Search results
- 1.0577921 - ÚOCHB 2024 RIV GB eng J - Journal Article
Kraina, Pavel - Česnek, Michal - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Fulton, C. J. - Davidson, E. K. - Smith, B. P. - Watts, V. J. - Janeba, Zlatko
Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir.
Bioorganic & Medicinal Chemistry. Roč. 95, November (2023), č. článku 117508. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adefovir * 7-deazapurine * prodrugs * adenylate cyclase
OECD category: Organic chemistry
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2023.117508
Permanent Link: https://hdl.handle.net/11104/0346999 - 2.0551643 - ÚOCHB 2023 RIV DE eng J - Journal Article
Česnek, Michal - Šafránek, Michal - Dračínský, Martin - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Hayes, M. P. - Watts, V. J. - Janeba, Zlatko
Halogen-Dance-Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2-Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases.
ChemMedChem. Roč. 17, č. 1 (2022), č. článku e202100568. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adenylate cyclase * Bordetella pertussis * inhibitors * prodrugs
OECD category: Organic chemistry
Impact factor: 3.4, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/cmdc.202100568
Permanent Link: http://hdl.handle.net/11104/0326883 - 3.0547506 - ÚOCHB 2022 RIV US eng J - Journal Article
Kalčic, Filip - Zgarbová, Michala - Hodek, Jan - Chalupský, Karel - Dračínský, Martin - Dvořáková, Alexandra - Strmeň, Timotej - Šebestík, Jaroslav - Baszczyňski, Ondřej - Weber, Jan - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties.
Journal of Medicinal Chemistry. Roč. 64, č. 22 (2021), s. 16425-16449. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : chemistry * drug development * drug effect
OECD category: Organic chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acs.jmedchem.1c01444
Permanent Link: http://hdl.handle.net/11104/0323727 - 4.0543267 - ÚOCHB 2022 RIV FR eng J - Journal Article
Břehová, Petra - Chaloupecká, Ema - Česnek, Michal - Skácel, Jan - Dračínský, Martin - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Soto-Velasquez, M. P. - Watts, V. J. - Janeba, Zlatko
Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases.
European Journal of Medicinal Chemistry. Roč. 222, Oct 15 (2021), č. článku 113581. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adefovir * adenylate cyclase * Bacillus anthracis * Bordetella pertussis * inhibitors * prodrugs
OECD category: Organic chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.ejmech.2021.113581
Permanent Link: http://hdl.handle.net/11104/0320504 - 5.0543050 - ÚOCHB 2022 RIV GB eng J - Journal Article
Kalčic, Filip - Dračínský, Martin - Janeba, Zlatko
Diverse synthetic approaches towards C1′-branched acyclic nucleoside phosphonates.
Organic & Biomolecular Chemistry. Roč. 19, č. 32 (2021), s. 6958-6963. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : tenofovir alafenamide * medicinal chemistry * nucleotide analogs
OECD category: Organic chemistry
Impact factor: 3.890, year: 2021
Method of publishing: Limited access
https://doi.org/10.1039/D1OB00751C
Permanent Link: http://hdl.handle.net/11104/0320358 - 6.0532889 - ÚOCHB 2021 RIV CH eng J - Journal Article
Frydrych, Jan - Poštová Slavětínská, Lenka - Dračínský, Martin - Janeba, Zlatko
Efficient synthesis of α-branched purine-based acyclic nucleosides: Scopes and limitations of the method.
Molecules. Roč. 25, č. 18 (2020), č. článku 4307. E-ISSN 1420-3049
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclonucleosides * hemiaminal ether * purine * multi-component reaction
OECD category: Organic chemistry
Impact factor: 4.412, year: 2020
Method of publishing: Open access
https://doi.org/10.3390/molecules25184307
Permanent Link: http://hdl.handle.net/11104/0311284