Search results
- 1.0547173 - ÚMCH 2022 RIV GB eng J - Journal Article
Šubr, Vladimír - Ormsby, Tereza - Šácha, Pavel - Konvalinka, Jan - Etrych, Tomáš - Kostka, Libor
The role of the biotin linker in polymer antibody mimetics, iBodies, in biochemical assays.
Polymer Chemistry. Roč. 12, č. 41 (2021), s. 6009-6021. ISSN 1759-9954. E-ISSN 1759-9962
R&D Projects: GA ČR(CZ) GA19-05649S; GA ČR(CZ) GA19-10280S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61389013 ; RVO:61388963
Keywords : HPMA * iBody * biotin
OECD category: Polymer science; Biochemical research methods (UOCHB-X)
Impact factor: 5.364, year: 2021
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2021/PY/D1PY00707F
Permanent Link: http://hdl.handle.net/11104/0324045 - 2.0544791 - ÚOCHB 2022 RIV FR eng J - Journal Article
Šimková, Adéla - Ormsby, Tereza - Sidej, Natan - Poštová Slavětínská, Lenka - Brynda, Jiří - Beranová, Jana - Šácha, Pavel - Majer, Pavel - Konvalinka, Jan
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
European Journal of Medicinal Chemistry. Roč. 224, Nov 15 (2021), č. článku 113717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : fibroblast activation protein * seprase * FAP inhibitor * serine protease inhibition * prolyl endopeptidase * α-Ketoamide inhibitor
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113717
Permanent Link: http://hdl.handle.net/11104/0321598 - 3.0525049 - ÚOCHB 2021 RIV US eng J - Journal Article
Tykvart, Jan - Navrátil, Václav - Kugler, Michael - Šácha, Pavel - Schimer, Jiří - Hlavačková, Anna - Tenora, Lukáš - Zemanová, Jitka - Dejmek, Milan - Král, V. - Potáček, M. - Majer, Pavel - Jahn, Ullrich - Brynda, Jiří - Řezáčová, Pavlína - Konvalinka, Jan
Identification of Novel Carbonic Anhydrase IX Inhibitors Using High-Throughput Screening of Pooled Compound Libraries by DNA-Linked Inhibitor Antibody Assay (DIANA).
SLAS Discovery. Roč. 25, č. 9 (2020), s. 1026-1037. ISSN 2472-5552. E-ISSN 2472-5560
R&D Projects: GA ČR(CZ) GA19-10280S; GA ČR(CZ) GA17-14510S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : high-throughput screening * carbonic anhydrase IX * drug discovery * DNA-linked inhibitor antibody assay
OECD category: Biochemistry and molecular biology
Impact factor: 2.918, year: 2020
Method of publishing: Limited access
https://journals.sagepub.com/doi/10.1177/2472555220918836
Permanent Link: http://hdl.handle.net/11104/0309265 - 4.0519252 - ÚOCHB 2020 RIV CH eng J - Journal Article
Beranová, Jana - Knedlík, Tomáš - Šimková, Adéla - Šubr, Vladimír - Kostka, Libor - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
Tris-(Nitrilotriacetic Acid)-Decorated Polymer Conjugates as Tools for Immobilization and Visualization of His-Tagged Proteins.
Catalysts. Roč. 9, č. 12 (2019), č. článku 1011. E-ISSN 2073-4344
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MPO(CZ) FV10490; GA MPO(CZ) FV10370; GA ČR(CZ) GA19-10280S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetics * protein immobilization * His-tag * tris-nitrilotriacetic acid (tris-NTA) * iBodies * biocompatible polymers * N-(2-hydroxypropyl) methacrylamide (HPMA)
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 3.520, year: 2019
Method of publishing: Open access
https://www.mdpi.com/2073-4344/9/12/1011
Permanent Link: http://hdl.handle.net/11104/0304263File Download Size Commentary Version Access 0519252.pdf 10 1.6 MB Publisher’s postprint open-access - 5.0509613 - ÚOCHB 2020 RIV NL eng J - Journal Article
Kryštůfek, Robin - Šácha, Pavel
Increasing the throughput of crystallization condition screens: Challenges and pitfalls of acoustic dispensing systems.
MethodsX. Roč. 6, Sep 25 (2019), s. 2230-2236. E-ISSN 2215-0161
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MPO(CZ) FV10490; GA ČR(CZ) GA19-10280S
Institutional support: RVO:61388963
Keywords : acoustic liquid transfer * protein crystallography * crystallization screening * laboratory automation
OECD category: Biochemical research methods
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2215016119302547?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0300302 - 6.0509610 - ÚOCHB 2020 RIV NL eng J - Journal Article
Kryštůfek, Robin - Šácha, Pavel
An iBody-based lateral flow assay for semi-quantitative determination of His-tagged protein concentration.
Journal of Immunological Methods. Roč. 473, Oct (2019), č. článku 112640. ISSN 0022-1759. E-ISSN 1872-7905
R&D Projects: GA ČR(CZ) GA19-10280S; GA MPO(CZ) FV10490; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : lateral flow assay * His-tag * antibody mimetics * protein quantitation
OECD category: Biochemical research methods
Impact factor: 1.901, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0022175919302091?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0300300