Search results
- 1.0582961 - BC 2024 RIV US eng J - Journal Article
Penjarla, S. - Reddy, P.Y. - Penta, S. - Sanghvi, Y.S. - Eyer, Luděk - Štefánik, M. - Krátká, Z. - Růžek, Daniel - Banerjee, S.
Synthesis and Antiviral Activity of 2′-Modified L-Nucleoside Analogues.
ChemistrySelect. Roč. 8, č. 48 (2023), č. článku e202303585. ISSN 2365-6549. E-ISSN 2365-6549
R&D Projects: GA MŠMT(CZ) LTAUSA18016
Institutional support: RVO:60077344
Keywords : scale synthesis * pyrimidine * uridine * Antiviral Agent * L-2, 2'-anhydrouridine * L-Arabinose * Cytotoxicity * L-Nucleoside
OECD category: Microbiology
Impact factor: 2.1, year: 2022
Method of publishing: Limited access
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202303585
Permanent Link: https://hdl.handle.net/11104/0351001 - 2.0574490 - BC 2024 RIV NL eng J - Journal Article
Penjarla, S. - Reddy, P.Y. - Penta, S. - Sanghvi, Y.S. - Eyer, Luděk - Štefánik, M. - Růžek, Daniel - Banerjee, S.
Efficient synthesis of novel 2-deoxy-C-nucleosides containing oxa and thiadiazole derivatives and their biological activity.
Journal of Molecular Structure. Roč. 1292, NOV (2023), č. článku 136099. ISSN 0022-2860. E-ISSN 1872-8014
R&D Projects: GA MŠMT(CZ) LTAUSA18016
Institutional support: RVO:60077344
Keywords : Cnucleoside * Oxadiazoles * Thiadiazoles * Antiviral * Antitumor * Heterocycles
OECD category: Microbiology
Impact factor: 3.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0022286023011924?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0345916 - 3.0556963 - ÚOCHB 2023 RIV CH eng J - Journal Article
Konkoľová, Eva - Krejčová, Kateřina - Eyer, L. - Hodek, Jan - Zgarbová, Michala - Fořtová, A. - Jirásek, Michael - Teplý, Filip - Reyes Gutierrez, Paul Eduardo - Růžek, Daniel - Weber, Jan - Bouřa, Evžen
A Helquat-like Compound as a Potent Inhibitor of Flaviviral and Coronaviral Polymerases.
Molecules. Roč. 27, č. 6 (2022), č. článku 1894. E-ISSN 1420-3049
R&D Projects: GA ČR(CZ) GA21-25280S; GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LTAUSA18016
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : helquat-like compound * RNA-dependent RNA-polymerase * SARS-CoV-2 * flaviruses * antiviral agents
OECD category: Biochemistry and molecular biology; Microbiology (BC-A)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/molecules27061894
Permanent Link: http://hdl.handle.net/11104/0331081 - 4.0555514 - BC 2023 RIV CH eng J - Journal Article
Štefánik, M. - Bhosale, D. - Haviernik, Jan - Straková, Petra - Fojtiková, M. - Dufková, L. - Huvarová, I. - Salát, J. - Bartáček, J. - Svoboda, J. - Sedlák, M. - Růžek, Daniel - Miller, A. - Eyer, Luděk
Diphyllin Shows a Broad-Spectrum Antiviral Activity against Multiple Medically Important Enveloped RNA and DNA Viruses.
Viruses. Roč. 14, č. 2 (2022), č. článku 354. E-ISSN 1999-4915
R&D Projects: GA MŠMT(CZ) LTAUSA18016
Institutional support: RVO:60077344
Keywords : v-atpase inhibitor * lignans * glycosides * cells * arylnaphthalene * enveloped virus * diphyllin * cleistanthin B * vacuolar ATPase inhibitor * antiviral activity * cytotoxicity
OECD category: Microbiology
Impact factor: 4.7, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1999-4915/14/2/354
Permanent Link: https://hdl.handle.net/11104/0340396 - 5.0545098 - ÚOCHB 2022 RIV CH eng J - Journal Article
Dejmek, Milan - Konkoľová, Eva - Eyer, Luděk - Straková, Petra - Svoboda, Pavel - Šála, Michal - Krejčová, Kateřina - Růžek, Daniel - Bouřa, Evžen - Nencka, Radim
Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication.
Viruses. Roč. 13, č. 8 (2021), č. článku 1585. E-ISSN 1999-4915
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LTAUSA18016
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : non-nucleotide inhibitor * RNA-dependent RNA polymerase * SAR-CoV-2 * COVID-19 * antiviral agents
OECD category: Microbiology; Microbiology (BC-A)
Impact factor: 5.818, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/v13081585
Permanent Link: http://hdl.handle.net/11104/0321862 - 6.0541460 - ÚOCHB 2022 RIV US eng J - Journal Article
Milisavljevič, Nemanja - Konkoľová, Eva - Kozák, Jaroslav - Hodek, Jan - Veselovská, Lucia - Sýkorová, Veronika - Čížek, Karel - Pohl, Radek - Eyer, Luděk - Svoboda, P. - Růžek, Daniel - Weber, Jan - Nencka, Radim - Bouřa, Evžen - Hocek, Michal
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses.
ACS Infectious Diseases. Roč. 7, č. 2 (2021), s. 471-478. ISSN 2373-8227
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LTAUSA18016; GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : 7-deazapurine ribonucleosides * monophosphate prodrugs * triphoshates * RNA viruses * 7-deazapurine ribonucleosides monophosphate prodrugs triphoshates RNA viruses antiviral activity
OECD category: Organic chemistry; Biochemistry and molecular biology (BC-A)
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.0c00829
Permanent Link: http://hdl.handle.net/11104/0319010 - 7.0541187 - BC 2022 RIV US eng J - Journal Article
Eyer, Luděk - Svoboda, P. - Balvan, J. - Vicar, T. - Raudenská, M. - Štefánik, M. - Haviernik, J. - Huvarová, I. - Straková, P. - Rudolf, Ivo - Hubálek, Zdeněk - Seley-Radtke, K. - De Clercq, E. - Růžek, Daniel
Broad-spectrum antiviral activity of 3′-deoxy-3′-fluoroadenosine against emerging flaviviruses.
Antimicrobial Agents and Chemotherapy. Roč. 65, č. 2 (2021), č. článku e01522-20. ISSN 0066-4804. E-ISSN 1098-6596
R&D Projects: GA MŠMT(CZ) LTAUSA18016
Institutional support: RVO:60077344 ; RVO:68081766
Keywords : west nile virus * selective-inhibition * error catastrophe * in-vitro * borne * sofosbuvir * analogs * targets * future * agents * nucleoside analogue * 3'-deoxy-3'-fluoroadenosine * flavivirus * tick-borne encephalitis virus * antiviral activity * cytotoxicity * mouse model
OECD category: Microbiology; Microbiology (UBO-W)
Impact factor: 5.938, year: 2021
Method of publishing: Open access
https://aac.asm.org/content/65/2/e01522-20
Permanent Link: http://hdl.handle.net/11104/0318790