-1792. ISSN 0884-0431. E-ISSN 1523-4681
    R&D Projects: GA MŠMT LX22NPO5102; GA MZd NU23-10-00550; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT(CZ) LM2023050; GA MŠMT EF18_046/0015861
    Institutional support: RVO:68378050 ; RVO:67985904
    Keywords : growth * receptor * ossification * activation * closure * rescues * achondroplasia * Fgfr3 * fibroblast growth factor * treatment * postnatal * infigratinib
    OECD category: Developmental biology
    Impact factor: 5.1, year: 2023 ; AIS: 1.847, rok: 2023
    Method of publishing: Open access
    Result website:
    https://academic.oup.com/jbmr/article/39/12/1783/7826674?login=falseDOI: https://doi.org/10.1093/jbmr/zjae173
    Permanent Link: https://hdl.handle.net/11104/0361937
     
    FileDownloadSizeCommentaryVersionAccess
    zjae173.pdf12.5 MBPublisher’s postprintopen-access
     
  3. 3.
    0601090 - ÚMG 2025 RIV US eng J - Journal Article
    Buccheri, Valeria - Pasulka, Josef - Malík, Radek - Loubalová, Zuzana - Táborská, Eliška - Horvat, Filip - Kulmann, Marcos Iuri Roos - Jeníčková, Irena - Procházka, Jan - Sedláček, Radislav - Svoboda, Petr
    Functional canonical RNAi in mice expressing a truncated Dicer isoform and long dsRNA.
    Embo Reports. Roč. 25, č. 7 (2024), s. 2896-2913. ISSN 1469-221X. E-ISSN 1469-3178
    R&D Projects: GA ČR GX20-03950X; GA MŠMT LO1419; GA MŠMT(CZ) LM2018126
    Research Infrastructure: e-INFRA CZ II - 90254; ELIXIR CZ III - 90255
    Institutional support: RVO:68378050
    Keywords : double-stranded-rna * gene-expression * microrna biogenesis * mammalian-cells * mouse * interference * oocytes * potent * inhibition * mirtrons * Dicer * dsRNA * Mirtron * siRNA * pkr
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.5, year: 2023 ; AIS: 3.271, rok: 2023
    Method of publishing: Open access
    Result website:
    https://www.embopress.org/doi/full/10.1038/s44319-024-00148-zDOI: https://doi.org/10.1038/s44319-024-00148-z
    Permanent Link: https://hdl.handle.net/11104/0358303
     
  4. 4.
    0598886 - ÚMG 2025 RIV US eng J - Journal Article
    Nickl, Petr - Jeníčková, Irena - Eliáš, Jan - Kašpárek, Petr - Bařinka, Cyril - Kopkanová, Jana - Sedláček, Radislav
    Multistep allelic conversion in mouse pre-implantation embryos by AAV vectors.
    Scientific Reports. Roč. 14, č. 1 (2024), č. článku 20160. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT LX22NPO5102
    Institutional support: RVO:68378050 ; RVO:86652036
    Keywords : gene * electroporation * zygotes * knockin * cells * aav * 3r * Gene delivery * Flp/FRT * ivf * Site-specific recombinase
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.8, year: 2023 ; AIS: 1.059, rok: 2023
    Method of publishing: Open access
    Result website:
    https://www.nature.com/articles/s41598-024-70853-1DOI: https://doi.org/10.1038/s41598-024-70853-1
    Permanent Link: https://hdl.handle.net/11104/0356463
     
    FileDownloadSizeCommentaryVersionAccess
    s41598-024-70853-1 (1).pdf03 MBPublisher’s postprintopen-access
     
