Search results
- 1.0541879 - ÚOCHB 2022 RIV US eng J - Journal Article
Perlíková, Pavla - Krajczyk, Anna - Doleželová, Eva - Slapničková, Martina - Milisavljevič, Nemanja - Poštová Slavětínská, Lenka - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Zíková, Alena - Hocek, Michal
Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides.
ACS Infectious Diseases. Roč. 7, č. 4 (2021), s. 917-926. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleosides * antiparasitic activity * antitrypanosomal * cytotoxicity
OECD category: Organic chemistry; Organic chemistry (BC-A)
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.1c00062
Permanent Link: http://hdl.handle.net/11104/0319376 - 2.0541603 - ÚOCHB 2022 RIV GB eng J - Journal Article
Nguyen, Van Hai - Tichý, Michal - Rožánková, Samanta - Pohl, Radek - Downey, Alan Michael - Doleželová, Eva - Tloušťová, Eva - Slapničková, Martina - Zíková, Alena - Hocek, Michal
Synthesis and anti-trypanosomal activity of 3′-fluororibonucleosides derived from 7-deazapurine nucleosides.
Bioorganic and Medicinal Chemistry Letters. Roč. 40, May 15 (2021), č. článku 127957. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleosides * deazapurines * fluorinated compounds * antiparasitic * anti-trypanosomal agents
OECD category: Organic chemistry; Organic chemistry (BC-A)
Impact factor: 2.940, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.bmcl.2021.127957
Permanent Link: http://hdl.handle.net/11104/0319136 - 3.0541460 - ÚOCHB 2022 RIV US eng J - Journal Article
Milisavljevič, Nemanja - Konkoľová, Eva - Kozák, Jaroslav - Hodek, Jan - Veselovská, Lucia - Sýkorová, Veronika - Čížek, Karel - Pohl, Radek - Eyer, Luděk - Svoboda, P. - Růžek, Daniel - Weber, Jan - Nencka, Radim - Bouřa, Evžen - Hocek, Michal
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses.
ACS Infectious Diseases. Roč. 7, č. 2 (2021), s. 471-478. ISSN 2373-8227
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LTAUSA18016; GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : 7-deazapurine ribonucleosides * monophosphate prodrugs * triphoshates * RNA viruses * 7-deazapurine ribonucleosides monophosphate prodrugs triphoshates RNA viruses antiviral activity
OECD category: Organic chemistry; Biochemistry and molecular biology (BC-A)
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.0c00829
Permanent Link: http://hdl.handle.net/11104/0319010 - 4.0534197 - ÚOCHB 2021 RIV US eng J - Journal Article
Veselovská, Lucia - Pohl, Radek - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines.
ACS Omega. Roč. 5, č. 40 (2020), s. 26278-26286. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA ČR(CZ) GA19-08124S; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : Thymidylate synthase inhibitors * receptor tyrosine kinase * biological activity
OECD category: Organic chemistry
Impact factor: 3.512, year: 2020
Method of publishing: Open access
https://doi.org/10.1021/acsomega.0c04302
Permanent Link: http://hdl.handle.net/11104/0312441 - 5.0532766 - ÚOCHB 2021 RIV DE eng J - Journal Article
Veselovská, Lucia - Kudlová, N. - Gurská, S. - Lišková, B. - Medvedíková, M. - Hodek, Ondřej - Tloušťová, Eva - Milisavljevič, Nemanja - Tichý, Michal - Perlíková, Pavla - Mertlíková-Kaiserová, Helena - Trylčová, Jana - Pohl, Radek - Klepetářová, Blanka - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
Chemistry - A European Journal. Roč. 26, č. 57 (2020), s. 13002-13015. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : antitumor agents * antiviral agents * drug discovery * phosphorylation * ribonucleosides
OECD category: Organic chemistry
Impact factor: 5.236, year: 2020
Method of publishing: Limited access
https://doi.org/10.1002/chem.202001124
Permanent Link: http://hdl.handle.net/11104/0311179 - 6.0532387 - ÚOCHB 2021 RIV US eng J - Journal Article
Fleuti, Marianne - Bártová, Kateřina - Poštová Slavětínská, Lenka - Tloušťová, Eva - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides.
Journal of Organic Chemistry. Roč. 85, č. 16 (2020), s. 10539-10551. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : tyrosine kinase * inhibitors * adenosine
OECD category: Organic chemistry
Impact factor: 4.354, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.joc.0c00928
Permanent Link: http://hdl.handle.net/11104/0310889 - 7.0531532 - ÚOCHB 2021 RIV US eng J - Journal Article
Yang, Chao - Pohl, Radek - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides.
Journal of Organic Chemistry. Roč. 85, č. 12 (2020), s. 8085-8101. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : nucleoside * inhibitors * antitumor
OECD category: Organic chemistry
Impact factor: 4.354, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.joc.0c00927
Permanent Link: http://hdl.handle.net/11104/0310168 - 8.0509096 - ÚOCHB 2020 RIV DE eng J - Journal Article
Malnuit, Vincent - Smolen, Sabina - Tichý, Michal - Poštová Slavětínská, Lenka - Hocek, Michal
Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6‐(Thiophen‐2‐yl)‐7‐fluoro‐7‐deazapurine.
European Journal of Organic Chemistry. Roč. 2019, 31/32 (2019), s. 5409-5423. ISSN 1434-193X. E-ISSN 1099-0690
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : 7‐deazapurine * nucleoside phosphonates * structure‐activity relationships * synthetic methods * sulfonamides
OECD category: Organic chemistry
Impact factor: 2.889, year: 2019
Method of publishing: Limited access
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.201900509
Permanent Link: http://hdl.handle.net/11104/0299888