Search results
- 1.0574383 - ÚOCHB 2024 RIV NL eng J - Journal Article
Dejmek, Milan - Brázdová, Andrea - Otava, Tomáš - Pimková Polidarová, Markéta - Klíma, Martin - Smola, Miroslav - Vavřina, Zdeněk - Buděšínský, Miloš - Dračínský, Martin - Liboska, Radek - Bouřa, Evžen - Birkuš, Gabriel - Nencka, Radim
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy.
European Journal of Medicinal Chemistry. Roč. 259, November (2023), č. článku 115685. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LX22NPO5103; GA MZd(CZ) NU20-05-00472
Research Infrastructure: CCP II - 90126
Institutional support: RVO:61388963
Keywords : cyclic dinucleotides * STING * cancer * intratumoral administration * immunotherapy
OECD category: Medicinal chemistry
Impact factor: 6.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2023.115685
Permanent Link: https://hdl.handle.net/11104/0344716File Download Size Commentary Version Access 10.1016j.ejmech.2023.115685.pdf 0 5.2 MB Publisher’s postprint open-access
Research data: PDB - 2.0570640 - ÚOCHB 2024 RIV CZ eng J - Journal Article
Vaneková, Lenka - Pimková Polidarová, Markéta - Charvát, Vilém - Vavřina, Zdeněk - Veverka, Václav - Birkuš, Gabriel - Brázdová, Andrea
Development and Characterization of a Chronic Hepatitis B Murine Model With a Mutation in the START Codon of an HBV Polymerase.
Physiological Research. Roč. 72, č. 1 (2023), s. 37-47. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : chronic hepatitis B murine model * HBsAg * HBcAg * pAAV system * minicircle HBV
OECD category: Medicinal chemistry
Impact factor: 2.1, year: 2022
Method of publishing: Open access
https://doi.org/10.33549/physiolres.934979
Permanent Link: https://hdl.handle.net/11104/0341954 - 3.0565954 - ÚOCHB 2024 RIV US eng J - Journal Article
Pimková Polidarová, Markéta - Vaneková, Lenka - Břehová, Petra - Dejmek, Milan - Vavřina, Zdeněk - Birkuš, Gabriel - Brázdová, Andrea
Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells.
ACS Infectious Diseases. Roč. 9, č. 1 (2023), s. 23-32. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : chronic hepatitis B * STING * nonparenchymal liver cells * antiviral immunity * cytokine * HBV-persistent mouse model
OECD category: Biochemistry and molecular biology
Impact factor: 5.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.2c00424
Permanent Link: https://hdl.handle.net/11104/0337421 - 4.0563508 - ÚOCHB 2023 RIV CH eng J - Journal Article
Vaneková, Lenka - Pimková Polidarová, Markéta - Veverka, Václav - Birkuš, Gabriel - Brázdová, Andrea
Multiparametric Flow Cytometry-Based Immunophenotyping of Mouse Liver Immune Cells.
Methods and Protocols. Roč. 5, č. 5 (2022), č. článku 70. E-ISSN 2409-9279
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : flow cytometry * immunophenotyping * mouse liver * PBS-based liver perfusion * non-parenchymal cells
OECD category: Biochemistry and molecular biology
Impact factor: 2.4, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/mps5050070
Permanent Link: https://hdl.handle.net/11104/0335459 - 5.0556396 - ÚOCHB 2023 RIV US eng J - Journal Article
Pimková Polidarová, Markéta - Břehová, Petra - Dejmek, Milan - Birkuš, Gabriel - Brázdová, Andrea
STING Agonist-Mediated Cytokine Secretion Is Accompanied by Monocyte Apoptosis.
ACS Infectious Diseases. Roč. 8, č. 3 (2022), s. 463-471. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : STING * cGAS-STING pathway * apoptosis * monocytes * proinflammatory cytokines * interferons
OECD category: Biochemistry and molecular biology
Impact factor: 5.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.1c00554
Permanent Link: http://hdl.handle.net/11104/0330938 - 6.0543611 - ÚOCHB 2022 RIV US eng J - Journal Article
Pimková Polidarová, Markéta - Břehová, Petra - Kaiser, Martin Maxmilian - Smola, Miroslav - Dračínský, Martin - Smith, Joshua - Marek, Aleš - Dejmek, Milan - Šála, Michal - Gutten, Ondrej - Rulíšek, Lubomír - Novotná, Barbora - Brázdová, Andrea - Janeba, Zlatko - Nencka, Radim - Bouřa, Evžen - Páv, Ondřej - Birkuš, Gabriel
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP).
Journal of Medicinal Chemistry. Roč. 64, č. 11 (2021), s. 7596-7616. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
Institutional support: RVO:61388963
Keywords : DNA sensor * interferon genes * cyclic GMP-AMP
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c00301
Permanent Link: http://hdl.handle.net/11104/0320799 - 7.0519161 - ÚOCHB 2020 RIV US eng J - Journal Article
Novotná, Barbora - Vaneková, Lenka - Zavřel, Martin - Buděšínský, Miloš - Dejmek, Milan - Smola, Miroslav - Gutten, Ondrej - Tehrani, Zahra Aliakbar - Pimková Polidarová, Markéta - Brázdová, Andrea - Liboska, Radek - Štěpánek, Ivan - Vavřina, Zdeněk - Jandušík, Tomáš - Nencka, Radim - Rulíšek, Lubomír - Bouřa, Evžen - Brynda, Jiří - Páv, Ondřej - Birkuš, Gabriel
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
Journal of Medicinal Chemistry. Roč. 62, č. 23 (2019), s. 10676-10690. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
Institutional support: RVO:61388963
Keywords : cyclic GMP-AMP * cytosolic DNA sensor * di-GMP
OECD category: Organic chemistry
Impact factor: 6.205, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.9b01062
Permanent Link: http://hdl.handle.net/11104/0304187