  5. 5.
    0597892 - ÚMG 2025 RIV US eng J - Journal Article
    Sinigaglia, K. - Cherian, A. - Du, Q. - Lacovich, V. - Vukic, D. - Melicherová, J. - Linhartová, P. - Zerad, L. - Stejskal, S. - Malík, Radek - Procházka, Jan - Bondurand, N. - Sedláček, Radislav - O'Connell, M. A. - Keegan, L. P.
    An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation.
    Cell Reports. Roč. 43, č. 8 (2024), č. článku 114618. ISSN 2211-1247. E-ISSN 2211-1247
    R&D Projects: GA MŠMT(CZ) LM2023050; GA MŠMT(CZ) LM2018126
    Grant - others:Ministerstvo školství, mládeže a tělovýchovy - GA MŠk(CZ) LM2018140
    Research Infrastructure: e-INFRA CZ - 90140
    Institutional support: RVO:68378050
    Keywords : rna * recognition * dimerization * elf2-alpha
    OECD category: Biochemistry and molecular biology
    Impact factor: 7.5, year: 2023 ; AIS: 3.775, rok: 2023
    Method of publishing: Open access
    Result website:
    https://www.sciencedirect.com/science/article/pii/S2211124724009689?via%3DihubDOI: https://doi.org/10.1016/j.celrep.2024.114618
    Permanent Link: https://hdl.handle.net/11104/0356362
     
  6. 6.
    0584844 - ÚMG 2025 RIV GB eng J - Journal Article
    Turková, T. - Kokavec, J. - Zikmund, T. - Dibus, Nikol - Pimková, K. - Němec, D. - Holečková, M. - Rusková, L. - Sedláček, Radislav - Čermák, Lukáš - Stopka, T.
    Differential requirements for Smarca5 expression during hematopoietic stem cell commitment.
    Communications Biology. Roč. 7, č. 1 (2024), č. článku 244. E-ISSN 2399-3642
    R&D Projects: GA MZd NU22-05-00374; GA MZd NU21-08-00312; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA ČR(CZ) GA24-10435S
    Institutional support: RVO:68378050
    Keywords : iswi * mice * mechanisms * snf2h
    OECD category: Hematology
    Impact factor: 5.2, year: 2023 ; AIS: 2.034, rok: 2023
    Method of publishing: Open access
    Result website:
    https://www.nature.com/articles/s42003-024-05917-zDOI: https://doi.org/10.1038/s42003-024-05917-z
    Permanent Link: https://hdl.handle.net/11104/0352849
     
  7. 7.
    0584843 - ÚMG 2025 US eng J - Journal Article
    Sunny, Sweetu Susan - Láchová, Jitka - Kašpárek, P. - Pálková, Marcela - Špoutil, František - Procházka, Jan - Sedláček, Radislav - Lišková, P. - Kozmik, Zbyněk
    Ovol2 promoter mutations in mice and human illuminate species-specific phenotypic divergence.
    Human Molecular Genetics. Roč. 33, č. 6 (2024), s. 491-500. ISSN 0964-6906. E-ISSN 1460-2083
    R&D Projects: GA ČR GA21-27364S; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
    Institutional support: RVO:68378050
    Keywords : polymorphous corneal-dystrophy * epithelial-mesenchymal transition * noncoding mutations * drosophila-ovo * expression * zeb1 * gene * classification * identification * suppression * cornea * ppcd1 * Ovol2 * pathogenic variant * corneal endothelium
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.1, year: 2023 ; AIS: 1.692, rok: 2023
    Method of publishing: Limited access
    Result website:
    https://academic.oup.com/hmg/article-abstract/33/6/491/7424510?redirectedFrom=fulltext&login=falseDOI: https://doi.org/10.1093/hmg/ddad195
    Permanent Link: https://hdl.handle.net/11104/0352866
     
