Search results
- 1.0583190 - ÚOCHB 2025 RIV US eng J - Journal Article
Klíma, Martin - Dejmek, Milan - Duchoslav, Vojtěch - Eisenreichová, Andrea - Šála, Michal - Chalupský, Karel - Chalupská, Dominika - Novotná, Barbora - Birkuš, Gabriel - Nencka, Radim - Bouřa, Evžen
Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Structure. Roč. 32, č. 4 (2024), s. 433-439. ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.str.2024.01.008
Permanent Link: https://hdl.handle.net/11104/0351191File Download Size Commentary Version Access 10.1016j.str.2024.01.008.pdf 0 3.1 MB Publisher’s postprint open-access - 2.0549413 - ÚOCHB 2022 RIV US eng J - Journal Article
Novotná, Barbora - Holá, Lucie - Staś, Monika - Gutten, Ondrej - Smola, Miroslav - Zavřel, Martin - Vavřina, Zdeněk - Buděšínský, Miloš - Liboska, Radek - Chevrier, Florian - Dobiaš, Juraj - Bouřa, Evžen - Rulíšek, Lubomír - Birkuš, Gabriel
Enzymatic Synthesis of 3′-5′, 3′-5′ Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
Biochemistry. Roč. 60, č. 48 (2021), s. 3714-3727. ISSN 0006-2960
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
Institutional support: RVO:61388963
Keywords : cytosolic DNA sensor * c-di-GMP * structural analysis
OECD category: Biochemistry and molecular biology
Impact factor: 3.321, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.biochem.1c00692
Permanent Link: http://hdl.handle.net/11104/0325428 - 3.0545469 - ÚOCHB 2022 RIV DE eng J - Journal Article
Hejdánková, Zuzana - Vaněk, Václav - Sedlák, František - Procházka, Jan - Diederichs, Audrey - Kereiche, Sami - Novotná, Barbora - Buděšínský, Miloš - Birkuš, Gabriel - Grantz Šašková, Klára - Cígler, Petr
Lipid Nanoparticles for Broad-Spectrum Nucleic Acid Delivery.
Advanced Functional Materials. Roč. 31, č. 47 (2021), č. článku 2101391. ISSN 1616-301X. E-ISSN 1616-3028
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2018126; GA MŠMT EF16_013/0001789; GA MŠMT EF18_046/0015861; GA MŠMT ED2.1.00/19.0395; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388963 ; RVO:68378050
Keywords : cyclic dinucleotides * DNA * drug delivery * lipid nanoparticles * RNA
OECD category: Biochemistry and molecular biology
Impact factor: 19.924, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/adfm.202101391
Permanent Link: http://hdl.handle.net/11104/0322155 - 4.0543611 - ÚOCHB 2022 RIV US eng J - Journal Article
Pimková Polidarová, Markéta - Břehová, Petra - Kaiser, Martin Maxmilian - Smola, Miroslav - Dračínský, Martin - Smith, Joshua - Marek, Aleš - Dejmek, Milan - Šála, Michal - Gutten, Ondrej - Rulíšek, Lubomír - Novotná, Barbora - Brázdová, Andrea - Janeba, Zlatko - Nencka, Radim - Bouřa, Evžen - Páv, Ondřej - Birkuš, Gabriel
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP).
Journal of Medicinal Chemistry. Roč. 64, č. 11 (2021), s. 7596-7616. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
Institutional support: RVO:61388963
Keywords : DNA sensor * interferon genes * cyclic GMP-AMP
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c00301
Permanent Link: http://hdl.handle.net/11104/0320799 - 5.0541558 - ÚOCHB 2022 RIV DE eng J - Journal Article
Smola, Miroslav - Gutten, Ondrej - Dejmek, Milan - Kožíšek, Milan - Evangelidis, Thomas - Tehrani, Zahra Aliakbar - Novotná, Barbora - Nencka, Radim - Birkuš, Gabriel - Rulíšek, Lubomír - Bouřa, Evžen
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angewandte Chemie - International Edition. Roč. 60, č. 18 (2021), s. 10172-10178. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GA20-08772S; GA MŠMT(CZ) EF16_019/0000729
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963
Keywords : conformational analysis * cyclic dinucleotides * entropy * quantum chemistry * strain energy
OECD category: Physical chemistry
Impact factor: 16.823, year: 2021
Method of publishing: Open access
https://doi.org/10.1002/anie.202016805
Permanent Link: http://hdl.handle.net/11104/0319101 - 6.0519161 - ÚOCHB 2020 RIV US eng J - Journal Article
Novotná, Barbora - Vaneková, Lenka - Zavřel, Martin - Buděšínský, Miloš - Dejmek, Milan - Smola, Miroslav - Gutten, Ondrej - Tehrani, Zahra Aliakbar - Pimková Polidarová, Markéta - Brázdová, Andrea - Liboska, Radek - Štěpánek, Ivan - Vavřina, Zdeněk - Jandušík, Tomáš - Nencka, Radim - Rulíšek, Lubomír - Bouřa, Evžen - Brynda, Jiří - Páv, Ondřej - Birkuš, Gabriel
Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
Journal of Medicinal Chemistry. Roč. 62, č. 23 (2019), s. 10676-10690. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
Institutional support: RVO:61388963
Keywords : cyclic GMP-AMP * cytosolic DNA sensor * di-GMP
OECD category: Organic chemistry
Impact factor: 6.205, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.9b01062
Permanent Link: http://hdl.handle.net/11104/0304187