  8. 8.
    0581626 - ÚMG 2024 RIV US eng J - Journal Article
    Kubik-Zahorodna, Agnieszka - Procházka, Jan - Sedláček, Radislav
    Behavioral Characterization of an Angelman Syndrome Mouse Model.
    Jove-Journal of Visualized Experiments. Roč. 2023, č. 200 (2023), č. článku e65182. ISSN 1940-087X. E-ISSN 1940-087X
    R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT LM2023036
    Institutional support: RVO:68378050
    Keywords : Angelman Syndrome * Animals * Behavior * Animal * Disease Models
    OECD category: Biochemistry and molecular biology
    Impact factor: 1.2, year: 2023 ; AIS: 0.417, rok: 2023
    Method of publishing: Limited access
    Result website:
    https://www.jove.com/t/65182/behavioral-characterization-of-an-angelman-syndrome-mouse-modelDOI: https://doi.org/10.3791/65182
    Permanent Link: https://hdl.handle.net/11104/0349879
     
  9. 9.
    0579872 - ÚMG 2024 RIV GB eng J - Journal Article
    Gruper, Y. - Wolff, A. S. B. - Glanz, L. - Špoutil, František - Marthinussen, M. C. - Osičková, Adriana - Herzig, Y. - Goldfarb, Y. - Aranaz-Novaliches, Gorreti - Dobeš, J. - Kadouri, N. - Ben-Nun, O. - Binyamin, A. - Lavi, B. - Givony, T. - Khalaila, R. - Gome, T. - Wald, Tomáš - Mrázková, Blanka - Sochen, C. - Besnard, M. - Ben-Dor, S. - Feldmesser, E. - Orlova, E. M. - Hegedus, C. - Lampe, I. - Papp, T. - Felszeghy, S. - Sedláček, Radislav - Davidovich, E. - Tal, N. - Shouval, D. S. - Shamir, R. - Guillonneau, C. - Szondy, Z. - Lundin, K. E. A. - Osička, Radim - Procházka, Jan - Husebye, E. S. - Abramson, J.
    Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
    Nature. Roč. 624, č. 7992 (2023), s. 653-662. ISSN 0028-0836. E-ISSN 1476-4687
    R&D Projects: GA MŠMT(CZ) LM2023053; GA MŠMT(CZ) LM2018126; GA MŠMT LM2023036; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA ČR GJ19-19025Y; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
    Institutional support: RVO:68378050 ; RVO:61388971
    Keywords : antibody * enamel * immune response * protein * tolerance * tooth
    OECD category: Biochemistry and molecular biology; Immunology (MBU-M)
    Impact factor: 50.5, year: 2023 ; AIS: 24.739, rok: 2023
    Method of publishing: Limited access
    Result website:
    https://www.nature.com/articles/s41586-023-06776-0DOI: https://doi.org/10.1038/s41586-023-06776-0
    Permanent Link: https://hdl.handle.net/11104/0348991
     
  10. 10.
    0578356 - ÚMG 2024 RIV US eng J - Journal Article
    Kemmler, C. L. - Smolíková, Jana - Moran, H. R. - Mannion, B. J. - Knapp, D. - Lim, F. - Czarkwiani, A. - Aguayo, V. H. - Rapp, V. - Fitch, O. E. - Botschi, S. - Selleri, L. - Farley, E. - Braasch, I. - Yun, M. - Visel, A. - Osterwalder, M. - Mosimann, C. - Kozmik, Zbyněk - Burger, A.
    Conserved enhancers control notochord expression of vertebrate Brachyury.
    Nature Communications. Roč. 14, č. 1 (2023), s. 6594. ISSN 2041-1723. E-ISSN 2041-1723
    R&D Projects: GA MŠMT(CZ) LM2018126; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR GA23-07056S
    Institutional support: RVO:68378050
    Keywords : transcription factors * Brachyury/T/TBXT * notochord expression
    OECD category: Biochemistry and molecular biology
    Impact factor: 14.7, year: 2023 ; AIS: 5.656, rok: 2023
    Method of publishing: Open access
    Result website:
    https://www.nature.com/articles/s41467-023-42151-3DOI: https://doi.org/10.1038/s41467-023-42151-3
    Permanent Link: https://hdl.handle.net/11104/0347411
     

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